Multimodality evoked potentials and pattern electroretinograms (PERGs) were performed in seventeen patients with histologically defined mitochondrial myopathy (MM). Brainstem auditory evoked potentials showed abnormalities in 47% and somatosensory evoked potentials in 76%. Visual evoked potentials were outside the normal range in 71%; PERGs exhibited a decreased amplitude or delayed P50 in 78%. These findings may be considered as an expression of impairment of the central nervous system in MM, even if the specific mechanism, 'structural' or 'functional', needs further investigation.
|Autori interni:||SARTUCCI, FERDINANDO|
|Autori:||Sartucci F; Rossi B; Tognoni G; Siciliano G; Guerrini V; Murri L|
|Titolo:||Evoked potentials in the evaluation of patients with mitochondrial myopathy|
|Anno del prodotto:||1993|
|Appare nelle tipologie:||1.1 Articolo in rivista|