| Nome |
# |
|
Age-related macular degeneration: Current knowledge of zinc metalloproteinases involvement, file e0d6c92e-c96e-fcf8-e053-d805fe0aa794
|
361
|
|
Targeting Different Transthyretin Binding Sites with Unusual Natural Compounds, file e0d6c92b-d411-fcf8-e053-d805fe0aa794
|
264
|
|
Copper mediated amyloid-β binding to Transthyretin, file e0d6c92b-341c-fcf8-e053-d805fe0aa794
|
139
|
|
Synthesis and antiangiogenic activity study of new hop chalcone Xanthohumol analogues, file e0d6c92b-fccf-fcf8-e053-d805fe0aa794
|
127
|
|
N-(aroyl)-N-(arylmethyloxy)-α-alanines: selective inhibitors of aldose reductase, file e0d6c92d-0177-fcf8-e053-d805fe0aa794
|
122
|
|
Focus on Human Monoamine Transporter Selectivity. New Human DAT and NET Models, Experimental Validation, and SERT Affinity Exploration, file e0d6c930-3753-fcf8-e053-d805fe0aa794
|
120
|
|
Activation of carbonic anhydrases from human brain by amino alcohol oxime ethers: towards human carbonic anhydrase VII selective activators, file e0d6c92f-a409-fcf8-e053-d805fe0aa794
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117
|
|
Development of Thioaryl-Based Matrix Metalloproteinase-12 Inhibitors with Alternative Zinc-Binding Groups: Synthesis, Potentiometric, NMR, and Crystallographic Studies, file e0d6c930-b3d6-fcf8-e053-d805fe0aa794
|
114
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|
Synthesis and investigation of polyhydroxylated pyrrolidine derivatives as novel chemotypes showing dual activity as glucosidase and aldose reductase inhibitors, file e0d6c92d-cac0-fcf8-e053-d805fe0aa794
|
104
|
|
Application of PROTAC strategy to TTR-Aβ protein-protein interaction for the development of Alzheimer’s disease drugs, file e0d6c92f-f2aa-fcf8-e053-d805fe0aa794
|
103
|
|
Synthesis and cycloxygenase inhibitory properties of new naphthalene-methylsulfonamido, naphthalene-methylsulfonyl and tetrahydronaphthalen-methylsulfonamido compounds, file e0d6c928-f8fb-fcf8-e053-d805fe0aa794
|
98
|
|
Synthesis and structural analysis of halogen substituted fibril formation inhibitors of Human Transthyretin (TTR), file e0d6c928-f447-fcf8-e053-d805fe0aa794
|
91
|
|
Design and Synthesis of Ionic Liquid-Based Matrix Metalloproteinase Inhibitors (MMPIs): A Simple Approach to Increase Hydrophilicity and to Develop MMPI-Coated Gold Nanoparticles, file e0d6c92e-b34c-fcf8-e053-d805fe0aa794
|
90
|
|
Design, synthesis and biological evaluation of bifunctional inhibitors of membrane type 1 matrix metalloproteinase (MT1-MMP), file e0d6c92c-3326-fcf8-e053-d805fe0aa794
|
74
|
|
N-O-Isopropyl Sulfonamido-Based Hydroxamates as Matrix Metalloproteinase Inhibitors: Hit Selection and in Vivo Antiangiogenic Activity, file e0d6c92c-1404-fcf8-e053-d805fe0aa794
|
68
|
|
Sugar-Based Arylsulfonamide Carboxylates as Selective and Water-Soluble Matrix Metalloproteinase-12 Inhibitors, file e0d6c930-be7f-fcf8-e053-d805fe0aa794
|
64
|
|
Selective Arylsulfonamide Inhibitors of ADAM-17: Hit Optimization and Activity in Ovarian Cancer Cell Models, file e0d6c92c-3829-fcf8-e053-d805fe0aa794
|
58
|
|
Transthyretin complexes with curcumin and bromo-estradiol: Evaluation of solubilizing multicomponent mixtures, file e0d6c930-75ba-fcf8-e053-d805fe0aa794
|
55
|
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Natural compounds as inhibitors of transthyretin amyloidosis and neuroprotective agents: analysis of structural data for future drug design, file e0d6c92f-d628-fcf8-e053-d805fe0aa794
|
52
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|
