The possible relation between ear lobe crease (ELC) and coronary artery disease (CAD) was described for the first time by Frank in 1973 in a letter to the editor of the New England Journal of Medicine [1]. The author observed that 19 out of 20 patients with ELC had 1 or more risk factors for CAD, and he suggested that the presumptive relation should have been tested.

Ear lobe crease as a marker of coronary artery disease: a meta-analysis.

gensini, gianfranco;LUCENTEFORTE, ERSILIA
2014-01-01

Abstract

The possible relation between ear lobe crease (ELC) and coronary artery disease (CAD) was described for the first time by Frank in 1973 in a letter to the editor of the New England Journal of Medicine [1]. The author observed that 19 out of 20 patients with ELC had 1 or more risk factors for CAD, and he suggested that the presumptive relation should have been tested.
2014
Gensini, Gianfranco; Lucenteforte, Ersilia
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11568/914148
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