| Nome |
# |
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Oleocanthal and oleacein contribute to the in vitro therapeutic potential of extra virgin oil-derived extracts in non-melanoma skin cancer, file e0d6c92b-9815-fcf8-e053-d805fe0aa794
|
625
|
|
Medicinal Chemistry approach, pharmacology and neuroprotective benefits of CB2R modulators in neurodegenerative diseases, file e0d6c931-882f-fcf8-e053-d805fe0aa794
|
420
|
|
Synthetic cannabinoid receptor agonists and antagonists: implication in CNS disorders, file e0d6c927-f364-fcf8-e053-d805fe0aa794
|
399
|
|
Allosteric modulators targeting cannabinoid cb1 and cb2 receptors: Implications for drug discovery, file e0d6c92d-c701-fcf8-e053-d805fe0aa794
|
276
|
|
Cytotoxic Activity of Oleocanthal Isolated from Virgin Olive Oil on Human Melanoma Cells, file e0d6c92b-8489-fcf8-e053-d805fe0aa794
|
232
|
|
Beyond the Direct Activation of Cannabinoid Receptors: New Strategies to Modulate the Endocannabinoid System in CNS-Related Diseases, file e0d6c92b-b1c8-fcf8-e053-d805fe0aa794
|
219
|
|
Immuno-Modulatory Properties of a Quinolin-2-(1H)-on-3-Carboxamide Derivative: Relevance in Multiple Sclerosis, file e0d6c92b-b601-fcf8-e053-d805fe0aa794
|
215
|
|
Synthesis and pharmacological evaluation of new biphenylic derivatives as CB2 receptor ligands, file e0d6c92b-be0d-fcf8-e053-d805fe0aa794
|
181
|
|
Sulfonamido-derivatives of unsubstituted carbazoles as BACE1 inhibitors, file e0d6c92b-83c0-fcf8-e053-d805fe0aa794
|
163
|
|
Identification of the first synthetic allosteric modulator of the CB2receptors and evidence of its efficacy for neuropathic pain relief, file e0d6c92b-9d36-fcf8-e053-d805fe0aa794
|
161
|
|
Synthesis, biological activity and molecular modeling of new biphenylic carboxamides as potent and selective CB2 receptor ligands, file e0d6c92b-7b1f-fcf8-e053-d805fe0aa794
|
157
|
|
Discovery of 1,5-Diphenylpyrazole-3-Carboxamide Derivatives as Potent, Reversible, and Selective Monoacylglycerol Lipase (MAGL) Inhibitors, file e0d6c92b-d355-fcf8-e053-d805fe0aa794
|
133
|
|
4-Aryliden-2-methyloxazol-5(4H)-one as a new scaffold for selective reversible MAGL inhibitors, file e0d6c927-3706-fcf8-e053-d805fe0aa794
|
132
|
|
Traditional Uses of Cannabinoids and New Perspectives in the Treatment of Multiple Sclerosis, file e0d6c92b-a98e-fcf8-e053-d805fe0aa794
|
110
|
|
miRNA Modulation and Antitumor Activity by the Extra-Virgin Olive Oil Polyphenol Oleacein in Human Melanoma Cells, file e0d6c92f-44f6-fcf8-e053-d805fe0aa794
|
101
|
|
Structural optimization of 4-chlorobenzoylpiperidine derivatives for the development of potent, reversible and selective monoacylglycerol lipase (MAGL) inhibitors, file e0d6c92b-7b0c-fcf8-e053-d805fe0aa794
|
98
|
|
Polypharmacological profile of 1,2-dihydro-2-oxo-pyridine-3-carboxamides in the endocannabinoid system, file e0d6c92b-a6b3-fcf8-e053-d805fe0aa794
|
90
|
|
The Extra-Virgin Olive Oil Polyphenols Oleocanthal and Oleacein Counteract Inflammation-Related Gene and miRNA Expression in Adipocytes by Attenuating NF-κB Activation, file e0d6c92d-bc8c-fcf8-e053-d805fe0aa794
|
87
|
|
Design, synthesis and preliminary evaluation of (18)F-labelled 1,8-naphthyridin- and quinolin-2-one-3-carboxamide derivatives for PET imaging of CB2 cannabinoid receptor, file e0d6c92b-79c2-fcf8-e053-d805fe0aa794
|
85
|
|
Positive allosteric modulation of CB1 and CB2 cannabinoid receptors enhances the neuroprotective activity of a dual CB1R/CB2R orthosteric agonist, file e0d6c92f-fbd9-fcf8-e053-d805fe0aa794
