The invention relates to compounds of general formula (I) and pharmaceutically acceptable salts thereof: (I) wherein Ri is selected from an SCN- group or is an RCONH- group; in particular, where Ri = RCONH, R is selected from an aromatic benzene ring substituted with an SCN- group in the ortho, meta or para position, according to the following formula: SCN- or R is a C1 -C4 alkyl chain, substituted with an SCN- group; n can be equal to 0 or else 1. The invention also relates to the use of such compounds for the treatment of osteoporosis and in general of bone pathologies characterised by a progressive loss of bone mass, for example rheumatoid arthritis, hyperparathyroidism or bone tumour metastases
NEW MOLECULES FOR BONE TISSUE REGENERATION
CALDERONE, VINCENZO;RAPPOSELLI, SIMONA
2014-01-01
Abstract
The invention relates to compounds of general formula (I) and pharmaceutically acceptable salts thereof: (I) wherein Ri is selected from an SCN- group or is an RCONH- group; in particular, where Ri = RCONH, R is selected from an aromatic benzene ring substituted with an SCN- group in the ortho, meta or para position, according to the following formula: SCN- or R is a C1 -C4 alkyl chain, substituted with an SCN- group; n can be equal to 0 or else 1. The invention also relates to the use of such compounds for the treatment of osteoporosis and in general of bone pathologies characterised by a progressive loss of bone mass, for example rheumatoid arthritis, hyperparathyroidism or bone tumour metastases| File | Dimensione | Formato | |
|---|---|---|---|
|
WO2016071863A1(1).pdf
accesso aperto
Tipologia:
Versione finale editoriale
Licenza:
Creative commons
Dimensione
1.29 MB
Formato
Adobe PDF
|
1.29 MB | Adobe PDF | Visualizza/Apri |
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
