Sfoglia per Autore
Pharmacophore modeling for qualitative prediction of antiestrogenic activity
2009-01-01 Brogi, S.; Kladi, M.; Vagias, C.; Papazafiri, P.; Roussis, V.; Tafi, A.
Pharmacophore modeling: A continuously evolving tool for computational drug design
2009-01-01 Tafi, Andrea; Bellucci, Luca; Brogi, Simone; Caporuscio, Fabiana; Olla, Stefania
Tetrahydrofuran acetogenins from Laurencia glandulifera
2009-01-01 Kladi, M.; Vagias, C.; Papazafiri, P.; Brogi, S.; Tafi, A.; Roussis, V.
Three-dimensional quantitative structure-selectivity relationships analysis guided rational design of a highly selective ligand for the cannabinoid receptor 2
2011-01-01 Brogi, S.; Corelli, F.; Di Marzo, V.; Ligresti, A.; Mugnaini, C.; Pasquini, S.; Tafi, A.
Synthesis and antiplasmodial activity of bicyclic dioxanes as simplified dihydroplakortin analogues
2011-01-01 Gemma, S.; Kunjir, S.; Sanna Coccone, S.; Brindisi, M.; Moretti, V.; Brogi, S.; Novellino, E.; Basilico, N.; Parapini, S.; Taramelli, D.; Campiani, G.; Butini, S.
PROKINETICIN 1 RECEPTOR AGONISTS AND THEIR USES
2012-01-01 Desaubry, Laurent; Desaubry, Gunsel Canan; Boulberdaa, Mounia; Kindo, Michel; Tafi, Andrea; Brogi, Simone; Urayama, Kyoji; Ribeiro, Nigel
Optimization of 4-aminoquinoline/clotrimazole-based hybrid antimalarials: Further structure-activity relationships, in vivo studies, and preliminary toxicity profiling
2012-01-01 Gemma, S.; Camodeca, C.; Sanna Coccone, S.; Joshi, B. P.; Bernetti, M.; Moretti, V.; Brogi, S.; De Marcos, M. C. B.; Savini, L.; Taramelli, D.; Basilico, N.; Parapini, S.; Rottmann, M.; Brun, R.; Lamponi, S.; Caccia, S.; Guiso, G.; Summers, R. L.; Martin, R. E.; Saponara, S.; Gorelli, B.; Novellino, E.; Campiani, G.; Butini, S.
Characterization of COR627 and COR628, two novel positive allosteric modulators of the GABA B receptor
2012-01-01 Castelli, M. P.; Casu, A.; Casti, P.; Lobina, C.; Carai, M. A. M.; Colombo, G.; Solinas, M.; Giunta, D.; Mugnaini, C.; Pasquini, S.; Tafi, A.; Brogi, S.; Gessa, G. L.; Corelli, F.
Quinolylhydrazones as novel inhibitors of Plasmodium falciparum serine protease PfSUB1
2012-01-01 Gemma, S.; Giovani, S.; Brindisi, M.; Tripaldi, P.; Brogi, S.; Savini, L.; Fiorini, I.; Novellino, E.; Butini, S.; Campiani, G.; Penzo, M.; Blackman, M. J.
Design, synthesis, and pharmacological characterization of indol-3-ylacetamides, indol-3-yloxoacetamides, and indol-3-ylcarboxamides: Potent and selective CB2 cannabinoid receptor inverse agonists
2012-01-01 Pasquini, S.; Mugnaini, C.; Ligresti, A.; Tafi, A.; Brogi, S.; Falciani, C.; Pedani, V.; Pesco, N.; Guida, F.; Luongo, L.; Varani, K.; Borea, P. A.; Maione, S.; Di Marzo, V.; Corelli, F.
Mimicking the intramolecular hydrogen bond: Synthesis, biological evaluation, andmolecular modeling of benzoxazines and quinazolines as potential antimalarial agents
2012-01-01 Gemma, S.; Camodeca, C.; Brindisi, M.; Brogi, S.; Kukreja, G.; Kunjir, S.; Gabellieri, E.; Lucantoni, L.; Habluetzel, A.; Taramelli, D.; Basilico, N.; Gualdani, R.; Tadini-Buoninsegni, F.; Bartolommei, G.; Moncelli, M. R.; Martin, R. E.; Summers, R. L.; Lamponi, S.; Savini, L.; Fiorini, I.; Valoti, M.; Novellino, E.; Campiani, G.; Butini, S.
