MANERA, CLEMENTINA
 Distribuzione geografica
Continente #
NA - Nord America 17.656
EU - Europa 9.293
AS - Asia 7.995
SA - Sud America 1.100
AF - Africa 281
OC - Oceania 18
Continente sconosciuto - Info sul continente non disponibili 6
Totale 36.349
Nazione #
US - Stati Uniti d'America 14.930
IT - Italia 2.810
CA - Canada 2.631
SG - Singapore 2.392
CN - Cina 2.210
FI - Finlandia 2.179
HK - Hong Kong 1.247
SE - Svezia 1.080
BR - Brasile 900
VN - Vietnam 727
DE - Germania 695
BG - Bulgaria 481
FR - Francia 401
TR - Turchia 390
PL - Polonia 369
GB - Regno Unito 305
KR - Corea 257
RU - Federazione Russa 236
UA - Ucraina 217
IN - India 210
AT - Austria 182
JP - Giappone 165
CH - Svizzera 94
BD - Bangladesh 63
CI - Costa d'Avorio 62
AR - Argentina 56
MX - Messico 51
IQ - Iraq 49
NL - Olanda 47
PK - Pakistan 46
NG - Nigeria 44
SA - Arabia Saudita 38
ES - Italia 37
MA - Marocco 37
GR - Grecia 36
BE - Belgio 32
ID - Indonesia 31
IL - Israele 28
EC - Ecuador 27
VE - Venezuela 25
ZA - Sudafrica 24
SN - Senegal 23
CO - Colombia 22
CZ - Repubblica Ceca 20
PH - Filippine 20
PE - Perù 19
EG - Egitto 18
TN - Tunisia 18
AU - Australia 17
IE - Irlanda 16
KE - Kenya 16
PY - Paraguay 16
UZ - Uzbekistan 16
UY - Uruguay 14
IR - Iran 11
NP - Nepal 11
CL - Cile 10
JM - Giamaica 10
AE - Emirati Arabi Uniti 9
AZ - Azerbaigian 9
DZ - Algeria 9
ET - Etiopia 9
RO - Romania 9
JO - Giordania 8
BO - Bolivia 7
CR - Costa Rica 7
KZ - Kazakistan 7
MY - Malesia 7
RS - Serbia 7
AL - Albania 6
EU - Europa 6
GE - Georgia 6
PS - Palestinian Territory 6
TT - Trinidad e Tobago 6
BJ - Benin 5
LT - Lituania 5
BY - Bielorussia 4
HU - Ungheria 4
LB - Libano 4
PA - Panama 4
PT - Portogallo 4
BA - Bosnia-Erzegovina 3
DM - Dominica 3
GA - Gabon 3
GY - Guiana 3
NI - Nicaragua 3
SK - Slovacchia (Repubblica Slovacca) 3
SY - Repubblica araba siriana 3
TH - Thailandia 3
ZM - Zambia 3
AM - Armenia 2
AO - Angola 2
BB - Barbados 2
BH - Bahrain 2
BW - Botswana 2
DK - Danimarca 2
DO - Repubblica Dominicana 2
HN - Honduras 2
KG - Kirghizistan 2
LI - Liechtenstein 2
Totale 36.313
Città #
Montreal 2.319
Helsinki 1.964
Woodbridge 1.518
Ashburn 1.423
Singapore 1.382
Ann Arbor 1.287
Hong Kong 1.222
Houston 1.000
Fairfield 950
Chandler 912
San Jose 863
Santa Clara 817
Dallas 666
Milan 553
Serra 533
Sofia 481
Shanghai 436
Beijing 414
Wilmington 364
Seattle 345
Hefei 337
Cambridge 308
New York 288
Jacksonville 270
Ottawa 246
Dong Ket 243
Seoul 241
Boardman 238
Izmir 235
Princeton 226
Los Angeles 221
Pisa 187
Lawrence 184
Lauterbourg 164
Medford 163
Vienna 154
Council Bluffs 152
Nanjing 148
Tokyo 144
Ho Chi Minh City 135
Munich 117
Des Moines 110
Istanbul 99
Marseille 99
Hanoi 95
Florence 92
Dearborn 86
Rome 84
Bern 82
Buffalo 79
Redondo Beach 77
São Paulo 73
Frankfurt am Main 65
Lucca 62
Abidjan 61
Columbus 61
London 60
San Diego 59
Boulder 54
The Dalles 54
Jüchen 53
Redwood City 49
Nanchang 45
Lagos 44
Orem 43
Turku 42
Warsaw 40
Fuzhou 39
Shenyang 39
Livorno 38
Pune 36
Ogden 35
Kunming 33
Brussels 31
Pistoia 30
Atlanta 29
Chicago 28
Jiaxing 28
San Francisco 28
Da Nang 27
Nuremberg 27
Pescara 27
Brooklyn 26
Falls Church 26
Rio de Janeiro 26
Hangzhou 25
Bremen 24
Casablanca 24
Guangzhou 24
Dakar 23
Düsseldorf 23
Grafing 23
Hyderabad 23
Norwalk 23
Belo Horizonte 22
Genoa 22
Baghdad 21
Brasília 20
