Sfoglia per Autore
New Multitarget Approaches in the War Against Glioblastoma: A Mini-Perspective
2018-01-01 Sestito, Simona; Runfola, Massimiliano; Tonelli, Marco; Chiellini, Grazia; Rapposelli, Simona
Dual PDK1/aurora kinase a inhibitors reduce pancreatic cancer cell proliferation and colony formation
2019-01-01 Casari, I.; Domenichini, A.; Sestito, S.; Capone, E.; Sala, G.; Rapposelli, S.; Falasca, M.
Design and synthesis of H2S-donor hybrids: A new treatment for Alzheimer's disease?
2019-01-01 Sestito, S.; Pruccoli, L.; Runfola, M.; Citi, V.; Martelli, A.; Saccomanni, G.; Calderone, V.; Tarozzi, A.; Rapposelli, S.
Preclinical validation of 3-phosphoinositide-dependent protein kinase 1 inhibition in pancreatic cancer
2019-01-01 Emmanouilidi, A.; Fyffe, C. A.; Ferro, R.; Edling, C. E.; Capone, E.; Sestito, S.; Rapposelli, S.; Lattanzio, R.; Iacobelli, S.; Sala, G.; Maffucci, T.; Falasca, M.
Memantine prodrug as a new agent for alzheimer’s disease
2019-01-01 Sestito, S.; Daniele, S.; Pietrobono, D.; Citi, V.; Bellusci, L.; Chiellini, G.; Calderone, V.; Martini, C.; Rapposelli, S.
Multi-targeted ChEI-copper chelating molecules as neuroprotective agents
2019-01-01 Sestito, Simona; Wang, Shengnan; Chen, Qiuhe; Lu, Junfeng; Bertini, Simone; Pomelli, Christian; Chiellini, Grazia; He, Xixin; Pi, Rongbiao; Rapposelli, Simona
A patent update on PDK1 inhibitors (2015-present)
2019-01-01 Sestito, S.; Rapposelli, S.
Epibatidine: A Promising Natural Alkaloid in Health
2019-01-01 Salehi, Bahare; Sestito, Simona; Rapposelli, Simona; Peron, Gregorio; Calina, Daniela; Sharifi-Rad, Mehdi; Sharopov, Farukh; Martins, Natália; Sharifi-Rad, Javad
3-Iodothyronamine and Derivatives: New Allies Against Metabolic Syndrome?
2020-01-01 Rutigliano, Grazia; Bandini, Lavinia; Sestito, Simona; Chiellini, Grazia
SUN-717 SG-2 a Novel Multi-Target Directed Ligand (MTDL) for the Treatment of Neurodegenerative Diseases (NDDS)
2020-01-01 Chiellini, Grazia; Rapposelli, Simona; Origlia, Nicola; Santucci, Filippo; Bandini, Lavinia; Runfola, Massimiliano; Sestito, Simona
Areca catechu—From farm to food and biomedical applications
2020-01-01 Salehi, B.; Konovalov, D. A.; Fru, P.; Kapewangolo, P.; Peron, G.; Ksenija, M. S.; Cardoso, S. M.; Pereira, O. R.; Nigam, M.; Nicola, S.; Pignata, G.; Rapposelli, S.; Sestito, S.; Anil Kumar, N. V.; de la Luz Cadiz-Gurrea, M.; Segura-Carretero, A.; P. Mishra, A.; Sharifi-Rad, M.; C. Cho, W.; Taheri, Y.; Setzer, W. N.; Sharifi-Rad, J.
Design, synthesis and biological evaluation of novel TRβ selective agonists sustained by ADME-toxicity analysis
2020-01-01 Runfola, Massimiliano; Sestito, Simona; Bellusci, Lorenza; La Pietra, Valeria; D'Amore, Vincenzo Maria; Kowalik, Marta Anna; Chiellini, Grazia; Gul, Sheraz; Perra, Andrea; Columbano, Amedeo; Marinelli, Luciana; Novellino, Ettore; Rapposelli, Simona
Selective Thyroid Hormone Receptor-Beta (TRβ) Agonists: New Perspectives for the Treatment of Metabolic and Neurodegenerative Disorders
2020-01-01 Saponaro, F.; Sestito, S.; Runfola, M.; Rapposelli, S.; Chiellini, G.
ACE2 in the era of SARS-CoV-2: controversies and novel perspectives
2020-01-01 Saponaro, Federica; Rutigliano, Grazia; Sestito, Simona; Bandini, Lavinia; Storti, Barbara; Bizzarri, Ranieri; Zucchi, Riccardo
Synthesis and pharmacological characterization of mitochondrial KATP channel openers with enhanced mitochondriotropic effects
2021-01-01 Testai, L.; Sestito, S.; Martelli, A.; Gorica, E.; Flori, L.; Calderone, V.; Rapposelli, S.
