From the polar extracts of Origanum vulgare L. ssp. hirtum 19 compounds have been isolated. The structures and relative stereochemistry have been elucidated by spectroscopic analysis and determined as apigenin, luteolin, chrysoeriol, diosmetin, quercetin, eriodictyol, cosmoside, vicenin-2, caffeic acid, p-menth-3-ene-1,2-diol 1-O-â-glucopyranoside, thymoquinol 2-O-â-glucopyranoside, thymoquinol 5-O-ß-glucopyranoside, thymoquinol 2,5-O-ß-diglucopyranoside, 12-hydroxyjasmonic acid, 12-hydroxyjasmonic acid 12-O-â-glucopyranoside, lithospermic acid B, rosmarinic acid, 10-epi-lithospermic acid, and epi-lithospermic acid B. The three latter products display unusual stereochemistry of the 3,4-hydroxyphenyllactic acid unit(s), which to the authors’ best knowledge has never been reported before in similar compounds. Moreover, lithospermic acid B (and its stereoisomers), p-menth-3-ene-1,2-diol 1-O-ß-glucopyranoside, 12-hydroxyjasmonic acid, and 12-hydroxyjasmonic acid 12-O-ß-glucopyranoside were isolated for the first time from Origanum species.
|Autori:||KOUKOULITSA C; KARIOTI A; BERGONZI MC; PESCITELLI G; DI BARI L; SKALTSA H|
|Titolo:||Polar Constituents from the Aerial Parts of Origanum vulgare L. Ssp. hirtum Growing Wild in Greece|
|Anno del prodotto:||2006|
|Digital Object Identifier (DOI):||10.1021/jf061477i|
|Appare nelle tipologie:||1.1 Articolo in rivista|