Objective – To evaluate the tolerance of a continuous positive airway pressure (CPAP) mask in tranquilized dogs and compare PaO2 in arterial blood in dogs receiving oxygen with a regular face mask or CPAP mask set to maintain a pressure of 2.5 or 5 cmH2O. Design – Prospective, randomized clinical study. Setting – University teaching hospital. Animals – Sixteen client-owned dogs without evidence of cardiopulmonary disease were studied. Interventions – Eight animals were randomly assigned to each of 2 treatment groups: group A received 2.5cmH2O CPAP and group B received 5 cmH2O CPAP after first receiving oxygen (5 L/min) by a regular face mask. Animals were tranquilized with acepromazine 0.05 mg/kg, IV and morphine 0.2 mg/kg, IM. An arterial catheter was then placed to facilitate blood sampling for pHa, PaO2, and PaCO2 determinations before and after treatments. Direct mean arterial pressure, heart rate, respiratory rate, and temperature were also recorded after each treatment. Measurements and Main Results – CPAP administration was well tolerated by all animals. The mean arterial pressure, heart rate, respiratory rate, temperature, PaCO2, and pHa, did not differ at any time point between groups. Differences were seen in oxygenation; in group A, PaO2 significantly increased from a mean of 288.3 47.5mmHg with a standard mask to a mean of 390.3 65.5mmHg with the CPAP mask and in group B, PaO2 increased similarly from 325.0 70.5 to 425.2 63.4mmHg (Po0.05); no differences were detected between the 2 CPAP treatments. Conclusions – In healthy tranquilized dogs noninvasive CPAP is well tolerated and increases PaO2 above values obtained when using a regular face mask.
|Autori:||Briganti Angela; Melanie P; Portela Diego; Breghi Gloria; Mama Khursheed|
|Titolo:||Continuous positive airway pressure administered via face mask in tranquilized dogs|
|Anno del prodotto:||2010|
|Digital Object Identifier (DOI):||10.1111/j.1476-4431.2010.00579.x|
|Appare nelle tipologie:||1.1 Articolo in rivista|