|
78
|
|
Application of An Improved HPLC-FL Method to Screen Serine Palmitoyl Transferase Inhibitors, file e0d6c929-f4c9-fcf8-e053-d805fe0aa794
|
75
|
|
A Proteomic Approach to Uncover Neuroprotective Mechanisms of Oleocanthal against Oxidative Stress, file e0d6c92b-8cb1-fcf8-e053-d805fe0aa794
|
74
|
|
Anti-proliferative properties and proapoptotic function of new CB2 selective cannabinoid receptor agonist in jurkat leukemia cells, file e0d6c92b-e36f-fcf8-e053-d805fe0aa794
|
74
|
|
Composition of health-promoting phenolic compounds in two extra-virgin olive oils and diversity of associated yeasts, file e0d6c92b-c3cd-fcf8-e053-d805fe0aa794
|
70
|
|
Diclofenac-Derived Hybrids for Treatment of Actinic Keratosis and Squamous Cell Carcinoma, file e0d6c92d-3592-fcf8-e053-d805fe0aa794
|
66
|
|
Immunomodulatory properties of 1,2-dihydro-4-hydroxy-2-oxo-1,8-naphthyridine-3-carboxamide derivative VL15, file e0d6c92b-c58c-fcf8-e053-d805fe0aa794
|
64
|
|
Development of an HPLC/UV assay for the evaluation of inhibitors of human recombinant monoacylglycerol lipase, file e0d6c92b-b32a-fcf8-e053-d805fe0aa794
|
63
|
|
Synthesis, in vitro and in vivo evaluation of 1,3,5-triazines as cannabinoid CB2 receptor agonists, file e0d6c930-c76d-fcf8-e053-d805fe0aa794
|
49
|
|
Novel analogs of PSNCBAM-1 as allosteric modulators of cannabinoid CB1 receptor, file e0d6c92b-9b4e-fcf8-e053-d805fe0aa794
|
38
|
|
Breakthroughs in medicinal chemistry: New targets and mechanisms, new drugs, new hopes-6, file e0d6c92e-b811-fcf8-e053-d805fe0aa794
|
35
|
|
Tyrosol-enriched tomatoes by diffusion across the fruit peel from a chitosan coating: a proposal of functional food, file 999d62d0-ca51-4781-bdbb-476284112b17
|
17
|
|
null, file e0d6c92f-fe20-fcf8-e053-d805fe0aa794
|
17
|
|
Variously substituted 2-oxopyridine derivatives: Extending the structure-activity relationships for allosteric modulation of the cannabinoid CB2 receptor, file 6d10c9a1-05f9-4054-b82a-0637c37bb088
|
14
|
|
null, file e0d6c92f-2275-fcf8-e053-d805fe0aa794
|
14
|
|
Synthesis and pharmacological evaluation of new biphenylic derivatives as CB2 receptor ligands, file e0d6c927-7891-fcf8-e053-d805fe0aa794
|
12
|
|
Synthesis, in vitro and in vivo evaluation of 1,3,5-triazines as cannabinoid CB2 receptor agonists, file e0d6c926-4a81-fcf8-e053-d805fe0aa794
|
11
|
|
New quinolone- and 1,8-naphthyridine-3-carboxamides as selective CB2 receptor agonists with anticancer and immuno-modulatory activity, file e0d6c92b-c60b-fcf8-e053-d805fe0aa794
|
11
|
|
New quinolone- and 1,8-naphthyridine-3-carboxamides as selective CB2 receptor agonists with anticancer and immuno-modulatory activity, file e0d6c930-d941-fcf8-e053-d805fe0aa794
|
11
|
|
The isoprenoid derivative N6-benzyladenosine (CM223) exerts antitumor effect in glioma patient-derived primary cells through the mevalonate pathway, file e0d6c92b-e52f-fcf8-e053-d805fe0aa794
|
10
|
|
1,2-Dihydro-2-oxopyridine-3-carboxamides: the C-5 substituent is responsible for functionality switch at CB2 cannabinoid receptor, file e0d6c926-44e8-fcf8-e053-d805fe0aa794
|
8
|
|
Cytotoxic Activity of Oleocanthal Isolated from Virgin Olive Oil on Human Melanoma Cells, file e0d6c92b-7af4-fcf8-e053-d805fe0aa794
|
8
|
|
Oleocanthalic acid from extra-virgin olive oil: Analysis, preparative isolation and radical scavenging activity, file e0d6c932-1f1e-fcf8-e053-d805fe0aa794
|
7
|
|
