The process of ageing denotes a postmaturational deterioration of cells and organisms with the passage of time, an increased vulnerability to challenges and a decreased ability to survive. Causes may be found in oxidative damage and not completed cell maintenance, and both of these factors may be considered the primary targets of any antiageing therapy. Levels of lipophylic antioxidant defenses may be the limiting factor of longevity in ad libitum fed animals. An appropriate administration of lipophylic anti-oxidants (polyunsaturated fatty acids, Vitamin E etc) and the stimulation of cytomembranes and organelles renewal by calorie restriction and pharmacological intensification of autophagy are currently available interventions that may extend longevity and retard the onset and help treatment of most age-associated diseases.
|Autori interni:||GORI, ZINA|
|Autori:||GORI Z; CAVALLINI G; DONATI A; BERGAMINI E|
|Titolo:||Recenti progressi della terapia anti-invecchiamento|
|Anno del prodotto:||2005|
|Appare nelle tipologie:||1.1 Articolo in rivista|