Hepatitis C viruses (HCV) present in 110 Italian patients were characterized by genotype-specific PCRs. Among the 65 cases of community-acquired hepatitis, HCV genotype II was dominant (60%), followed by genotypes IV (15%), III (11%), and I (3%). Among the 45 hemophilia-associated cases, the distribution of the four HCV genotypes was markedly different: genotype I was the most prevalent (61%), followed by genotypes II (25%), III (4%), and IV (2%). Double infections were observed in eight patients. Two HCV remained unclassified. For the 45 community-acquired cases from which a liver biopsy was available, genotype II was associated with more severe liver damage than the other types.
|Autori:||PISTELLO M; MAGGI F; VATTERONI L; CECCONI N; PANICUCCI F; BRESCI GP; GAMBARDELLA L; TADDEI M; BIONDA A; TUONI M; BENDINELLI M|
|Titolo:||PREVALENCE OF HEPATITIS-C VIRUS GENOTYPES IN ITALY|
|Anno del prodotto:||1994|
|Appare nelle tipologie:||1.1 Articolo in rivista|