Sulfonamido-derivatives of unsubstituted carbazoles as BACE1 inhibitors, file e0d6c92b-7d41-fcf8-e053-d805fe0aa794
|
6
|
|
Oleocanthal and oleacein contribute to the in vitro therapeutic potential of extra virgin oil-derived extracts in non-melanoma skin cancer, file e0d6c92b-9817-fcf8-e053-d805fe0aa794
|
6
|
|
Polypharmacological profile of 1,2-dihydro-2-oxo-pyridine-3-carboxamides in the endocannabinoid system, file e0d6c92b-a6b2-fcf8-e053-d805fe0aa794
|
6
|
|
Determination of tramadol and metabolites by HPLC-FL and HPLC-MS/MS in urine of dogs, file e0d6c926-2279-fcf8-e053-d805fe0aa794
|
5
|
|
Synthesis, biological activity and molecular modeling of new biphenylic carboxamides as potent and selective CB2 receptor ligands, file e0d6c92b-a370-fcf8-e053-d805fe0aa794
|
5
|
|
Identification of the first synthetic allosteric modulator of the CB2receptors and evidence of its efficacy for neuropathic pain relief, file e0d6c92b-e67f-fcf8-e053-d805fe0aa794
|
5
|
|
null, file e0d6c92d-e3ca-fcf8-e053-d805fe0aa794
|
5
|
|
Immune-Modulation and Properties of Absorption and Blood Brain Barrier Permeability of 1,8-Naphthyridine Derivatives., file e0d6c926-40de-fcf8-e053-d805fe0aa794
|
4
|
|
4-Aryliden-2-methyloxazol-5(4H)-one as a new scaffold for selective reversible MAGL inhibitors, file e0d6c926-d05f-fcf8-e053-d805fe0aa794
|
4
|
|
Structural optimization of 4-chlorobenzoylpiperidine derivatives for the development of potent, reversible and selective monoacylglycerol lipase (MAGL) inhibitors, file e0d6c928-2b3f-fcf8-e053-d805fe0aa794
|
4
|
|
Attività antiproliferativa dell’oleocantale in cellule umane di melanoma cutaneo maligno., file e0d6c929-0ae9-fcf8-e053-d805fe0aa794
|
4
|
|
Discovery of 1,5-Diphenylpyrazole-3-Carboxamide Derivatives as Potent, Reversible, and Selective Monoacylglycerol Lipase (MAGL) Inhibitors, file e0d6c92a-54a9-fcf8-e053-d805fe0aa794
|
4
|
|
Identification of chemical byproducts in the radiofluorination of structurally complex aryliodonium salts, file e0d6c92b-aa52-fcf8-e053-d805fe0aa794
|
4
|
|
The endocannabinoid system dual-target ligand N-cycloheptyl-1,2-dihydro-5-bromo-1-(4-fluorobenzyl)-6-methyl-2-oxo-pyridine-3-carboxamide improves disease severity in a mouse model of multiple sclerosis, file e0d6c92f-5384-fcf8-e053-d805fe0aa794
|
4
|
|
CB2-Selective Cannabinoid Receptor Ligands: Synthesis, Pharmacological Evaluation, and Molecular Modeling Investigation of 1,8-Naphthyridin-2(1H)-one-3-carboxamides, file e0d6c926-4a80-fcf8-e053-d805fe0aa794
|
3
|
|
Design, synthesis and preliminary evaluation of (18)F-labelled 1,8-naphthyridin- and quinolin-2-one-3-carboxamide derivatives for PET imaging of CB2 cannabinoid receptor, file e0d6c92b-9e25-fcf8-e053-d805fe0aa794
|
3
|
|
Composition of health-promoting phenolic compounds in two extra-virgin olive oils and diversity of associated yeasts, file e0d6c92b-c02d-fcf8-e053-d805fe0aa794
|
3
|
|
Development of an HPLC/UV assay for the evaluation of inhibitors of human recombinant monoacylglycerol lipase, file e0d6c92b-d248-fcf8-e053-d805fe0aa794
|
3
|
|
Design, synthesis and biological evaluation of novel orthosteric-allosteric ligands of the cannabinoid receptor type 2 (CB2R), file 4df2cc93-2fae-4e84-93fa-a2e883a1120f
|
2
|
|
PSNCBAM-1 analogs: Structural evolutions and allosteric properties at cannabinoid CB1 receptor, file cb6d4da4-475b-46fa-a8a6-46fcf3c2f9c2
|
2
|
|
Rational design, synthesis and anti-proliferative properties of new CB2 selective cannabinoid receptor ligands: An investigation of the 1,8-naphthyridin-2(1H)-one scaffold, file e0d6c926-22cf-fcf8-e053-d805fe0aa794
