Histological examination of kidneys from mice experimentally infected with Toxocara canis embryonated eggs demonstrated he presence of a segmental or diffuse mesangioproliferative glomerulonephritis. Immunohistochemical studies established that renal alterations were associated with glomerular deposits of IgG, IgM and third component of complement (C3). These findings suggest that an immunomediated mechanism might possibly be involved in the genesis of kidney damage observed in mice infected with T. canis embryonated eggs.

Renal involvement in mice experimentally infected with Toxocara canis embryonated eggs

PAPINI, ROBERTO AMERIGO;MANCIANTI, FRANCESCA;ABRAMO, FRANCESCA;POLI, ALESSANDRO
1992

Abstract

Histological examination of kidneys from mice experimentally infected with Toxocara canis embryonated eggs demonstrated he presence of a segmental or diffuse mesangioproliferative glomerulonephritis. Immunohistochemical studies established that renal alterations were associated with glomerular deposits of IgG, IgM and third component of complement (C3). These findings suggest that an immunomediated mechanism might possibly be involved in the genesis of kidney damage observed in mice infected with T. canis embryonated eggs.
Casarosa, L; Papini, ROBERTO AMERIGO; Mancianti, Francesca; Abramo, Francesca; Poli, Alessandro
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11568/202582
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