In this article, Hu et al. show the importance, for gene regulation, of a genomic region harboring GWAS variants that affect type 2 diabetes risk at the STARD10 locus. They also identify FCHSD2 as a likely mediator of the effects of these variants on insulin secretion.

Chromatin 3D interaction analysis of the STARD10 locus unveils FCHSD2 as a regulator of insulin secretion

Hu M.;Marchetti P.;
2021-01-01

Abstract

In this article, Hu et al. show the importance, for gene regulation, of a genomic region harboring GWAS variants that affect type 2 diabetes risk at the STARD10 locus. They also identify FCHSD2 as a likely mediator of the effects of these variants on insulin secretion.
2021
Hu, M.; Cebola, I.; Carrat, G.; Jiang, S.; Nawaz, S.; Khamis, A.; Canouil, M.; Froguel, P.; Schulte, A.; Solimena, M.; Ibberson, M.; Marchetti, P.; Ca...espandi
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11568/1101871
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