Chennai 20
Denver 20
Totale 26.508
Nome #
Synthesis and a- and ß-adrenergic activity of spiromorpholines structurally related to sympathomimetic catecholamines 4.647
Cytotoxic Activity of Oleocanthal Isolated from Virgin Olive Oil on Human Melanoma Cells 374
4-Aryliden-2-methyloxazol-5(4H)-one as a new scaffold for selective reversible MAGL inhibitors 330
1,2,3-Triazolo[1,5-a][1,4]- and 1,2,3-Triazolo[1,5-a][1,5]benzodiazepine derivatives: synthesis and benzodiazepine receptor binding. 325
1,2,3-triazolo [4,5-d] pyridazines-V. Preparation and adenosine receptor binding of new 4-amino derivatives. 312
1,2,3-TRIAZOLO[4,5-e]-1,2,4-TRIAZOLO[3,4-c]PYRIMIDINES 283
1,2,3-Triazolo[4,5-d]-1,2,4-triazolo[4,3-b]pyridazines 264
1,2,3-Triazolo[1,5-a]quinoxalines: synthesis and binding to benzodiazepine and adenosine receptors 263
1,2,3-TRIAZOLO[4,5-D]PYRIDAZINES. PART VI. NEW 1-SUBSTITUTED-4-AMINO DERIVATIVES AND THEIR AFFINITY TOWARDS A1 AND A2 ADENOSINE RECEPTORS 256
Oleocanthal and oleacein contribute to the in vitro therapeutic potential of extra virgin oil-derived extracts in non-melanoma skin cancer 256
1,2,3-triazolo[4,5-d]pyridazines - Part VI. New 1-substituted-4-amino derivatives and their affinity towards A(1) and A(2A) adenosine receptors 250
Application of An Improved HPLC-FL Method to Screen Serine Palmitoyl Transferase Inhibitors 247
Identification of chemical byproducts in the radiofluorination of structurally complex aryliodonium salts 246
Diversity of yeast community composition in olive oil from two different areas in Tuscany 240
X-ray analisis, theoretical studies and a-adrenergic biopharmacological properties of 1-(2,5-dimethoxyphenyl)-2-aminoethanol and its morpholine analogue 239
New quinolone- and 1,8-naphthyridine-3-carboxamides as selective CB2 receptor agonists with anticancer and immuno-modulatory activity 232
1,8-Naphthyridin-4-one derivatives as new ligands of A2A adenosine receptors. 230
Beyond the Direct Activation of Cannabinoid Receptors: New Strategies to Modulate the Endocannabinoid System in CNS-Related Diseases 229
Identification of the first synthetic allosteric modulator of the CB2receptors and evidence of its efficacy for neuropathic pain relief 225
A NEW HPLC METHOD FOR THALIDOMIDE DETECTION IN HUMAN PLASMA 224
X-Ray analysis, theoretical studies and alfa-adrenergic biopharmacological properties of 1-(2,5-dimethoxyphenyl)-2-aminoethanol and its morpholine analogue. 224
Polypharmacological profile of 1,2-dihydro-2-oxo-pyridine-3-carboxamides in the endocannabinoid system 224
Novel analogs of PSNCBAM-1 as allosteric modulators of cannabinoid CB1 receptor 222
Synthesis and antitumor evaluation of 1,8-naphthyridine-2-(1H)-on-3carboxamide derivatives as CB2 selective agonists 221
Anti-proliferative activity of oleocanthal in human malignant cutaneous melanoma cells 221
Structural optimization of 4-chlorobenzoylpiperidine derivatives for the development of potent, reversible and selective monoacylglycerol lipase (MAGL) inhibitors 220
Discovery of 1,5-Diphenylpyrazole-3-Carboxamide Derivatives as Potent, Reversible, and Selective Monoacylglycerol Lipase (MAGL) Inhibitors 216
Tyrosol-enriched tomatoes by diffusion across the fruit peel from a chitosan coating: a proposal of functional food 215
