Novel amphiphilic random copolymers carrying poly(oxyethylene) and poly(siloxane) pendant chains are synthesized by atom transfer radical polymerization starting from either a fluorescent, julolidine-based initiator, or a nonfluorescent initiator. For both copolymer systems, dynamic light scattering measurements carried out on aqueous solutions as a function of temperature reveal the occurrence of a sharp and fully reversible transition between two different self-associative states of individual, single-chain self-folded nanoassemblies, so-called unimer micelles, (Dh= 8–10 nm) and collapsed multichain aggregates (Dh= 700–1400 nm) at a critical temperature Tc. Covalently linked julolidine terminal and added ethidium bromide are separately used as fluorescent probes and both prove the temperature-dependence of the different self-association of the copolymers in water.
The Temperature-Responsive Nanoassemblies of Amphiphilic Random Copolymers Carrying Poly(siloxane) and Poly(oxyethylene) Pendant Chains
Martinelli, ElisaPrimo
;ANNUNZIATA, LUISA;Guazzelli, Elisa;Pucci, Andrea;Biver, Tarita;Galli, Giancarlo
Ultimo
2018-01-01
Abstract
Novel amphiphilic random copolymers carrying poly(oxyethylene) and poly(siloxane) pendant chains are synthesized by atom transfer radical polymerization starting from either a fluorescent, julolidine-based initiator, or a nonfluorescent initiator. For both copolymer systems, dynamic light scattering measurements carried out on aqueous solutions as a function of temperature reveal the occurrence of a sharp and fully reversible transition between two different self-associative states of individual, single-chain self-folded nanoassemblies, so-called unimer micelles, (Dh= 8–10 nm) and collapsed multichain aggregates (Dh= 700–1400 nm) at a critical temperature Tc. Covalently linked julolidine terminal and added ethidium bromide are separately used as fluorescent probes and both prove the temperature-dependence of the different self-association of the copolymers in water.File | Dimensione | Formato | |
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