The preparation of films from blends of collagen and poly(vinyl alcohol) is described and the transport properties of these films are evaluated. Different crosslinking procedures, dehydrothermal crosslinking and crosslinking by glutaraldehyde, have been used. The transport properties of these films have been studied using model solutes such as sodium chloride, vitamin B12 and bovine albumin. The results are compared with those obtained using commercial products such as Cuprophan® and poly(acrylonitrile) dialysis membranes. The aim of our study was to analyse the effects of different crosslinking methods and the effects of blending with poly(vinyl alcohol) upon the permeation characteristics of collagen-based membranes. The preparation of films from blends of collagen and poly(vinyl alcohol) is described and the transport properties of these films are evaluated. Different crosslinking procedures, dehydrothermal crosslinking and crosslinking by glutaraldehyde, have been used. The transport properties of these films have been studied using model solutes such as sodium chloride, vitamin B12 and bovine albumin. The results are compared with those obtained using commercial products such as Cuprophan(R) and poly(acrylonitrile) dialysis membranes. The aim of our study was to analyse the effects of different crosslinking methods and the effects of membranes.
Collagen-based bioartificial materials - Evaluation as membranes for extracorporeal blood purification
SEGGIANI, MAURIZIA;LAZZERI, LUIGI;CASCONE, MARIA GRAZIA;VITOLO, SANDRA;
1994-01-01
Abstract
The preparation of films from blends of collagen and poly(vinyl alcohol) is described and the transport properties of these films are evaluated. Different crosslinking procedures, dehydrothermal crosslinking and crosslinking by glutaraldehyde, have been used. The transport properties of these films have been studied using model solutes such as sodium chloride, vitamin B12 and bovine albumin. The results are compared with those obtained using commercial products such as Cuprophan® and poly(acrylonitrile) dialysis membranes. The aim of our study was to analyse the effects of different crosslinking methods and the effects of blending with poly(vinyl alcohol) upon the permeation characteristics of collagen-based membranes. The preparation of films from blends of collagen and poly(vinyl alcohol) is described and the transport properties of these films are evaluated. Different crosslinking procedures, dehydrothermal crosslinking and crosslinking by glutaraldehyde, have been used. The transport properties of these films have been studied using model solutes such as sodium chloride, vitamin B12 and bovine albumin. The results are compared with those obtained using commercial products such as Cuprophan(R) and poly(acrylonitrile) dialysis membranes. The aim of our study was to analyse the effects of different crosslinking methods and the effects of membranes.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
