Semi-interpenetrating hydrogel networks were prepared by radical polimerization of monomer HEMA, co-monomer EGDMA as cross-linking agent and in the presence of 1 wt % of poly(alkyl beta-malolactonate)s. Biological evaluation in terms of cell adhesion and proliferation of the prepared materials showed the ability of HEMA-based hydrogels to sustain a good cell adhesion and proliferation. Moreover, a method based on soft-lithography to obtained surface microstructured semi-interpenetrating hydrogel networks was developed, thus allowing for further investigation of the influence of surface topography on cell behavior.

Surface patterning and biological evaluation of semi-interpenetrated poly(HEMA)/poly(alkyl beta-malolactonate)s

Chiellini F;Bizzarri R;
2003-01-01

Abstract

Semi-interpenetrating hydrogel networks were prepared by radical polimerization of monomer HEMA, co-monomer EGDMA as cross-linking agent and in the presence of 1 wt % of poly(alkyl beta-malolactonate)s. Biological evaluation in terms of cell adhesion and proliferation of the prepared materials showed the ability of HEMA-based hydrogels to sustain a good cell adhesion and proliferation. Moreover, a method based on soft-lithography to obtained surface microstructured semi-interpenetrating hydrogel networks was developed, thus allowing for further investigation of the influence of surface topography on cell behavior.
2003
Chiellini, F; Bizzarri, R; Ober, Ck; Schmaljiohann, D; Yu, Ty; Saltzman, Wm; Solaro, R; Chiellini, E
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11568/991357
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