Bilateral striatal necrosis (BSN) is relatively rare and has been related to a wide array of causes, including nuclear and mitochondrial DNA mutations. We report the clinical vignette of a patient with a 37 year-history of generalized dystonia secondary to BSN associated with multiple mitochondrial DNA deletions of undefined origin. Globus pallidus interna deep brain stimulation produced sustained benefit, with predominant improvements in disability.
|Autori:||ANIELLO MS; MARTINO D; PETRUZZELLA V; ELEOPRA R; MANCUSO M; DELL'AGLIO R; CAVALLO M; SICILIANO G; DEFAZIO G|
|Titolo:||Bilateral striatal necrosis, dystonia and multiple mitochondrial DNA deletions: case study and effect of deep brain stimulation|
|Anno del prodotto:||2008|
|Appare nelle tipologie:||1.1 Articolo in rivista|