BERTINI, SIMONE Statistiche
BERTINI, SIMONE
DIPARTIMENTO DI FARMACIA
Enhanced Nutraceutical Properties of Extra Virgin Olive Oil Extract by Olive Leaf Enrichment
2023-01-01 Cuffaro, Doretta; Bertini, Simone; Macchia, Marco; Digiacomo, Maria
Identification of New GSK3β Inhibitors through a Consensus Machine Learning-Based Virtual Screening
2023-01-01 Galati, Salvatore; Di Stefano, Miriana; Bertini, Simone; Granchi, Carlotta; Giordano, Antonio; Gado, Francesca; Macchia, Marco; Tuccinardi, Tiziano; Poli, Giulio
Insights into the Antioxidant/Antiradical Effects and In Vitro Intestinal Permeation of Oleocanthal and Its Metabolites Tyrosol and Oleocanthalic Acid
2023-01-01 Cuffaro, Doretta; Pinto, Diana; Silva, Ana Margarida; Bertolini, Andrea; Bertini, Simone; Saba, Alessandro; Macchia, Marco; Rodrigues, Francisca; Digiacomo, Maria
Olive Mill Wastewater as Source of Polyphenols with Nutraceutical Properties
2023-01-01 Cuffaro, Doretta; Bertolini, Andrea; Bertini, Simone; Ricci, Claudio; Cascone, Maria Grazia; Danti, Serena; Saba, Alessandro; Macchia, Marco; Digiacomo, Maria
CB1 receptor binding sites for NAM and PAM: A first approach for studying, new n‑butyl‑diphenylcarboxamides as allosteric modulators
2022-01-01 Gado, F.; Ceni, C.; Ferrisi, R.; Sbrana, G.; Stevenson, L. A.; Macchia, M.; Pertwee, R. G.; Bertini, S.; Manera, C.; Ortore, G.
Content Variations in Oleocanthalic Acid and Other Phenolic Compounds in Extra-Virgin Olive Oil during Storage
2022-01-01 Esposito Salsano, Jasmine; Digiacomo, Maria; Cuffaro, Doretta; Bertini, Simone; Macchia, Marco
Machine Learning-Based Virtual Screening for the Identification of Cdk5 Inhibitors
2022-01-01 Di Stefano, Miriana; Galati, Salvatore; Ortore, Gabriella; Caligiuri, Isabella; Rizzolio, Flavio; Ceni, Costanza; Bertini, Simone; Bononi, Giulia; Granchi, Carlotta; Macchia, Marco; Poli, Giulio; Tuccinardi, Tiziano
Novel Potent and Selective Agonists of the GPR55 Receptor Based on the 3-Benzylquinolin-2(1H)-One Scaffold
2022-01-01 Ceni, Costanza; Benko, Michael J; Mohamed, Kawthar A; Poli, Giulio; Di Stefano, Miriana; Tuccinardi, Tiziano; Digiacomo, Maria; Valoti, Massimo; Laprairie, Robert B; Macchia, Marco; Bertini, Simone
Cannabinoid-Based Medicines and Multiple Sclerosis
2021-01-01 Manera, C.; Bertini, S.
Medicinal Chemistry approach, pharmacology and neuroprotective benefits of CB2R modulators in neurodegenerative diseases
2021-01-01 Ferrisi, R.; Ceni, C.; Bertini, S.; Macchia, M.; Manera, C.; Gado, F.
Variously substituted 2-oxopyridine derivatives: Extending the structure-activity relationships for allosteric modulation of the cannabinoid CB2 receptor
2021-01-01 Gado, F.; Mohamed, K. A.; Meini, S.; Ferrisi, R.; Bertini, S.; Digiacomo, M.; D'Andrea, F.; Stevenson, L. A.; Laprairie, R. B.; Pertwee, R. G.; Manera, C.
Modification on the 1,2-dihydro-2-oxo-pyridine-3-carboxamide core to obtain multi-target modulators of endocannabinoid system
2020-01-01 Gado, F.; Arena, C.; Fauci, C. L.; Reynoso-Moreno, I.; Bertini, S.; Digiacomo, M.; Meini, S.; Poli, G.; Macchia, M.; Tuccinardi, T.; Gertsch, J.; Chicca, A.; Manera, C.
Positive allosteric modulation of CB1 and CB2 cannabinoid receptors enhances the neuroprotective activity of a dual CB1R/CB2R orthosteric agonist
2020-01-01 Polini, B.; Cervetto, C.; Carpi, S.; Pelassa, S.; Gado, F.; Ferrisi, R.; Bertini, S.; Nieri, P.; Marcoli, M.; Manera, C.
PSNCBAM-1 analogs: Structural evolutions and allosteric properties at cannabinoid CB1 receptor
2020-01-01 Meini, S.; Gado, F.; Stevenson, L. A.; Digiacomo, M.; Saba, A.; Codini, S.; Macchia, M.; Pertwee, R. G.; Bertini, S.; Manera, C.