Synthesis and structure-activity relationship studies in serotonin 5-HT1A receptor agonists based on fused pyrrolidone scaffolds
2013-01-01 Cappelli, A.; Manini, M.; Valenti, S.; Castriconi, F.; Giuliani, G.; Anzini, M.; Brogi, S.; Butini, S.; Gemma, S.; Campiani, G.; Giorgi, G.; Mennuni, L.; Lanza, M.; Giordani, A.; Caselli, G.; Letari, O.; Makovec, F.
Multifunctional cholinesterase and amyloid beta fibrillization modulators. Synthesis and biological investigation
2013-01-01 Butini, S.; Brindisi, M.; Brogi, S.; Maramai, S.; Guarino, E.; Panico, A.; Saxena, A.; Chauhan, V.; Colombo, R.; Verga, L.; De Lorenzi, E.; Bartolini, M.; Andrisano, V.; Novellino, E.; Campiani, G.; Gemma, S.
The structural evolution of β-secretase inhibitors: A focus on the development of small-molecule inhibitors
2013-01-01 Butini, S.; Brogi, S.; Novellino, E.; Campiani, G.; Ghosh, A. K.; Brindisi, M.; Gemma, S.
A stereoselective approach to peptidomimetic BACE1 inhibitors
2013-01-01 Butini, S.; Gabellieri, E.; Brindisi, M.; Giovani, S.; Maramai, S.; Kshirsagar, G.; Guarino, E.; Brogi, S.; La Pietra, V.; Giustiniano, M.; Marinelli, L.; Novellino, E.; Campiani, G.; Cappelli, A.; Gemma, S.
NOVEL ANALGESIC/ANTI-INFLAMMATORY AGENTS: 1,5-DIARYLPYRROLE NITROOXYALKYL ETHERS AND RELATED COMPOUNDS AS CYCLOOXYGENASE-2 INHIBITING NITRIC OXIDE DONORS
2013-01-01 M., Anzini; A., DI CAPUA; S., Valenti; Brogi, Simone; M., Rovini; G., Giuliani; A., Cappelli; S., Vomero; L., Chiasserini; A., Sega; G., Poce; G., Giorgi; Calderone, Vincenzo; Martelli, Alma; Testai, Lara; L., Sautebin; A., Rossi; S., Pace; C., Ghelardini; L., DI CESARE MANNELLI; V., Benetti; A., Giordani; P., Anzellotti; M., Dovizio; P., Patrignani; M., Biava
3D-QSAR using pharmacophore-based alignment and virtual screening for discovery of novel MCF-7 cell line inhibitors
2013-01-01 Brogi, S.; Papazafiri, P.; Roussis, V.; Tafi, A.
0365: Non-peptidic prokineticin receptor 1 agonist as a novel cardioprotective therapeutic
2014-01-01 Gasser, Adeline; Nishi, Toshihide; Nguyen, Thu Lan; Urayama, Kyoji; Kurose, Hitoshi; Charavin, Marine; Brogi, Simone; Tafi, Andrea; Desaubry, Laurent; Nebigil, Canan
Discovery of GPCR ligands for probing signal transduction pathways
2014-01-01 Brogi, S.; Tafi, A.; Desaubry, L.; Nebigil, C. G.
Disease-modifying anti-Alzheimer's drugs: Inhibitors of human cholinesterases interfering with β-amyloid aggregation
2014-01-01 Brogi, S.; Butini, S.; Maramai, S.; Colombo, R.; Verga, L.; Lanni, C.; De Lorenzi, E.; Lamponi, S.; Andreassi, M.; Bartolini, M.; Andrisano, V.; Novellino, E.; Campiani, G.; Brindisi, M.; Gemma, S.
