Mebenzadole was tested for in vivo effect on the eggs of B. transfuga recovered from polar bears treated with the drug. A marked reduction of the number of eggs that developed to the larval stage was observed. The pre-treatment percentage of incubated eggs that developed to the larval stage was 80 %-92 %. On day 1, after treatment was starting, the percentage was 26 %-70 %, on day 2 the number was 0 %-9 % and on day 3 it was 0 %-1 %. No eggs developed on day 4 and thereafter. Coprological examinations were negative after 4-7 days the treatment was starting.
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