While attempting to prepare 2,5-dithiacyclopentyl derivatives from N-acyl 5-fluoroindole by reaction with 1,2-ethanedithiol we discovered that, instead of the expected product, annelation occurred to give a tricyclic compound containing a 3,6-dithiaazepine ring. This reaction is stereoselective and was found to be general for N-acylindoles, not being affected by substituents on the indole ring.

A New, Stereoselective, Ring-Forming Reaction of 1,2-Ethanedithiol with N-Acylated Indoles

DI BARI, LORENZO;PESCITELLI, GENNARO
2007

Abstract

While attempting to prepare 2,5-dithiacyclopentyl derivatives from N-acyl 5-fluoroindole by reaction with 1,2-ethanedithiol we discovered that, instead of the expected product, annelation occurred to give a tricyclic compound containing a 3,6-dithiaazepine ring. This reaction is stereoselective and was found to be general for N-acylindoles, not being affected by substituents on the indole ring.
Tsotinis, A; Eleutheriades, A; DI BARI, Lorenzo; Pescitelli, Gennaro
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11568/111612
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