Identification of histone deacetylase inhibitors with (arylidene)aminoxy scaffold active in uveal melanoma cell lines, file e0d6c92f-88ed-fcf8-e053-d805fe0aa794
|
49
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Oxy-imino saccharidic derivatives as a new structural class of aldose reductase inhibitors endowed with anti-oxidant activity, file e0d6c92e-ce70-fcf8-e053-d805fe0aa794
|
47
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|
Monoaryl derivatives as transthyretin fibril formation inhibitors: Design, synthesis, biological evaluation and structural analysis, file e0d6c92f-b2f4-fcf8-e053-d805fe0aa794
|
46
|
|
Natural marine and terrestrial compounds as modulators of matrix metalloproteinases-2 (MMP-2) and MMP-9 in alzheimer’s disease, file e0d6c930-19e5-fcf8-e053-d805fe0aa794
|
42
|
|
Bifunctional Inhibitors as a New Tool To Reduce Cancer Cell Invasion by Impairing MMP-9 Homodimerization, file e0d6c930-9f49-fcf8-e053-d805fe0aa794
|
30
|
|
Antioxidant quercetin 3-O-glycosylated plant flavonols contribute to Transthyretin stabilization, file a182499b-e154-42a3-81a8-556bc85ded20
|
20
|
|
Neuroglobin and neuroprotection: The role of natural and synthetic compounds in neuroglobin pharmacological induction, file e0d6c931-483b-fcf8-e053-d805fe0aa794
|
14
|
|
Physiological metals can induce conformational changes in transthyretin structure: Neuroprotection or misfolding induction?, file e0d6c931-8af1-fcf8-e053-d805fe0aa794
|
9
|
|
Resveratrol-like Compounds as SIRT1 Activators, file 5368dd67-69b0-46c7-a637-6a86fbfdbb48
|
8
|
|
null, file e0d6c92e-40cc-fcf8-e053-d805fe0aa794
|
8
|
|
Bifunctional Inhibitors as a New Tool To Reduce Cancer Cell Invasion by Impairing MMP-9 Homodimerization, file e0d6c928-ebfc-fcf8-e053-d805fe0aa794
|
7
|
|
Sugar-Based Arylsulfonamide Carboxylates as Selective and Water-Soluble Matrix Metalloproteinase-12 Inhibitors, file e0d6c928-f750-fcf8-e053-d805fe0aa794
|
7
|
|
Design and Synthesis of Ionic Liquid-Based Matrix Metalloproteinase Inhibitors (MMPIs): A Simple Approach to Increase Hydrophilicity and to Develop MMPI-Coated Gold Nanoparticles, file e0d6c92d-398d-fcf8-e053-d805fe0aa794
|
7
|
|
Carbonic anhydrase inhibitors and epilepsy: State of the art and future perspectives, file e0d6c931-96ad-fcf8-e053-d805fe0aa794
|
7
|
|
Compounds with a benzo [a]carbazole structure for use in the prevention and/or treatment of infectious diseases, file f0e23d74-e5d8-47c6-b567-7cac3b79ca7e
|
7
|
|
Pterostilbene fluorescent probes as potential tools for targeting neurodegeneration in biological applications, file 26a542e6-7aeb-4536-8dd9-94c04dddded3
|
6
|
|
Sugar-Based Arylsulfonamide Carboxylates as Selective and Water-Soluble Matrix Metalloproteinase-12 Inhibitors, file e0d6c928-f806-fcf8-e053-d805fe0aa794
|
6
|
|
X-ray crystal structure and activity of fluorenyl-based compounds as transthyretin fibrillogenesis inhibitors, file e0d6c928-fb15-fcf8-e053-d805fe0aa794
|
6
|
|
Nature-Inspired O-Benzyl Oxime-Based Derivatives as New Dual-Acting Agents Targeting Aldose Reductase and Oxidative Stress, file ab58a430-7842-415a-bb97-951dc4d3abbd
|
5
|
|
Arylsulfonamide inhibitors of aggrecanases as potential therapeutic agents for osteoarthritis: Synthesis and biological evaluation., file e0d6c926-35e2-fcf8-e053-d805fe0aa794
|
5
|
|
N-O-Isopropyl Sulfonamido-Based Hydroxamates as Matrix Metalloproteinase Inhibitors: Hit Selection and in Vivo Antiangiogenic Activity, file e0d6c926-9f90-fcf8-e053-d805fe0aa794
|
5
|
|
Comparison of helical scan and standard rotation methods in single-crystal X-ray data collection strategies, file e0d6c928-f444-fcf8-e053-d805fe0aa794
|
5
|
|