1,2-Dihydro-2-oxopyridine-3-carboxamides: the C-5 substituent is responsible for functionality switch at CB2 cannabinoid receptor 210
Diclofenac-Derived Hybrids for Treatment of Actinic Keratosis and Squamous Cell Carcinoma 208
Synthesis and pharmacological evaluation of new biphenylic derivatives as CB2 receptor ligands 203
Synthesis, biological activity and molecular modeling of new biphenylic carboxamides as potent and selective CB2 receptor ligands 202
Design, Synthesis, and Biological Activity of New CB2 Receptor Ligands: from Orthosteric and Allosteric Modulators to Dualsteric/Bitopic Ligands 202
Rational design, synthesis, biological evaluation and labelling of selective cannabinoid CB2 receptor agonists as anticancer agents 201
CONFORMATIONALLY RESTRAINED ANALOGS OF SYMPATHOMIMETIC CATECHOLAMINES - SYNTHESIS AND ADRENERGIC ACTIVITY OF TETRAHYDROBENZOCYCLOHEPTENE DERIVATIVES 201
Composition of health-promoting phenolic compounds in two extra-virgin olive oils and diversity of associated yeasts 201
Allosteric modulators targeting cannabinoid cb1 and cb2 receptors: Implications for drug discovery 200
Development of an HPLC/UV assay for the evaluation of inhibitors of human recombinant monoacylglycerol lipase 199
The Extra-Virgin Olive Oil Polyphenols Oleocanthal and Oleacein Counteract Inflammation-Related Gene and miRNA Expression in Adipocytes by Attenuating NF-κB Activation 199
Design, Synthesis, and In Vitro Evaluation of Novel 8-Amino-Quinoline Combined with Natural Antioxidant Acids 198
Synthesis, in vitro and in vivo evaluation of 1,3,5-triazines as cannabinoid CB2 receptor agonists 197
New Insights into Bitopic Orthosteric/Allosteric Ligands of Cannabinoid Receptor Type 2 196
SYNTHESIS AND BETA-BLOCKING ACTIVITY OF (R,S)-(E)-OXIMEETHERS OF 2,3-DIHYDRO-1,8-NAPHTHYRIDINE AND 2,3-DIHYDROTHIOPYRANO[2,3-B]PYRIDINE: IDENTIFICATION OF BETA 3-ANTAGONISTS 196
Design, synthesis and preliminary evaluation of (18)F-labelled 1,8-naphthyridin- and quinolin-2-one-3-carboxamide derivatives for PET imaging of CB2 cannabinoid receptor 196
Sulfonamido-derivatives of unsubstituted carbazoles as BACE1 inhibitors 193
4-[6-(dansylamino)hexylamino]-7-methyl-2-phenyl-1,8-naphthyridine as a new potential fluorescent probe for studying A1-adenosine receptor 193
Modification on the 1,2-dihydro-2-oxo-pyridine-3-carboxamide core to obtain multi-target modulators of endocannabinoid system 192
Synthesis and In Vitro Characterization of Selective Cannabinoid CB2 Receptor Agonists: Biological Evaluation against Neuroblastoma Cancer Cells 191
CB2-Selective Cannabinoid Receptor Ligands: Synthesis, Pharmacological Evaluation, and Molecular Modeling Investigation of 1,8-Naphthyridin-2(1H)-one-3-carboxamides 190
A Proteomic Approach to Uncover Neuroprotective Mechanisms of Oleocanthal against Oxidative Stress 188
Conformationally Restrained Analogs of Sympathomimetic Catecholamines. Synthesis, Conformational Analysis, and Adrenergic Activity of Isochroman Derivatives 188
Conformational effects on the activity of drugs. 13. A revision of previously proposed models for the activation of alfa- and beta-adrenergic receptors 184
Synthetic cannabinoid receptor agonists and antagonists: implication in CNS disorders 183
