We read with great interest the meta-analysis of Vardakas et al. [1] which evaluated the effectiveness and safety of perioperative prophylaxis with teicoplanin, compared with first- or second-generation cephalosporins, in patients undergoing orthopaedic and vascular surgery. The authors concluded that both regimens are equally effective in terms of the development of infections, adverse effects and ortality, but suggested that large-scale use of teicoplanin cannot be recommended because of the likely emergence of resistance.
Teicoplanin use and emergence of Staphylococcus haemolyticus: is there a link?
Falcone M;
2006-01-01
Abstract
We read with great interest the meta-analysis of Vardakas et al. [1] which evaluated the effectiveness and safety of perioperative prophylaxis with teicoplanin, compared with first- or second-generation cephalosporins, in patients undergoing orthopaedic and vascular surgery. The authors concluded that both regimens are equally effective in terms of the development of infections, adverse effects and ortality, but suggested that large-scale use of teicoplanin cannot be recommended because of the likely emergence of resistance.File in questo prodotto:
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