|
2
|
|
A New 4-phenyl-1,8-naphthyridine Derivative Affects Carcinoma Cell Proliferation by Impairing Cell Cycle Progression and Inducing Apoptosis, file e0d6c926-31b8-fcf8-e053-d805fe0aa794
|
2
|
|
Simultaneous detection and quantification of parecoxib and valdecoxib in canine plasma by HPLC with spectrofluorimetric detection: development and validation of a new methodology., file e0d6c926-34e3-fcf8-e053-d805fe0aa794
|
2
|
|
Diversity of yeast community composition in olive oil from two different areas in Tuscany, file e0d6c929-bb7f-fcf8-e053-d805fe0aa794
|
2
|
|
Preliminary Investigation of a Novel 18F Radiopharmaceutical for Imaging CB2 Receptors in a SOD Mouse Model, file e0d6c931-6f1c-fcf8-e053-d805fe0aa794
|
2
|
|
The role of cannabinoids in bone metabolism: A new perspective for bone disorders, file e0d6c932-06c4-fcf8-e053-d805fe0aa794
|
2
|
|
CB1 receptor binding sites for NAM and PAM: A first approach for studying, new n‑butyl‑diphenylcarboxamides as allosteric modulators, file e0d6c932-0b1b-fcf8-e053-d805fe0aa794
|
2
|
|
Potential use of TG68 - A novel thyromimetic - for the treatment of non-alcoholic fatty liver (NAFLD)-associated hepatocarcinogenesis, file d3aff175-77a6-4881-b7ba-dd844209a932
|
1
|
|
1,8-Naphthyridin-4-one derivatives as new ligands of A2A adenosine receptors., file e0d6c926-2869-fcf8-e053-d805fe0aa794
|
1
|
|
EVALUATION OF TRAMADOL AND ITS MAIN METABOLITES IN HORSE PLASMA BY HPLC-FL AND LC-ESI-MS/MS TECHNIQUES, file e0d6c926-2eee-fcf8-e053-d805fe0aa794
|
1
|
|
Farmaci cardiaci e diuretici (Capitolo 34), file e0d6c926-a3f0-fcf8-e053-d805fe0aa794
|
1
|
|
Analgesici oppiodi: HPLC-FL e LC-UV-ESI-MS/MS per la determinazione simultanea del tramadolo e dei suoi metaboliti nel plasma di cavallo, file e0d6c928-916f-fcf8-e053-d805fe0aa794
|
1
|
|
Spirotetrahydronaphthalene analogues of sympathomimetic catecholamines. Synthesis and adrenergic activity of 5,6- and 6,7-dihydroxy-3,4-dihydrospiro(naphtalen-1(2H)-3'-piperidines), file e0d6c928-fb17-fcf8-e053-d805fe0aa794
|
1
|
|
Anti-proliferative activity of oleocanthal in human malignant cutaneous melanoma cells, file e0d6c929-1203-fcf8-e053-d805fe0aa794
|
1
|
|
Novel analogs of PSNCBAM-1 as allosteric modulators of cannabinoid CB1 receptor, file e0d6c92b-997b-fcf8-e053-d805fe0aa794
|
1
|
|
The isoprenoid derivative N6-benzyladenosine (CM223) exerts antitumor effect in glioma patient-derived primary cells through the mevalonate pathway, file e0d6c92b-a870-fcf8-e053-d805fe0aa794
|
1
|
|
Immunomodulatory properties of 1,2-dihydro-4-hydroxy-2-oxo-1,8-naphthyridine-3-carboxamide derivative VL15, file e0d6c92b-b41d-fcf8-e053-d805fe0aa794
|
1
|
|
Beyond the Direct Activation of Cannabinoid Receptors: New Strategies to Modulate the Endocannabinoid System in CNS-Related Diseases, file e0d6c92b-dc53-fcf8-e053-d805fe0aa794
|
1
|
|
Conformationally restrained β -blocking oxime ethers: synthesis and β -adrenergic properties of diastereoisomeric anti and syn 2-(5-isoxazolidinyl)ethanolamines, file e0d6c92e-b306-fcf8-e053-d805fe0aa794
|
1
|
|
Synthesis of glyco-conjugates of 1,2-dihydro-2-oxo-pyridine-3-carboxamides as new modulators of endocannabinoid system, file e0d6c92e-efe8-fcf8-e053-d805fe0aa794
|
1
|
|
Design, Synthesis, and In Vitro Evaluation of Novel 8-Amino-Quinoline Combined with Natural Antioxidant Acids, file fc9ef2e6-1522-44ee-b3c4-b002f2b1fe10
|
1
|
| Totale |
4.820 |