A comprehensive assessment of a new series of 5′,6′-difluorobenzotriazole-acrylonitrile derivatives as microtubule targeting agents (MTAs)
2021-01-01 Riu, F.; Sanna, L.; Ibba, R.; Piras, S.; Bordoni, V.; Scorciapino, M. A.; Lai, M.; Sestito, S.; Bagella, L.; Carta, A.
Abstract 2569: Development of potent dual PDK1/AurA kinase inhibitors for Ewing sarcoma therapy
2022-01-01 Riveiro, Maria Eugenia; Huguet, Samuel; Vazquez, Ramiro; Frapolli, Roberta; Puricelli, Guido; Sestito, Simona; Madar, Olivier; Rezai, Keyvan; Garau, Gianpiero; Rapposelli, Simona
Design, synthesis, and biological screening of a series of 4'-fluoro-benzotriazole-acrylonitrile derivatives as microtubule-destabilising agents (MDAs)
2022-01-01 Riu, Federico; Ibba, Roberta; Zoroddu, Stefano; Sestito, Simona; Lai, Michele; Piras, Sandra; Sanna, Luca; Bordoni, Valentina; Bagella, Luigi; Carta, Antonio
Multi-Target Mechanisms of Phytochemicals in Alzheimer's Disease: Effects on Oxidative Stress, Neuroinflammation and Protein Aggregation
2022-01-01 Sharifi-Rad, Javad; Rapposelli, Simona; Sestito, Simona; Herrera-Bravo, Jesús; Arancibia-Diaz, Alejandra; Salazar, Luis A; Yeskaliyeva, Balakyz; Beyatli, Ahmet; Leyva-Gómez, Gerardo; González-Contreras, Carlos; Gürer, Eda Sönmez; Martorell, Miquel; Calina, Daniela
Design, Synthesis, and In Vitro Evaluation of Novel 8-Amino-Quinoline Combined with Natural Antioxidant Acids
2022-01-01 Bacci, Andrea; Corsi, Francesca; Runfola, Massimiliano; Sestito, Simona; Piano, Ilaria; Manera, Clementina; Saccomanni, Giuseppe; Gargini, Claudia; Rapposelli, Simona
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| New Multitarget Approaches in the War Against Glioblastoma: A Mini-Perspective | 1-gen-2018 | Sestito, Simona; Runfola, Massimiliano; Tonelli, Marco; Chiellini, Grazia; Rapposelli, Simona | |
| Dual PDK1/aurora kinase a inhibitors reduce pancreatic cancer cell proliferation and colony formation | 1-gen-2019 | Casari, I.; Domenichini, A.; Sestito, S.; Capone, E.; Sala, G.; Rapposelli, S.; Falasca, M. | |
| Design and synthesis of H2S-donor hybrids: A new treatment for Alzheimer's disease? | 1-gen-2019 | Sestito, S.; Pruccoli, L.; Runfola, M.; Citi, V.; Martelli, A.; Saccomanni, G.; Calderone, V.; Tarozzi, A.; Rapposelli, S. | |
| Preclinical validation of 3-phosphoinositide-dependent protein kinase 1 inhibition in pancreatic cancer | 1-gen-2019 | Emmanouilidi, A.; Fyffe, C. A.; Ferro, R.; Edling, C. E.; Capone, E.; Sestito, S.; Rapposelli, S.; Lattanzio, R.; Iacobelli, S.; Sala, G.; Maffucci, T.; Falasca, M. | |
| Memantine prodrug as a new agent for alzheimer’s disease | 1-gen-2019 | Sestito, S.; Daniele, S.; Pietrobono, D.; Citi, V.; Bellusci, L.; Chiellini, G.; Calderone, V.; Martini, C.; Rapposelli, S. | |
| Multi-targeted ChEI-copper chelating molecules as neuroprotective agents | 1-gen-2019 | Sestito, Simona; Wang, Shengnan; Chen, Qiuhe; Lu, Junfeng; Bertini, Simone; Pomelli, Christian; Chiellini, Grazia; He, Xixin; Pi, Rongbiao; Rapposelli, Simona | |
| A patent update on PDK1 inhibitors (2015-present) | 1-gen-2019 | Sestito, S.; Rapposelli, S. | |
| Epibatidine: A Promising Natural Alkaloid in Health | 1-gen-2019 | Salehi, Bahare; Sestito, Simona; Rapposelli, Simona; Peron, Gregorio; Calina, Daniela; Sharifi-Rad, Mehdi; Sharopov, Farukh; Martins, Natália; Sharifi-Rad, Javad | |
| 3-Iodothyronamine and Derivatives: New Allies Against Metabolic Syndrome? | 1-gen-2020 | Rutigliano, Grazia; Bandini, Lavinia; Sestito, Simona; Chiellini, Grazia | |
