The phenobarbital-like enzyme inducer and tumor promoter of murine hepatocarcinogenesis, 1,4-bis[2-(3,5-dichloropyridoxy)]benzene has been assayed in short-term genotoxicity tests, i.e, the Salmonella mutagenicity test, micronucleus and chromosomal aberrations analysis in mouse bone marrow cells in vivo, DNA alkaline elution and DNA unwinding assays in mouse liver in vivo. All the assays performed proved negative.

Negative results of short-term genotoxicity tests with 1,4-bis[2-(3,5-dichloropyridyloxy)]benzene

BARALE, ROBERTO;
1990

Abstract

The phenobarbital-like enzyme inducer and tumor promoter of murine hepatocarcinogenesis, 1,4-bis[2-(3,5-dichloropyridoxy)]benzene has been assayed in short-term genotoxicity tests, i.e, the Salmonella mutagenicity test, micronucleus and chromosomal aberrations analysis in mouse bone marrow cells in vivo, DNA alkaline elution and DNA unwinding assays in mouse liver in vivo. All the assays performed proved negative.
Dragani, Ta; Barale, Roberto; Parodi, S; Taningher, M; Zucconi, D; Della Porta, G.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11568/11410
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