The aim of this study was to evaluate the frequency and degree of peripheral neuropathy in 22 consecutive patients with mixed cryoglobulinemia, whether symptom-free or with subjective neurological symptoms. Electrophysiological investigations were carried out and a biopsy of the sural nerve was performed in six patients. Peripheral neuropathy of the lower limbs was demonstrated, which was mostly sensory and light or moderate in 86% of cases (19 patients). F-Wave and H-reflex recordings were found to be the most reliable methods; in 77% of cases, they were abnormal (17 patients). Using somatosensory evoked potentials, we were able to exclude simultaneous central nervous system involvement in 10 patients.

Cryoglobulinemic peripheral neuropathy: neurophysiologic evaluation in twenty-two patients.

CIOMPI, MARIA LAURA;SICILIANO, GABRIELE;SARTUCCI, FERDINANDO;
1996

Abstract

The aim of this study was to evaluate the frequency and degree of peripheral neuropathy in 22 consecutive patients with mixed cryoglobulinemia, whether symptom-free or with subjective neurological symptoms. Electrophysiological investigations were carried out and a biopsy of the sural nerve was performed in six patients. Peripheral neuropathy of the lower limbs was demonstrated, which was mostly sensory and light or moderate in 86% of cases (19 patients). F-Wave and H-reflex recordings were found to be the most reliable methods; in 77% of cases, they were abnormal (17 patients). Using somatosensory evoked potentials, we were able to exclude simultaneous central nervous system involvement in 10 patients.
Ciompi, MARIA LAURA; Marini, D; Siciliano, Gabriele; Melchiorre, D; Bazzichi, L; Sartucci, Ferdinando; Murri, L.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11568/201754
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