The polystyrene-supported bis-oxazoline 1 forms a complex with copper(II)triflate that is a highly effective catalyst for the heterogeneously catalyzed enantioselective Mukaiyama aldol reaction of silylthioketene acetals with methyl pyruvate (ca. 90 % yield, ca. 90 % ee). The catalyst can be recovered by simple filtration and reused several times without a decline in enantioselectivity.

An Insoluble Polymer-Bound Bis-Oxazoline Copper(II) Complex: A Highly Efficient Heterogeneous Catalyst for the Enantioselective Mukaiyama Aldol Reaction

MANDOLI, ALESSANDRO;PINI, DARIO;SALVADORI, PIERO
2001

Abstract

The polystyrene-supported bis-oxazoline 1 forms a complex with copper(II)triflate that is a highly effective catalyst for the heterogeneously catalyzed enantioselective Mukaiyama aldol reaction of silylthioketene acetals with methyl pyruvate (ca. 90 % yield, ca. 90 % ee). The catalyst can be recovered by simple filtration and reused several times without a decline in enantioselectivity.
S., Orlandi; Mandoli, Alessandro; Pini, Dario; Salvadori, Piero
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11568/177838
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