Fabrication of fluidic reactors by a customized 3D printing process

Microfluidic systems demonstrated to improve the analysis of biological and chemical processes by providing a more controlled fluid-handling environment. Typically, microfluidic systems are created in monolithic form by means of microfabrication techniques that constrain designers to work in a two-dimensional space. In this regard, Additive Manufacturing (AM) is a powerful set of technologies that can deal with the complexity of 3D structures producing flow paths with sections differing in size and direction. In this work, the use of a commercial laser-based stereolithography 3D printer has been firstly explored to fabricate transparent channels for flow reactors. A custom 3D printer, based on Digital Light Processing Stereolithography (DLP-SLA), has then been developed with the aim at gaining flexibility and overcoming typical limitations raised from standard commercial solutions. The effectiveness of the developed DLP-SLA 3D printer has been experienced by printing transparent fluidic devices with embedded channels with a specifically designed three-step printing process.