Sfoglia per Autore
Identification of new FYN kinase inhibitors using a FLAP-based approach
2013-01-01 Poli, Giulio; Tuccinardi, Tiziano; Rizzolio, Flavio; Caligiuri, Isabella; Botta, Lorenzo; Granchi, Carlotta; Ortore, GABRIELLA MARIA PIA; Minutolo, Filippo; Schenone, Silvia; Martinelli, Adriano
Assessing the differential action on cancer cells of LDH-A inhibitors based on the N-hydroxyindole-2-carboxylate (NHI) and malonic (Mal) scaffolds
2013-01-01 Granchi, Carlotta; Emilia C., Calvaresi; Tuccinardi, Tiziano; Paterni, Ilaria; Macchia, Marco; Martinelli, Adriano; Paul J., Hergenrother; Minutolo, Filippo
Salicylaldoxime derivatives as new leads for the development of carbonic anhydrase inhibitors
2013-01-01 Tuccinardi, Tiziano; Bertini, Simone; Granchi, Carlotta; Ortore, GABRIELLA MARIA PIA; Macchia, Marco; Minutolo, Filippo; Martinelli, Adriano; C. T., Supuran
Identification of LDH-A as a therapeutic target for cancer cell killing via (i) p53/NAD(H)-dependent and (ii) p53-independent pathways
2014-01-01 Simon, Allison; John, Knight; Granchi, Carlotta; Rani, Reshma; Minutolo, Filippo; Jo, Milner; Roger, Phillips
Synergistic interaction of novel lactate dehydrogenase inhibitors with gemcitabine against pancreatic cancer cells in hypoxia.
2014-01-01 Maftouh, M; Avan, A; Sciarrillo, R; Granchi, Carlotta; Leon, Lg; Rani, R; Funel, Niccola; Smid, K; Honeywell, R; Boggi, Ugo; Minutolo, F; Peters, Gj; Giovannetti, Elisa
An update on therapeutic opportunities offered by cancer glycolytic metabolism
2014-01-01 Granchi, Carlotta; Fancelli, D.; Minutolo, Filippo
Identification and characterization of a new reversible MAGL inhibitor
2014-01-01 Tuccinardi, Tiziano; Granchi, Carlotta; Rizzolio, F; Caligiuri, I; Battistello, V; Toffoli, G; Minutolo, Filippo; Macchia, Marco; Martinelli, Adriano
Synergistic interaction of novel lactate dehydrogenase inhibitors with gemcitabine against pancreatic cancer cells in hypoxia
2014-01-01 Mina, Maftouh; Amir, Avan; Rocco, Sciarrillo; Granchi, Carlotta; Leticia G., Leon; Rani, Reshma; Funel, Niccola; Kees, Smid; Richard, Honeywell; Boggi, Ugo; Minutolo, Filippo; Godefridus J., Peters; Elisa, Giovannetti
Estrogen Receptors Alpha (ERα) and Beta (ERβ): Subtype-Selective Ligands and Clinical Potential
2014-01-01 Paterni, Ilaria; Granchi, Carlotta; John A., Katzenellenbogen; Minutolo, Filippo
Receptor-based virtual screening evaluation for the identification of estrogen receptor β ligands
2015-01-01 Tuccinardi, Tiziano; Poli, Giulio; Dell’Agnello, M; Granchi, Carlotta; Minutolo, Filippo; Martinelli, Adriano
Development and validation of a docking-based virtual screening platform for the identification of new lactate dehydrogenase inhibitors
2015-01-01 Granchi, Carlotta; Capecchi, Alice; Del Frate, Gianluca; Martinelli, Adriano; Macchia, Marco; Minutolo, Filippo; Tuccinardi, Tiziano
Phenylpropanoids and flavonoids from Phlomis kurdica as inhibitors of human lactate dehydrogenase.