A new crystal form of human transthyretin obtained with a curcumin derived ligand, file e0d6c928-fe72-fcf8-e053-d805fe0aa794
|
5
|
|
Development of Thioaryl-Based Matrix Metalloproteinase-12 Inhibitors with Alternative Zinc-Binding Groups: Synthesis, Potentiometric, NMR, and Crystallographic Studies, file e0d6c92b-2b99-fcf8-e053-d805fe0aa794
|
5
|
|
Multifunctional Small Molecules as Potential Anti-Alzheimer's Disease Agents, file e0d6c931-893f-fcf8-e053-d805fe0aa794
|
5
|
|
Selective Arylsulfonamide Inhibitors of ADAM-17: Hit Optimization and Activity in Ovarian Cancer Cell Models, file e0d6c926-4074-fcf8-e053-d805fe0aa794
|
4
|
|
null, file e54202b2-7569-418c-afc7-ffe398a4a724
|
4
|
|
Omega-3 PUFAs as a Dietary Supplement in Senile Systemic Amyloidosis, file 6c87a06e-aa5e-48cf-8fd4-73d678076b6b
|
3
|
|
Pomegranate: A Source of Multifunctional Bioactive Compounds Potentially Beneficial in Alzheimer’s Disease, file bfd5e894-cd60-4ab8-bb0d-42d47bb2c7f4
|
3
|
|
Tafamidis (Vyndaqel): A Light for FAP Patients, file e0d6c926-45cb-fcf8-e053-d805fe0aa794
|
3
|
|
Exploring the binding of quercetin-3-O-metabolites with transthyretin, file e0d6c928-8628-fcf8-e053-d805fe0aa794
|
3
|
|
Selective Arylsulfonamide Inhibitors of ADAM-17: Hit Optimization and Activity in Ovarian Cancer Cell Models, file e0d6c926-4075-fcf8-e053-d805fe0aa794
|
2
|
|
Synthetic analogs of xanthohumol for use in the prevention and/or treatment of tumors, file e0d6c926-453b-fcf8-e053-d805fe0aa794
|
2
|
|
Transthyretin complexes with curcumin and bromo-estradiol: Evaluation of solubilizing multicomponent mixtures, file e0d6c928-fd4c-fcf8-e053-d805fe0aa794
|
2
|
|
Synthesis and antiangiogenic activity study of new hop chalcone Xanthohumol analogues, file e0d6c929-9007-fcf8-e053-d805fe0aa794
|
2
|
|
Targeting Different Transthyretin Binding Sites with Unusual Natural Compounds, file e0d6c92b-d413-fcf8-e053-d805fe0aa794
|
2
|
|
Monoaryl derivatives as transthyretin fibril formation inhibitors: Design, synthesis, biological evaluation and structural analysis, file e0d6c92f-eb90-fcf8-e053-d805fe0aa794
|
2
|
|
Identification of N-Acyl Hydrazones as New Non-Zinc-Binding MMP-13 Inhibitors by Structure-Based Virtual Screening Studies and Chemical Optimization, file 6b421000-2151-4c93-a072-09d3be5ed303
|
1
|
|
Synthesis and Evaluation of Monoaryl Derivatives as Transthyretin Fibril Formation Inhibitors, file 7fb19d01-dea3-4bdf-9f81-cbab80425e8b
|
1
|
|
Allosteric inhibition of (125I) ET-1 binding to ET(A) receptors by aldoxime and hydroxamic acid derivatives, file e0d6c926-323d-fcf8-e053-d805fe0aa794
|
1
|
|
null, file e0d6c926-fef9-fcf8-e053-d805fe0aa794
|
1
|
|
A new D2 dopamine receptor agonist allosterically modulates A2A adenosine receptor signalling by interacting with the A2A/D2 receptor heteromer, file e0d6c928-f65d-fcf8-e053-d805fe0aa794
|
1
|
|
Spirotetrahydronaphthalene analogues of sympathomimetic catecholamines. Synthesis and adrenergic activity of 5,6- and 6,7-dihydroxy-3,4-dihydrospiro(naphtalen-1(2H)-3'-piperidines), file e0d6c928-fb17-fcf8-e053-d805fe0aa794
|
1
|
|
Design, synthesis and biological evaluation of bifunctional inhibitors of membrane type 1 matrix metalloproteinase (MT1-MMP), file e0d6c92b-5717-fcf8-e053-d805fe0aa794
|
1
|
|
Synthesis and investigation of polyhydroxylated pyrrolidine derivatives as novel chemotypes showing dual activity as glucosidase and aldose reductase inhibitors, file e0d6c930-b596-fcf8-e053-d805fe0aa794
|
1
|
|
N-(aroyl)-N-(arylmethyloxy)-α-alanines: selective inhibitors of aldose reductase, file e0d6c930-d21a-fcf8-e053-d805fe0aa794
|
1
|
| Totale |
2.623 |