Conformationally restrained beta-blocking oxime ethers: synthesis and beta-adrenergic properties of diastereoisomeric anti and syn 2-(5-isoxazolidinyl)ethanolamines 181
Role of the benzylic hydroxyl group of adrenergic cattecholamines in eliciting alpha-adrenergic activity. Synthesis and alpha1- and alpha2-adrenergic activity of 3-phenyl-3-piperidinols and of their desoxy analogs 180
Design, Synthesis and biological evaluation of new 1,8-naphthyridin-4(1h)-on-3-carboxamide and quinolin-4(1h)-on-3-carboxamide derivatives as CB2 selective agonists 180
Cannabinoid ReceptorActivation Induces Apoptosis through Tumor Necrosis Factor A Mediated Ceramide De novo Synthesis in Colon Cancer Cells, 180
Cannabinoid CB2/CB1 Selectivity. Receptor Modeling and Automated Docking Analysis 179
Stereochemistry and dynamics of the hydrobromide of 1-(aminomethyl)-5,6-dihydroxyisochroman, semirigid analogue of catecholamines 178
Immunomodulatory properties of 1,2-dihydro-4-hydroxy-2-oxo-1,8-naphthyridine-3-carboxamide derivative VL15 178
Modified RP-LC of Phenylthiocarbamyl Amino Acid Adducts in Plasma Acetonitrile Extracts using Multiple Internal Standards and Photo-Diode UV Detection. 178
Conformationally restrained β -blocking oxime ethers: synthesis and β -adrenergic properties of diastereoisomeric anti and syn 2-(5-isoxazolidinyl)ethanolamines 178
Immuno-Modulatory Properties of a Quinolin-2-(1H)-on-3-Carboxamide Derivative: Relevance in Multiple Sclerosis 177
Simultaneous detection and quantification of parecoxib and valdecoxib in canine plasma by HPLC with spectrofluorimetric detection: development and validation of a new methodology. 176
Conformationally restrained analogues of sympathomimetic catecholamines: Synthesis and adrenergic activity of 5,6- and 6,7-dihydroxy-3,4-dihydrospiro[naphthalen-1(2H)-2′,5′- morpholines] 174
Analgesici oppiodi: HPLC-FL e LC-UV-ESI-MS/MS per la determinazione simultanea del tramadolo e dei suoi metaboliti nel plasma di cavallo 173
Spiropiperidine strutturalmente correlate alle catecolamine. Sintesi ed attività recettoriale a- e ß-adrenergica 172
Allosteric modulation of the cannabinoid 2 receptor confers seizure resistance in mice 172
Synthesis and β-adrenergic properties of tetrahydronaphthalene analogs of dichloroisoproterenol 171
A2A receptor ligands: Past, present and future trends 169
Synthesis and evaluation of antihypertensive activity of 1,8-naphthyridine derivatives. Part X 168
Determination of water-soluble vitamins in multivitamin dietary supplements and in artichokes by micellar electrokinetic chromatography. 167
Synthesis and antiplatelet activity of some 3-phenyl-1,8-naphthyridine derivatives 166
PHARMACOKINETICS OF INTRAVENOUS AND INTRAMUSCULAR PARECOXIB IN HEALTHY BEAGLES 164
Role of the benzylic hydroxyl group of adrenergic catecholamines in eliciting a-adrenergic activity. Synthesis and a1- and a2-adrenergic activity of 3-phenyl-3-piperidinols and of their desoxy analogs 164
Study of the virucidal effect on Human Adenovirus type 5 of polysaccharides extracted from Arthrospira platensis and Dunaliella salina 163
1,8-naphthyridine derivatives potent and selective A1 adenosine antagonists 163
Effects on Immune Cells of a New 1,8-Naphthyridin-2-One Derivative and Its Analogues as Selective CB2 Agonists: Implications in Multiple Sclerosis 163
