Objective: Exposure to environmental noise might exert negative effects on cardiovascular function. Aim of the study is to explore whether sleep loss associated with exposure to aircraft noise has a detrimental effect on vascular function. Design and method: 22 individuals, heavily exposed (E) to aircraft noise (>50 DbA) were recruited and matched with a group of non-exposed individuals (NE). Pulse wave velocity (PWV), central blood pressure (BP), augmented pressure (AP) and augmentation index (Aix) were performed. 7-day actigraphy was performed for the assessment of total sleep time (TST) and wake after sleep onset (WASO). Results: E showed similar TST (7.2 ± 1.8 vs 7.1 ± 1.3 h, p = 0.77) and WASO (50 ± 46 vs 47 ± 30 min, p = 0.49) compared to NE. E showed higher Aix (26 ± 12 vs 14 ± 16, p = 0.006) and AP (11 ± 7 vs 7 ± 8, p = 0.03) than NE, in the presence of similar PWV, mean BP and heart rate (HR). In E group, Aix was related with height (r = -0.56, p = 0,009), TST (r = -0.65, p = 0.002), while was not related with age, mean BP, PWV and HR. The association remained significant in a multiple regression model (beta = -2.92, p = 0.01), with TST accounting for 12.9% of Aix variance (r2 full model 0.84). In NE Aix was related with age (r = -0.82, p < 0.001), HR (r = 0.76, p < 0.001), TST (r = -0.49, p = 0.01), mean BP (r = 0.61, p = 0.01), PWV (r = 0.57, p = 0.004). The only independent determinants of Aix in NE were age (beta = 0.64, p = 0.02) and HR (beta = -0.37, p = 0.03). Conclusions: Central pressure augmentation is independently affected by sleep duration in individuals exposed to high levels of environmental aircraft noise.

INCREASED CENTRAL PRESSURE AUGMENTATION IS ASSOCIATED WITH REDUCED SLEEP DURATION IN INDIVIDUALS EXPOSED TO AIRCRAFT NOISE POLLUTION: THE SERA-CV STUDY

Bruno R;Faraguna U;Di Pilla M;Banfi T;Gemignani A;Fidecaro F;Licitra G;Bonanni E;Berrettini S;Taddei S;Ghiadoni L
2017-01-01

Abstract

Objective: Exposure to environmental noise might exert negative effects on cardiovascular function. Aim of the study is to explore whether sleep loss associated with exposure to aircraft noise has a detrimental effect on vascular function. Design and method: 22 individuals, heavily exposed (E) to aircraft noise (>50 DbA) were recruited and matched with a group of non-exposed individuals (NE). Pulse wave velocity (PWV), central blood pressure (BP), augmented pressure (AP) and augmentation index (Aix) were performed. 7-day actigraphy was performed for the assessment of total sleep time (TST) and wake after sleep onset (WASO). Results: E showed similar TST (7.2 ± 1.8 vs 7.1 ± 1.3 h, p = 0.77) and WASO (50 ± 46 vs 47 ± 30 min, p = 0.49) compared to NE. E showed higher Aix (26 ± 12 vs 14 ± 16, p = 0.006) and AP (11 ± 7 vs 7 ± 8, p = 0.03) than NE, in the presence of similar PWV, mean BP and heart rate (HR). In E group, Aix was related with height (r = -0.56, p = 0,009), TST (r = -0.65, p = 0.002), while was not related with age, mean BP, PWV and HR. The association remained significant in a multiple regression model (beta = -2.92, p = 0.01), with TST accounting for 12.9% of Aix variance (r2 full model 0.84). In NE Aix was related with age (r = -0.82, p < 0.001), HR (r = 0.76, p < 0.001), TST (r = -0.49, p = 0.01), mean BP (r = 0.61, p = 0.01), PWV (r = 0.57, p = 0.004). The only independent determinants of Aix in NE were age (beta = 0.64, p = 0.02) and HR (beta = -0.37, p = 0.03). Conclusions: Central pressure augmentation is independently affected by sleep duration in individuals exposed to high levels of environmental aircraft noise.
2017
https://journals.lww.com/jhypertension/Abstract/2017/09002/_PP_19_25__INCREASED_CENTRAL_PRESSURE_AUGMENTATION.732.aspx
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11568/905775
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