The endocannabinoid system dual-target ligand N-cycloheptyl-1,2-dihydro-5-bromo-1-(4-fluorobenzyl)-6-methyl-2-oxo-pyridine-3-carboxamide improves disease severity in a mouse model of multiple sclerosis
2020-01-01 Arena, C.; Gado, F.; Di Cesare Mannelli, L.; Cervetto, C.; Carpi, S.; Reynoso-Moreno, I.; Polini, B.; Vallini, E.; Chicca, S.; Lucarini, E.; Bertini, S.; D'Andrea, F.; Digiacomo, M.; Poli, G.; Tuccinardi, T.; Macchia, M.; Gertsch, J.; Marcoli, M.; Nieri, P.; Ghelardini, C.; Chicca, A.; Manera, C.
Allosteric modulators targeting cannabinoid cb1 and cb2 receptors: Implications for drug discovery
2019-01-01 Gado, F.; Meini, S.; Bertini, S.; Digiacomo, M.; Macchia, M.; Manera, C.
IDENTIFICATION OF NEW PSNCBAM-1 DERIVATIVES AS CB1 RECEPTOR ALLOSTERIC MODULATORS
2019-01-01 Meini, Serena; Bertini, Simone; Gado, Francesca; Digiacomo, Maria; Stevenson, Lesley A.; Macchia, Marco; Pertwee, Roger G.; Manera, Clementina
Identification of the first synthetic allosteric modulator of the CB2receptors and evidence of its efficacy for neuropathic pain relief
2019-01-01 Gado, Francesca; Di Cesare Mannelli, Lorenzo; Lucarini, Elena; Bertini, Simone; Cappelli, Elena; Digiacomo, Maria; Stevenson, Lesley A.; Macchia, Marco; Tuccinardi, Tiziano; Ghelardini, Carla; Pertwee, Roger G.; Manera, Clementina
Multi-targeted ChEI-copper chelating molecules as neuroprotective agents
2019-01-01 Sestito, Simona; Wang, Shengnan; Chen, Qiuhe; Lu, Junfeng; Bertini, Simone; Pomelli, Christian; Chiellini, Grazia; He, Xixin; Pi, Rongbiao; Rapposelli, Simona
NOVEL DIARYL UREA DERIVATIVES AS CANNABINOID TYPE 1 RECEPTOR ALLOSTERIC MODULATORS
2019-01-01 Meini, Serena; Bertini, Simone; Pertwee, Roger G.; Stevenson, Lesley A.; Gado, Francesca; Digiacomo, Maria; Macchia, Marco; Manera, Clementina
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Enhanced Nutraceutical Properties of Extra Virgin Olive Oil Extract by Olive Leaf Enrichment | 1-gen-2023 | Cuffaro, Doretta; Bertini, Simone; Macchia, Marco; Digiacomo, Maria | |
| Identification of New GSK3β Inhibitors through a Consensus Machine Learning-Based Virtual Screening | 1-gen-2023 | Galati, Salvatore; Di Stefano, Miriana; Bertini, Simone; Granchi, Carlotta; Giordano, Antonio; Gado, Francesca; Macchia, Marco; Tuccinardi, Tiziano; Poli, Giulio | |
| Insights into the Antioxidant/Antiradical Effects and In Vitro Intestinal Permeation of Oleocanthal and Its Metabolites Tyrosol and Oleocanthalic Acid | 1-gen-2023 | Cuffaro, Doretta; Pinto, Diana; Silva, Ana Margarida; Bertolini, Andrea; Bertini, Simone; Saba, Alessandro; Macchia, Marco; Rodrigues, Francisca; Digiacomo, Maria | |
| Olive Mill Wastewater as Source of Polyphenols with Nutraceutical Properties | 1-gen-2023 | Cuffaro, Doretta; Bertolini, Andrea; Bertini, Simone; Ricci, Claudio; Cascone, Maria Grazia; Danti, Serena; Saba, Alessandro; Macchia, Marco; Digiacomo, Maria | |
| CB1 receptor binding sites for NAM and PAM: A first approach for studying, new n‑butyl‑diphenylcarboxamides as allosteric modulators | 1-gen-2022 | Gado, F.; Ceni, C.; Ferrisi, R.; Sbrana, G.; Stevenson, L. A.; Macchia, M.; Pertwee, R. G.; Bertini, S.; Manera, C.; Ortore, G. | |
| Content Variations in Oleocanthalic Acid and Other Phenolic Compounds in Extra-Virgin Olive Oil during Storage | 1-gen-2022 | Esposito Salsano, Jasmine; Digiacomo, Maria; Cuffaro, Doretta; Bertini, Simone; Macchia, Marco | |
| Machine Learning-Based Virtual Screening for the Identification of Cdk5 Inhibitors | 1-gen-2022 | Di Stefano, Miriana; Galati, Salvatore; Ortore, Gabriella; Caligiuri, Isabella; Rizzolio, Flavio; Ceni, Costanza; Bertini, Simone; Bononi, Giulia; Granchi, Carlotta; Macchia, Marco; Poli, Giulio; Tuccinardi, Tiziano | |
