EnglishA reversed-phase HPLC method has been developed for the urinary determination of mutagenic 2,4- and 2,6-toluendiamines. These amines are degradation products of polyurethane, a material used to cover textured silicone breast implants. FMOC-Cl was used as fluorescent derivatising agent in order to obtain a limit of detection of 15 ng/ml in urine. Pre-treatment of urine samples was by liquid/liquid extraction and urine specimens of patients after surgery were analysed.
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http://hdl.handle.net/11568/21235| Autori interni: | MACCHIA, MARCO |
| Autori: | DeLorenzi E; Massolini G; Macchia M; Caccialanza G |
| Titolo: | HPLC determination of urinary 2,4- and 2,6-toluendiamines as potential degradation products of polyurethane breast implants |
| Anno del prodotto: | 1995 |
| Digital Object Identifier (DOI): | 10.1007/BF02267801 |
| Appare nelle tipologie: | 1.1 Articolo in rivista |
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