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Pharmacophore modeling for qualitative prediction of antiestrogenic activity | 1-gen-2009 | Brogi, S.; Kladi, M.; Vagias, C.; Papazafiri, P.; Roussis, V.; Tafi, A. | |
| Pharmacophore modeling: A continuously evolving tool for computational drug design | 1-gen-2009 | Tafi, Andrea; Bellucci, Luca; Brogi, Simone; Caporuscio, Fabiana; Olla, Stefania | |
| Tetrahydrofuran acetogenins from Laurencia glandulifera | 1-gen-2009 | Kladi, M.; Vagias, C.; Papazafiri, P.; Brogi, S.; Tafi, A.; Roussis, V. | |
| Three-dimensional quantitative structure-selectivity relationships analysis guided rational design of a highly selective ligand for the cannabinoid receptor 2 | 1-gen-2011 | Brogi, S.; Corelli, F.; Di Marzo, V.; Ligresti, A.; Mugnaini, C.; Pasquini, S.; Tafi, A. | |
| Synthesis and antiplasmodial activity of bicyclic dioxanes as simplified dihydroplakortin analogues | 1-gen-2011 | Gemma, S.; Kunjir, S.; Sanna Coccone, S.; Brindisi, M.; Moretti, V.; Brogi, S.; Novellino, E.; Basilico, N.; Parapini, S.; Taramelli, D.; Campiani, G.; Butini, S. | |
| PROKINETICIN 1 RECEPTOR AGONISTS AND THEIR USES | 1-gen-2012 | Desaubry, Laurent; Desaubry, Gunsel Canan; Boulberdaa, Mounia; Kindo, Michel; Tafi, Andrea; Brogi, Simone; Urayama, Kyoji; Ribeiro, Nigel | |
| Optimization of 4-aminoquinoline/clotrimazole-based hybrid antimalarials: Further structure-activity relationships, in vivo studies, and preliminary toxicity profiling | 1-gen-2012 | Gemma, S.; Camodeca, C.; Sanna Coccone, S.; Joshi, B. P.; Bernetti, M.; Moretti, V.; Brogi, S.; De Marcos, M. C. B.; Savini, L.; Taramelli, D.; Basilico, N.; Parapini, S.; Rottmann, M.; Brun, R.; Lamponi, S.; Caccia, S.; Guiso, G.; Summers, R. L.; Martin, R. E.; Saponara, S.; Gorelli, B.; Novellino, E.; Campiani, G.; Butini, S. | |
| Characterization of COR627 and COR628, two novel positive allosteric modulators of the GABA B receptor | 1-gen-2012 | Castelli, M. P.; Casu, A.; Casti, P.; Lobina, C.; Carai, M. A. M.; Colombo, G.; Solinas, M.; Giunta, D.; Mugnaini, C.; Pasquini, S.; Tafi, A.; Brogi, S.; Gessa, G. L.; Corelli, F. | |
| Quinolylhydrazones as novel inhibitors of Plasmodium falciparum serine protease PfSUB1 | 1-gen-2012 | Gemma, S.; Giovani, S.; Brindisi, M.; Tripaldi, P.; Brogi, S.; Savini, L.; Fiorini, I.; Novellino, E.; Butini, S.; Campiani, G.; Penzo, M.; Blackman, M. J. | |
| Design, synthesis, and pharmacological characterization of indol-3-ylacetamides, indol-3-yloxoacetamides, and indol-3-ylcarboxamides: Potent and selective CB2 cannabinoid receptor inverse agonists | 1-gen-2012 | Pasquini, S.; Mugnaini, C.; Ligresti, A.; Tafi, A.; Brogi, S.; Falciani, C.; Pedani, V.; Pesco, N.; Guida, F.; Luongo, L.; Varani, K.; Borea, P. A.; Maione, S.; Di Marzo, V.; Corelli, F. | |