| Novel Potent and Selective Agonists of the GPR55 Receptor Based on the 3-Benzylquinolin-2(1H)-One Scaffold | 1-gen-2022 | Ceni, Costanza; Benko, Michael J; Mohamed, Kawthar A; Poli, Giulio; Di Stefano, Miriana; Tuccinardi, Tiziano; Digiacomo, Maria; Valoti, Massimo; Laprairie, Robert B; Macchia, Marco; Bertini, Simone | |
| Cannabinoid-Based Medicines and Multiple Sclerosis | 1-gen-2021 | Manera, C.; Bertini, S. | |
| Medicinal Chemistry approach, pharmacology and neuroprotective benefits of CB2R modulators in neurodegenerative diseases | 1-gen-2021 | Ferrisi, R.; Ceni, C.; Bertini, S.; Macchia, M.; Manera, C.; Gado, F. | |
| Variously substituted 2-oxopyridine derivatives: Extending the structure-activity relationships for allosteric modulation of the cannabinoid CB2 receptor | 1-gen-2021 | Gado, F.; Mohamed, K. A.; Meini, S.; Ferrisi, R.; Bertini, S.; Digiacomo, M.; D'Andrea, F.; Stevenson, L. A.; Laprairie, R. B.; Pertwee, R. G.; Manera, C. | |
| Modification on the 1,2-dihydro-2-oxo-pyridine-3-carboxamide core to obtain multi-target modulators of endocannabinoid system | 1-gen-2020 | Gado, F.; Arena, C.; Fauci, C. L.; Reynoso-Moreno, I.; Bertini, S.; Digiacomo, M.; Meini, S.; Poli, G.; Macchia, M.; Tuccinardi, T.; Gertsch, J.; Chicca, A.; Manera, C. | |
| Positive allosteric modulation of CB1 and CB2 cannabinoid receptors enhances the neuroprotective activity of a dual CB1R/CB2R orthosteric agonist | 1-gen-2020 | Polini, B.; Cervetto, C.; Carpi, S.; Pelassa, S.; Gado, F.; Ferrisi, R.; Bertini, S.; Nieri, P.; Marcoli, M.; Manera, C. | |
| PSNCBAM-1 analogs: Structural evolutions and allosteric properties at cannabinoid CB1 receptor | 1-gen-2020 | Meini, S.; Gado, F.; Stevenson, L. A.; Digiacomo, M.; Saba, A.; Codini, S.; Macchia, M.; Pertwee, R. G.; Bertini, S.; Manera, C. | |
| The endocannabinoid system dual-target ligand N-cycloheptyl-1,2-dihydro-5-bromo-1-(4-fluorobenzyl)-6-methyl-2-oxo-pyridine-3-carboxamide improves disease severity in a mouse model of multiple sclerosis | 1-gen-2020 | Arena, C.; Gado, F.; Di Cesare Mannelli, L.; Cervetto, C.; Carpi, S.; Reynoso-Moreno, I.; Polini, B.; Vallini, E.; Chicca, S.; Lucarini, E.; Bertini, S.; D'Andrea, F.; Digiacomo, M.; Poli, G.; Tuccinardi, T.; Macchia, M.; Gertsch, J.; Marcoli, M.; Nieri, P.; Ghelardini, C.; Chicca, A.; Manera, C. | |
| Allosteric modulators targeting cannabinoid cb1 and cb2 receptors: Implications for drug discovery | 1-gen-2019 | Gado, F.; Meini, S.; Bertini, S.; Digiacomo, M.; Macchia, M.; Manera, C. | |
| IDENTIFICATION OF NEW PSNCBAM-1 DERIVATIVES AS CB1 RECEPTOR ALLOSTERIC MODULATORS | 1-gen-2019 | Meini, Serena; Bertini, Simone; Gado, Francesca; Digiacomo, Maria; Stevenson, Lesley A.; Macchia, Marco; Pertwee, Roger G.; Manera, Clementina | |
| Identification of the first synthetic allosteric modulator of the CB2receptors and evidence of its efficacy for neuropathic pain relief | 1-gen-2019 | Gado, Francesca; Di Cesare Mannelli, Lorenzo; Lucarini, Elena; Bertini, Simone; Cappelli, Elena; Digiacomo, Maria; Stevenson, Lesley A.; Macchia, Marco; Tuccinardi, Tiziano; Ghelardini, Carla; Pertwee, Roger G.; Manera, Clementina | |
| Multi-targeted ChEI-copper chelating molecules as neuroprotective agents | 1-gen-2019 | Sestito, Simona; Wang, Shengnan; Chen, Qiuhe; Lu, Junfeng; Bertini, Simone; Pomelli, Christian; Chiellini, Grazia; He, Xixin; Pi, Rongbiao; Rapposelli, Simona | |
| NOVEL DIARYL UREA DERIVATIVES AS CANNABINOID TYPE 1 RECEPTOR ALLOSTERIC MODULATORS | 1-gen-2019 | Meini, Serena; Bertini, Simone; Pertwee, Roger G.; Stevenson, Lesley A.; Gado, Francesca; Digiacomo, Maria; Macchia, Marco; Manera, Clementina |