Much of the chronic care of patients with type 2 diabetes mellitus and hypertension involves the prevention of diabetic complications. Renin-angiotensin system inhibitors are recommended as first-line therapies because of their nephroprotective properties. Their combination with metabolically neutral diuretics is recommended to reduce blood pressure, morbidity and mortality. Our objective was to review the mechanisms by which the combination of the angiotensin-converting enzyme inhibitor, perindopril, and metabolically neutral thiazide-like diuretic, indapamide, targets the pathways involved in microvascular and macrovascular diabetic complications.
Vascular legacy beyond blood pressure control: benefits of perindopril/indapamide combination in hypertensive patients with diabetes / Lévy, Bernard I; Taddei, Stefano. - In: CURRENT MEDICAL RESEARCH AND OPINION. - ISSN 0300-7995. - (2018), pp. 1-14-14.
|Autori:||Lévy, Bernard I; Taddei, Stefano|
|Titolo:||Vascular legacy beyond blood pressure control: benefits of perindopril/indapamide combination in hypertensive patients with diabetes|
|Anno del prodotto:||2018|
|Digital Object Identifier (DOI):||10.1080/03007995.2018.1425674|
|Appare nelle tipologie:||1.1 Articolo in rivista|