We report a patient with MELAS treated for 24 months with idebenone and riboflavin, during which no stroke-like episodes occurred. Moreover neurological symptoms clearly improved, and a recovery of brain MRI and EEG abnormalities was observed. We conclude that the combined treatment with idebenone and riboflavin may restore the metabolic impairment in MELAS, possibly improving the long-term prognosis in these patients.
|Autori:||Napolitano A; Salvetti S; Vista M; Lombardi V; Siciliano G; Giraldi C.|
|Titolo:||Long-term treatment with idebenone and riboflavin in a patient with MELAS.|
|Anno del prodotto:||2000|
|Appare nelle tipologie:||1.1 Articolo in rivista|