Sfoglia per Autore
Proposal of an unified model for the interpretation of the activity of different classes of beta-adrenergic agents
1975-01-01 Ammon, H. L.; Balsamo, Aldo; Macchia, B; Macchia, F; HOWE DONNA, B; Keefe, W. E.
Studies of the relations between molecular conformation and pharmacological activity by x-ray diffraction, part II. The crystal structures of dichloroisoproterenol, propranolol and propranolol hydrochloride
1977-01-01 AMMON HERMAN, L; HOWE DONNA, B; ERHARDT W., David; Balsamo, Aldo; Macchia, Bruno; Macchia, Franco; KEEFE WILLIAM, E.
Crystal and molecular structure of 4-acetyl-3-methyl-7beta-phenoxyacetamido-delta3-cephem
1978-01-01 Domiano, Paolo; Nardelli, Mario; Balsamo, Aldo; Macchia, Bruno; Macchia, Franco; Meinardi, Giuseppe
Crystal and molecular structure of p-methoxybenzyl 2alpha-methyl-2beta-[(R)-acetoxy(methoxy)methyl]-6beta -phenoxyacetamidopenam-3alpha-carboxylate
1979-01-01 Domiano, Paolo; Nardelli, Mario; Balsamo, Aldo; Macchia, Bruno; Macchia, Franco
Synthesis, molecular properties and pharmacological activity of some p-substituted (E)- and (Z)-alpha,beta-dimethylcinnamic acids
1980-01-01 Balsamo, Aldo; Crotti, Paolo; Macchia, Bruno; Macchia, Franco; Martinelli, Adriano; Santini, Sergio; Sorriso, Salvatore
Synthesis, molecular properties and pharmacological activity of some p-substituted (E)- and (Z)-alpha,beta-dimethylcinnamic acids
1980-01-01 Balsamo, Aldo; Crotti, Paolo; Macchia, Bruno; Macchia, Franco; Martinelli, Adriano; Santini, Sergio; Sorriso, Salvatore
Synthesis, molecular properties and pharmacological activity of some p-substituted (E)- and (Z)-alpha,beta-dimethylcinnamic acids
1980-01-01 Balsamo, Aldo; Crotti, Paolo; Macchia, Bruno; Macchia, Franco; Martinelli, Adriano; Santini, Sergio; Sorriso, Salvatore
Importance of the substituent on C(2) in the interconversion of the thiazine and thiazolidine system of β -lactam antibiotics
1980-01-01 Balsamo, Aldo; Giorgi, Irene; Macchia, Bruno; Macchia, Franco; Rosai, Antonio; Domiano, Paolo; Nannini, Giuliano
Is the conformation of the thiazolidine ring of penicillins of any importance for their antibacterial activity?
1980-01-01 Balsamo, Aldo; Domiano, Paolo; Macchia, Bruno; Macchia, Franco; Nardelli, Mario
Importance of the C(3) substituent of the penam derivative in interconversion reactions of penam and cepham systems
1984-01-01 Balsamo, Aldo; BENEDINI PAOLA, Maria; Macchia, Bruno; Macchia, Franco; Rossello, Armando
3-(4-iodomethyl-2-oxo-1-azetidinyl)propynoic acid t-butyl ester: A new ß-lactam derivative. Synthesis of an ynamide by reaction of 4-iodomethylazetidin-2-one with the t-butyl ester of propiolic acid in the presence of copper (I)
1985-01-01 Balsamo, Aldo; Macchia, Bruno; F. MACCHIA E. P., Domiano; Rossello, Armando
Crystal and molecular structure of (3R)-3-(3-methyl-7-phenoxyacetamido-3-cephem-4-yl)-3-hydroxybutanoic acid
1987-01-01 Domiano, Paolo; Balsamo, Aldo; Macchia, Bruno; Macchia, Franco
SYNTHESIS AND EVALUATION OF THE PHARMACOLOGICAL ACTIVITY OF RIGID ANALOGUES OF SYMPATHOMIMETIC DERIVED FROM BICYCLO[2.2.1]HEPTANE
1989-01-01 Balsamo, Aldo; Breschi, MARIA CRISTINA; Lapucci, Annalina; Macchia, B; Macchia, Franco; Martinotti, Enrica; Nencetti, Susanna; Nieri, Paola; Orlandini, Elisabetta
SYNTHESIS AND EVALUATION OF THE PHARMACOLOGICAL ACTIVITY OF RIGID ANALOGS OF SYMPATHOMIMETIC CATECHOLAMINES DERIVED FROM BICYCLO[2.2.1]HEPTANE
1989-01-01 Balsamo, Aldo; Breschi, MARIA CRISTINA; Lapucci, Annalina; Macchia, Bruno; Macchia, F; Martinotti, E; Nencetti, Susanna; Nieri, Paola; Orlandini, Elisabetta
Conformational effects on the activity of drugs. 13. A revision of previously proposed models for the activation of alfa- and beta-adrenergic receptors
1992-01-01 Macchia, B; Balsamo, Aldo; Breschi, M. C.; Lapucci, A; Lucacchini, Antonio; Macchia, F; Manera, Clementina; Martinelli, A; Martinotti, E; Nencetti, S.
The [(Methyloxy)imino]methyl Moiety as a Bioisoster of Aryl. A Novel Class of Completely Aliphatic Beta-Adrenergic Receptor Antagonists
1994-01-01 Macchia, Bruno; Balsamo, Aldo; Breschi, MARIA CRISTINA; Chiellini, Grazia; Macchia, Marco; Martinelli, Adriano; Martini, Claudia; Nardini, C; Nencetti, Susanna; Rossello, Armando; Scatizzi, R.
Conformationally restrained β -blocking oxime ethers. 4. Chiral 2-(3'-(5'-p-chlorophenyl)isoxazolidinyl)ethanolamines as conformationally restrained analogs of methyloxyiminomethyl (MOIM) β -adrenergic antagonists: synthesis, configuration and β -adrenergic properties
1996-01-01 Balsamo, Aldo; Breschi, M. C.; Chiellini, G; Cozzini, P; Domiano, P; Macchia, Marco; Manera, Clementina; Martinelli, A; Nencetti, S.
Synthesis and alfa2-adrenergic activity of 2-(methyleneamino)oxy-N-(guanidino)ethaneimines. A bioisosteric replacementof the aryl of guanabenz-type benzylideneaminoguanidinic alfa2-agnists with the (methyleneamino)oxymethyl moiety
1996-01-01 Balsamo, Aldo; Gentili, D.; Macchia, Marco; Martinotti, E.; Rossello, Armando; Scatizzi, R.
Preparation and antiproliferative activity of phosphorus- and sulfur-containing geranylgeranyl derivatives
1997-01-01 Balsamo, Aldo; Macchia, Bruno; Macchia, Marco; Baldacci, Massimo; Danesi, Romano; DEL TACCA, Mario
process for the preparation of ceramide analogs and their use as antitumor agents
2001-01-01 Macchia, Bruno; Balsamo, Aldo; Macchia, Marco; DEL TACCA, Mario; Danesi, Romano
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