| SUN-717 SG-2 a Novel Multi-Target Directed Ligand (MTDL) for the Treatment of Neurodegenerative Diseases (NDDS) | 1-gen-2020 | Chiellini, Grazia; Rapposelli, Simona; Origlia, Nicola; Santucci, Filippo; Bandini, Lavinia; Runfola, Massimiliano; Sestito, Simona | |
| Areca catechu—From farm to food and biomedical applications | 1-gen-2020 | Salehi, B.; Konovalov, D. A.; Fru, P.; Kapewangolo, P.; Peron, G.; Ksenija, M. S.; Cardoso, S. M.; Pereira, O. R.; Nigam, M.; Nicola, S.; Pignata, G.; Rapposelli, S.; Sestito, S.; Anil Kumar, N. V.; de la Luz Cadiz-Gurrea, M.; Segura-Carretero, A.; P. Mishra, A.; Sharifi-Rad, M.; C. Cho, W.; Taheri, Y.; Setzer, W. N.; Sharifi-Rad, J. | |
| Design, synthesis and biological evaluation of novel TRβ selective agonists sustained by ADME-toxicity analysis | 1-gen-2020 | Runfola, Massimiliano; Sestito, Simona; Bellusci, Lorenza; La Pietra, Valeria; D'Amore, Vincenzo Maria; Kowalik, Marta Anna; Chiellini, Grazia; Gul, Sheraz; Perra, Andrea; Columbano, Amedeo; Marinelli, Luciana; Novellino, Ettore; Rapposelli, Simona | |
| Selective Thyroid Hormone Receptor-Beta (TRβ) Agonists: New Perspectives for the Treatment of Metabolic and Neurodegenerative Disorders | 1-gen-2020 | Saponaro, F.; Sestito, S.; Runfola, M.; Rapposelli, S.; Chiellini, G. | |
| ACE2 in the era of SARS-CoV-2: controversies and novel perspectives | 1-gen-2020 | Saponaro, Federica; Rutigliano, Grazia; Sestito, Simona; Bandini, Lavinia; Storti, Barbara; Bizzarri, Ranieri; Zucchi, Riccardo | |
| Synthesis and pharmacological characterization of mitochondrial KATP channel openers with enhanced mitochondriotropic effects | 1-gen-2021 | Testai, L.; Sestito, S.; Martelli, A.; Gorica, E.; Flori, L.; Calderone, V.; Rapposelli, S. | |
| A comprehensive assessment of a new series of 5′,6′-difluorobenzotriazole-acrylonitrile derivatives as microtubule targeting agents (MTAs) | 1-gen-2021 | Riu, F.; Sanna, L.; Ibba, R.; Piras, S.; Bordoni, V.; Scorciapino, M. A.; Lai, M.; Sestito, S.; Bagella, L.; Carta, A. | |
| Abstract 2569: Development of potent dual PDK1/AurA kinase inhibitors for Ewing sarcoma therapy | 1-gen-2022 | Riveiro, Maria Eugenia; Huguet, Samuel; Vazquez, Ramiro; Frapolli, Roberta; Puricelli, Guido; Sestito, Simona; Madar, Olivier; Rezai, Keyvan; Garau, Gianpiero; Rapposelli, Simona | |
| Design, synthesis, and biological screening of a series of 4'-fluoro-benzotriazole-acrylonitrile derivatives as microtubule-destabilising agents (MDAs) | 1-gen-2022 | Riu, Federico; Ibba, Roberta; Zoroddu, Stefano; Sestito, Simona; Lai, Michele; Piras, Sandra; Sanna, Luca; Bordoni, Valentina; Bagella, Luigi; Carta, Antonio | |
| Multi-Target Mechanisms of Phytochemicals in Alzheimer's Disease: Effects on Oxidative Stress, Neuroinflammation and Protein Aggregation | 1-gen-2022 | Sharifi-Rad, Javad; Rapposelli, Simona; Sestito, Simona; Herrera-Bravo, Jesús; Arancibia-Diaz, Alejandra; Salazar, Luis A; Yeskaliyeva, Balakyz; Beyatli, Ahmet; Leyva-Gómez, Gerardo; González-Contreras, Carlos; Gürer, Eda Sönmez; Martorell, Miquel; Calina, Daniela | |
| Design, Synthesis, and In Vitro Evaluation of Novel 8-Amino-Quinoline Combined with Natural Antioxidant Acids | 1-gen-2022 | Bacci, Andrea; Corsi, Francesca; Runfola, Massimiliano; Sestito, Simona; Piano, Ilaria; Manera, Clementina; Saccomanni, Giuseppe; Gargini, Claudia; Rapposelli, Simona |
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