IMPORTANCE Graves orbitopathy (GO) responds to immunosuppressive treatments when clinically active but poorly when inactive. In other autoimmune diseases, response has been ascribed to a reduction in lymphocytes infiltrating the target organ. It is not known whether active vs inactive GO differs in this regard, which would help in understanding the link between GO immunologic features and clinical behavior.
Association of T and B Cells Infiltrating Orbital Tissues With Clinical Features of Graves Orbitopathy
Torregrossa L;Piaggi P;Nardi M;Latrofa F;Basolo F;Marino M
2018-01-01
Abstract
IMPORTANCE Graves orbitopathy (GO) responds to immunosuppressive treatments when clinically active but poorly when inactive. In other autoimmune diseases, response has been ascribed to a reduction in lymphocytes infiltrating the target organ. It is not known whether active vs inactive GO differs in this regard, which would help in understanding the link between GO immunologic features and clinical behavior.File in questo prodotto:
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