We report here the condensation of 2-amino-6-bromopyridine with ethyl 4-chloroacetoacetate in polyphosphoric acid. In this reaction, a mixture of the four possible dihalo-4H-pyrido[1,2-a]pyrimidin-4-ones 1-4 was obtained.
An unexpected result in the condensation of 2-amino-6-bromo-pyridine with ethyl 4-chloroacetoacetate: four dihalo-substituted pyrido[1,2-a]pyrimidin-4-ones as reaction products
SACCOMANNI, GIUSEPPE;MACCHIA, MARCO;
1999-01-01
Abstract
We report here the condensation of 2-amino-6-bromopyridine with ethyl 4-chloroacetoacetate in polyphosphoric acid. In this reaction, a mixture of the four possible dihalo-4H-pyrido[1,2-a]pyrimidin-4-ones 1-4 was obtained.File in questo prodotto:
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