Abstract Hemorrhagic cystitis is a common complication in hematopoietic stem cell transplant recipients. We report here a case of severe BKV-associated hemorrhagic cystitis who did not respond to intravenous cidofovir. Overt hematuria successfully resolved after a few days on hyperbaric oxygen and intravesical instillations of cidofovir, while BK viruria dropped after a few weeks and remained low. We review the literature for therapeutic options in hemorrhagic cystitis and try to explain how hyperbaric oxygen stimulates mucosal repair in the urinary bladder.

Hyperbaric oxygen therapy in BKV-associated hemorrhagic cystitis refractoty to intravenous and intravesical cidofovir:Case report and review of literature

MAGGI F;PISTOLESI, DONATELLA;PAPINESCHI, FEDERICO;GALIMBERTI, SARA;CECCHERINI-NELLI, LUCA;PETRINI, MARIO
2009

Abstract

Abstract Hemorrhagic cystitis is a common complication in hematopoietic stem cell transplant recipients. We report here a case of severe BKV-associated hemorrhagic cystitis who did not respond to intravenous cidofovir. Overt hematuria successfully resolved after a few days on hyperbaric oxygen and intravesical instillations of cidofovir, while BK viruria dropped after a few weeks and remained low. We review the literature for therapeutic options in hemorrhagic cystitis and try to explain how hyperbaric oxygen stimulates mucosal repair in the urinary bladder.
Focosi, D; Maggi, F; Pistolesi, Donatella; Benedetti, E; Papineschi, Federico; Galimberti, Sara; CECCHERINI-NELLI, Luca; Petrini, Mario
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11568/203620
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