Reactivities of human sera against selected recombinant Mycobacterium tuberculosis antigens were assessed by enzyme-linked immunosorbent assay. The results obtained indicate that patients with tuberculosis (TB) do not develop a strong humoral response against PE_PGRS and PPE proteins or against the Ag85B and heparin-binding hemagglutinin (HBHA) recombinant antigens. Conversely, purified methylated HBHA was strongly recognized by sera obtained from TB patients compared to controls.
|Autori interni:||GARZELLI, CARLO|
|Autori:||ZANETTI; S.; A. BUA; G. DELOGU; C. PUSCEDDU; M. MURA; F. SABA; P. PIRINA; GARZELLI C; C. VERTUCCIO; L.A. SECHI; G. FADDA G.|
|Titolo:||Patients with Pulmonary Tuberculosis Develop a Strong Humoral Response against Methylated Heparin-Binding Hemagglutinin|
|Anno del prodotto:||2005|
|Digital Object Identifier (DOI):||10.1128/CDLI.12.9.1135-1138.2005|
|Appare nelle tipologie:||1.1 Articolo in rivista|