2015-01-01 Bader, A; Tuccinardi, Tiziano; Granchi, Carlotta; Martinelli, Adriano; Macchia, Marco; Minutolo, Filippo; De Tommasi, N; Braca, Alessandra
Highly Selective Salicylketoxime-Based Estrogen Receptor β Agonists Display Antiproliferative Activities in a Glioma Model
2015-01-01 Paterni, Ilaria; Bertini, Simone; Granchi, Carlotta; Tuccinardi, Tiziano; Macchia, Marco; Martinelli, Adriano; Isabella, Caligiuri; Giuseppe, Toffoli; Flavio, Rizzolio; Kathryn E., Carlson; Benita S., Katzenellenbogen; John A., Katzenellenbogen; Minutolo, Filippo
Lactate dehydrogenase-A inhibition induces human glioblastoma multiforme stem cell differentiation and death
2015-01-01 Daniele, Simona; Giacomelli, Chiara; Zappelli, Elisa; Granchi, Carlotta; Trincavelli, MARIA LETIZIA; Minutolo, Filippo; Martini, Claudia
Salicylketoximes that target glucose transporter 1 restrict energy supply to lung cancer cells
2015-01-01 Granchi, Carlotta; Qian, Yanrong; Lee, Hyang Yeon; Paterni, Ilaria; Pasero, Carolina; Iegre, Jessica; Carlson, Kathryn E; Tuccinardi, Tiziano; Chen, Xiaozhuo; Katzenellenbogen, John A; Hergenrother, Paul J; Minutolo, Filippo
Synthesis and biological evaluation of non-glucose glycoconjugated N-hydroyxindole class LDH inhibitors as anticancer agents
2015-01-01 DI BUSSOLO, Valeria; Emilia, Calvaresi; Granchi, Carlotta; Linda Del, Bino; Ileana, Frau; Maria Chiara Dasso, Lang; Tuccinardi, Tiziano; Macchia, Marco; Martinelli, Adriano; Paul J., Hergenrother; Minutolo, Filippo
Bioactive heterocycles containing endocyclic N-hydroxy groups
2015-01-01 Rani, Reshma; Granchi, Carlotta
Structural optimization of 4-chlorobenzoylpiperidine derivatives for the development of potent, reversible and selective monoacylglycerol lipase (MAGL) inhibitors
2016-01-01 Granchi, Carlotta; Rizzolio, Flavio; Palazzolo, Stefano; Carmignani, Sara; Macchia, Marco; Saccomanni, Giuseppe; Manera, Clementina; Martinelli, Adriano; Minutolo, Filippo; Tuccinardi, Tiziano
Synthesis and biological evalutation of new glycoconjugated LDH inhibitors as anticancer agents
2016-01-01 D'Andrea, Felicia; DI BUSSOLO, Valeria; Granchi, Carlotta; Lee, Hyang Yeon; Hergenrother, Paul J.; Minutolo, Filippo; Vagelli, Giulia
Anticancer agents interacting with membrane glucose transporters
2016-01-01 Granchi, Carlotta; Fortunato, Serena; Minutolo, Filippo
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Identification of new FYN kinase inhibitors using a FLAP-based approach | 1-gen-2013 | Poli, Giulio; Tuccinardi, Tiziano; Rizzolio, Flavio; Caligiuri, Isabella; Botta, Lorenzo; Granchi, Carlotta; Ortore, GABRIELLA MARIA PIA; Minutolo, Filippo; Schenone, Silvia; Martinelli, Adriano | |
| Assessing the differential action on cancer cells of LDH-A inhibitors based on the N-hydroxyindole-2-carboxylate (NHI) and malonic (Mal) scaffolds | 1-gen-2013 | Granchi, Carlotta; Emilia C., Calvaresi; Tuccinardi, Tiziano; Paterni, Ilaria; Macchia, Marco; Martinelli, Adriano; Paul J., Hergenrother; Minutolo, Filippo | |
| Salicylaldoxime derivatives as new leads for the development of carbonic anhydrase inhibitors | 1-gen-2013 | Tuccinardi, Tiziano; Bertini, Simone; Granchi, Carlotta; Ortore, GABRIELLA MARIA PIA; Macchia, Marco; Minutolo, Filippo; Martinelli, Adriano; C. T., Supuran | |
| Identification of LDH-A as a therapeutic target for cancer cell killing via (i) p53/NAD(H)-dependent and (ii) p53-independent pathways | 1-gen-2014 | Simon, Allison; John, Knight; Granchi, Carlotta; Rani, Reshma; Minutolo, Filippo; Jo, Milner; Roger, Phillips | |
| Synergistic interaction of novel lactate dehydrogenase inhibitors with gemcitabine against pancreatic cancer cells in hypoxia. | 1-gen-2014 | Maftouh, M; Avan, A; Sciarrillo, R; Granchi, Carlotta; Leon, Lg; Rani, R; Funel, Niccola; Smid, K; Honeywell, R; Boggi, Ugo; Minutolo, F; Peters, Gj; Giovannetti, Elisa | |
| An update on therapeutic opportunities offered by cancer glycolytic metabolism | 1-gen-2014 | Granchi, Carlotta; Fancelli, D.; Minutolo, Filippo | |