| Mimicking the intramolecular hydrogen bond: Synthesis, biological evaluation, andmolecular modeling of benzoxazines and quinazolines as potential antimalarial agents | 1-gen-2012 | Gemma, S.; Camodeca, C.; Brindisi, M.; Brogi, S.; Kukreja, G.; Kunjir, S.; Gabellieri, E.; Lucantoni, L.; Habluetzel, A.; Taramelli, D.; Basilico, N.; Gualdani, R.; Tadini-Buoninsegni, F.; Bartolommei, G.; Moncelli, M. R.; Martin, R. E.; Summers, R. L.; Lamponi, S.; Savini, L.; Fiorini, I.; Valoti, M.; Novellino, E.; Campiani, G.; Butini, S. | |
| Synthesis and structure-activity relationship studies in serotonin 5-HT1A receptor agonists based on fused pyrrolidone scaffolds | 1-gen-2013 | Cappelli, A.; Manini, M.; Valenti, S.; Castriconi, F.; Giuliani, G.; Anzini, M.; Brogi, S.; Butini, S.; Gemma, S.; Campiani, G.; Giorgi, G.; Mennuni, L.; Lanza, M.; Giordani, A.; Caselli, G.; Letari, O.; Makovec, F. | |
| Multifunctional cholinesterase and amyloid beta fibrillization modulators. Synthesis and biological investigation | 1-gen-2013 | Butini, S.; Brindisi, M.; Brogi, S.; Maramai, S.; Guarino, E.; Panico, A.; Saxena, A.; Chauhan, V.; Colombo, R.; Verga, L.; De Lorenzi, E.; Bartolini, M.; Andrisano, V.; Novellino, E.; Campiani, G.; Gemma, S. | |
| The structural evolution of β-secretase inhibitors: A focus on the development of small-molecule inhibitors | 1-gen-2013 | Butini, S.; Brogi, S.; Novellino, E.; Campiani, G.; Ghosh, A. K.; Brindisi, M.; Gemma, S. | |
| A stereoselective approach to peptidomimetic BACE1 inhibitors | 1-gen-2013 | Butini, S.; Gabellieri, E.; Brindisi, M.; Giovani, S.; Maramai, S.; Kshirsagar, G.; Guarino, E.; Brogi, S.; La Pietra, V.; Giustiniano, M.; Marinelli, L.; Novellino, E.; Campiani, G.; Cappelli, A.; Gemma, S. | |
| NOVEL ANALGESIC/ANTI-INFLAMMATORY AGENTS: 1,5-DIARYLPYRROLE NITROOXYALKYL ETHERS AND RELATED COMPOUNDS AS CYCLOOXYGENASE-2 INHIBITING NITRIC OXIDE DONORS | 1-gen-2013 | M., Anzini; A., DI CAPUA; S., Valenti; Brogi, Simone; M., Rovini; G., Giuliani; A., Cappelli; S., Vomero; L., Chiasserini; A., Sega; G., Poce; G., Giorgi; Calderone, Vincenzo; Martelli, Alma; Testai, Lara; L., Sautebin; A., Rossi; S., Pace; C., Ghelardini; L., DI CESARE MANNELLI; V., Benetti; A., Giordani; P., Anzellotti; M., Dovizio; P., Patrignani; M., Biava | |
| 3D-QSAR using pharmacophore-based alignment and virtual screening for discovery of novel MCF-7 cell line inhibitors | 1-gen-2013 | Brogi, S.; Papazafiri, P.; Roussis, V.; Tafi, A. | |
| 0365: Non-peptidic prokineticin receptor 1 agonist as a novel cardioprotective therapeutic | 1-gen-2014 | Gasser, Adeline; Nishi, Toshihide; Nguyen, Thu Lan; Urayama, Kyoji; Kurose, Hitoshi; Charavin, Marine; Brogi, Simone; Tafi, Andrea; Desaubry, Laurent; Nebigil, Canan | |
| Discovery of GPCR ligands for probing signal transduction pathways | 1-gen-2014 | Brogi, S.; Tafi, A.; Desaubry, L.; Nebigil, C. G. | |
| Disease-modifying anti-Alzheimer's drugs: Inhibitors of human cholinesterases interfering with β-amyloid aggregation | 1-gen-2014 | Brogi, S.; Butini, S.; Maramai, S.; Colombo, R.; Verga, L.; Lanni, C.; De Lorenzi, E.; Lamponi, S.; Andreassi, M.; Bartolini, M.; Andrisano, V.; Novellino, E.; Campiani, G.; Brindisi, M.; Gemma, S. |
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