Connexins (Cxs) are a family of membrane-spanning proteins known to form membrane channels mediating cell-cell communication. So far, the expression of seven isoform have been found in cardiac myocytes. Cx26 has been described in a number of tissues but not yet in the heart. In the present study we demonstrate for the first time the expression of Cx26 in human, pig, rat and mouse cardiomyicytes . Interestingly C26 was found as scattered throughout cell cytoplasm but not at level of the intercalated disks where the other cardiac Cxs are mainly located.
Connexin 26 expression in mammalian cardiomyocytes
BIANCHI, FRANCESCOPrimo
;SABBATINI, ANTONIETTA RAFFAELLA MARIA;MOSCATO, STEFANIAPenultimo
;MATTII, LETIZIA
Ultimo
2016-01-01
Abstract
Connexins (Cxs) are a family of membrane-spanning proteins known to form membrane channels mediating cell-cell communication. So far, the expression of seven isoform have been found in cardiac myocytes. Cx26 has been described in a number of tissues but not yet in the heart. In the present study we demonstrate for the first time the expression of Cx26 in human, pig, rat and mouse cardiomyicytes . Interestingly C26 was found as scattered throughout cell cytoplasm but not at level of the intercalated disks where the other cardiac Cxs are mainly located.File in questo prodotto:
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