| Identification and characterization of a new reversible MAGL inhibitor | 1-gen-2014 | Tuccinardi, Tiziano; Granchi, Carlotta; Rizzolio, F; Caligiuri, I; Battistello, V; Toffoli, G; Minutolo, Filippo; Macchia, Marco; Martinelli, Adriano | |
| Synergistic interaction of novel lactate dehydrogenase inhibitors with gemcitabine against pancreatic cancer cells in hypoxia | 1-gen-2014 | Mina, Maftouh; Amir, Avan; Rocco, Sciarrillo; Granchi, Carlotta; Leticia G., Leon; Rani, Reshma; Funel, Niccola; Kees, Smid; Richard, Honeywell; Boggi, Ugo; Minutolo, Filippo; Godefridus J., Peters; Elisa, Giovannetti | |
| Estrogen Receptors Alpha (ERα) and Beta (ERβ): Subtype-Selective Ligands and Clinical Potential | 1-gen-2014 | Paterni, Ilaria; Granchi, Carlotta; John A., Katzenellenbogen; Minutolo, Filippo | |
| Receptor-based virtual screening evaluation for the identification of estrogen receptor β ligands | 1-gen-2015 | Tuccinardi, Tiziano; Poli, Giulio; Dell’Agnello, M; Granchi, Carlotta; Minutolo, Filippo; Martinelli, Adriano | |
| Development and validation of a docking-based virtual screening platform for the identification of new lactate dehydrogenase inhibitors | 1-gen-2015 | Granchi, Carlotta; Capecchi, Alice; Del Frate, Gianluca; Martinelli, Adriano; Macchia, Marco; Minutolo, Filippo; Tuccinardi, Tiziano | |
| Phenylpropanoids and flavonoids from Phlomis kurdica as inhibitors of human lactate dehydrogenase. | 1-gen-2015 | Bader, A; Tuccinardi, Tiziano; Granchi, Carlotta; Martinelli, Adriano; Macchia, Marco; Minutolo, Filippo; De Tommasi, N; Braca, Alessandra | |
| Highly Selective Salicylketoxime-Based Estrogen Receptor β Agonists Display Antiproliferative Activities in a Glioma Model | 1-gen-2015 | Paterni, Ilaria; Bertini, Simone; Granchi, Carlotta; Tuccinardi, Tiziano; Macchia, Marco; Martinelli, Adriano; Isabella, Caligiuri; Giuseppe, Toffoli; Flavio, Rizzolio; Kathryn E., Carlson; Benita S., Katzenellenbogen; John A., Katzenellenbogen; Minutolo, Filippo | |
| Lactate dehydrogenase-A inhibition induces human glioblastoma multiforme stem cell differentiation and death | 1-gen-2015 | Daniele, Simona; Giacomelli, Chiara; Zappelli, Elisa; Granchi, Carlotta; Trincavelli, MARIA LETIZIA; Minutolo, Filippo; Martini, Claudia | |
| Salicylketoximes that target glucose transporter 1 restrict energy supply to lung cancer cells | 1-gen-2015 | Granchi, Carlotta; Qian, Yanrong; Lee, Hyang Yeon; Paterni, Ilaria; Pasero, Carolina; Iegre, Jessica; Carlson, Kathryn E; Tuccinardi, Tiziano; Chen, Xiaozhuo; Katzenellenbogen, John A; Hergenrother, Paul J; Minutolo, Filippo | |
| Synthesis and biological evaluation of non-glucose glycoconjugated N-hydroyxindole class LDH inhibitors as anticancer agents | 1-gen-2015 | DI BUSSOLO, Valeria; Emilia, Calvaresi; Granchi, Carlotta; Linda Del, Bino; Ileana, Frau; Maria Chiara Dasso, Lang; Tuccinardi, Tiziano; Macchia, Marco; Martinelli, Adriano; Paul J., Hergenrother; Minutolo, Filippo | |
| Bioactive heterocycles containing endocyclic N-hydroxy groups | 1-gen-2015 | Rani, Reshma; Granchi, Carlotta | |
| Structural optimization of 4-chlorobenzoylpiperidine derivatives for the development of potent, reversible and selective monoacylglycerol lipase (MAGL) inhibitors | 1-gen-2016 | Granchi, Carlotta; Rizzolio, Flavio; Palazzolo, Stefano; Carmignani, Sara; Macchia, Marco; Saccomanni, Giuseppe; Manera, Clementina; Martinelli, Adriano; Minutolo, Filippo; Tuccinardi, Tiziano | |
| Synthesis and biological evalutation of new glycoconjugated LDH inhibitors as anticancer agents | 1-gen-2016 | D'Andrea, Felicia; DI BUSSOLO, Valeria; Granchi, Carlotta; Lee, Hyang Yeon; Hergenrother, Paul J.; Minutolo, Filippo; Vagelli, Giulia | |
| Anticancer agents interacting with membrane glucose transporters | 1-gen-2016 | Granchi, Carlotta; Fortunato, Serena; Minutolo, Filippo |
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