We report a patient with MELAS treated for 24 months with idebenone and riboflavin, during which no stroke-like episodes occurred. Moreover neurological symptoms clearly improved, and a recovery of brain MRI and EEG abnormalities was observed. We conclude that the combined treatment with idebenone and riboflavin may restore the metabolic impairment in MELAS, possibly improving the long-term prognosis in these patients.

Long-term treatment with idebenone and riboflavin in a patient with MELAS.

SICILIANO, GABRIELE;
2000-01-01

Abstract

We report a patient with MELAS treated for 24 months with idebenone and riboflavin, during which no stroke-like episodes occurred. Moreover neurological symptoms clearly improved, and a recovery of brain MRI and EEG abnormalities was observed. We conclude that the combined treatment with idebenone and riboflavin may restore the metabolic impairment in MELAS, possibly improving the long-term prognosis in these patients.
2000
Napolitano, A; Salvetti, S; Vista, M; Lombardi, V; Siciliano, Gabriele; Giraldi, C.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11568/163451
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