Rational design, synthesis and anti-proliferative properties of new CB2 selective cannabinoid receptor ligands: An investigation of the 1,8-naphthyridin-2(1H)-one scaffold 162
A New 4-phenyl-1,8-naphthyridine Derivative Affects Carcinoma Cell Proliferation by Impairing Cell Cycle Progression and Inducing Apoptosis 162
The cannabinoid CB2/CB1 selectivity. Homology modelling and automated docking analysis 161
Structure-based virtual screening: Identification of novel CB2 receptor ligands 161
Immune-Modulation and Properties of Absorption and Blood Brain Barrier Permeability of 1,8-Naphthyridine Derivatives. 161
ASSESSMENT OF THE PHARMACOKINETIC PROFILE OF TRAMADOL AND ITS MAIN METABOLITES IN PLASMA AND URINE FORM DOGS ORALLY ADMINISTERED WITH CONTRAMAL®, WITH OR WITHOUT FREEZE-DRIED GRAPE-FRUIT JUICE 160
Determination of tramadol and metabolites by HPLC-FL and HPLC-MS/MS in urine of dogs 160
HIGH PERFORMANCE LIQUID CHROMATOGRAPHIC DETERMINATION OF THALIDOMIDE IN PATIENTS AFFECTED BY HEPATOCELLULAR CARCINOMA 159
Synthesis and b-blocking activity of (R,S)-(E)-oximeethers of 2,3-dihydro-1,8-naphthyridine and 2,3-dihydrothiopyrano[2,3-b]-pyridine: potential antihypertensive agents. Part IX 159
The Interplay between Cannabinoid Receptors and Microglia in the Pathophysiology of Alzheimer's Disease 157
Unraveling the Protective Role of Oleocanthal and Its Oxidation Product, Oleocanthalic Acid, against Neuroinflammation 156
Design, synthesis, and biological evaluation of 1,8-naphthyridin-2(1H)-on-3-carboxamide, quinolin-2(1H)-on-3-carboxamide and 2-oxo-1,2-dihydropyridine-3-carboxamide derivatives as CB2 selective ligands 156
(E)-(ARYLMETHYLENEAMINOXY)ACETAMIDES AS ANALOGS OF NEUROLEPTIC BENZAMIDES - SYNTHESIS AND D-2-DOPAMINERGIC BINDING-AFFINITY 156
Conformationally restrained β -blocking oxime ethers. 4. Chiral 2-(3'-(5'-p-chlorophenyl)isoxazolidinyl)ethanolamines as conformationally restrained analogs of methyloxyiminomethyl (MOIM) β -adrenergic antagonists: synthesis, configuration and β -adrenergic properties 154
PHARMACOKINETICS OF DIFFERENT FORMULATIONS OF TRAMADOL IN THE HORSE 154
Synthesis and biological evaluation of 1,8-naphthyridine and quinoline derivatives as CB2 selective agonists 153
CB1 receptor binding sites for NAM and PAM: A first approach for studying, new n‑butyl‑diphenylcarboxamides as allosteric modulators 153
Carbazole-containing arylcarboxamides as BACE1 inhibitors 152
Synthesis of New 1,2,3-triazolo[1,2-a]benzotriazole derivatives or substituted 2,3-benzo-1,3a,6,6a-tetraazapentalenes. II” 151
IN VITRO METABOLISM OF TRAMADOL IN HORSES: PRELIMINARY DATA 151
Adenosine receptor modelling. A1/A2a selectivity 151
Sintesi e attività recettoriale adrenergica di analoghi tetraidronaftalenici di catecolamine simpatomimetiche 150
Totale 24.099
Categoria #
all - tutte 92.936
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 92.936


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20222.425 80 255 52 123 385 300 114 131 96 66 161 662
2022/20233.043 397 418 246 250 348 382 33 216 459 29 142 123
2023/20244.780 305 245 280 165 339 258 152 35 31 2.650 88 232
2024/20256.503 28 235 125 385 605 697 526 391 602 793 785 1.331
2025/20269.608 562 1.008 889 768 656 694 1.161 383 2.301 632 350 204
2026/202738 38 0 0 0 0 0 0 0 0 0 0 0
Totale 36.878