Twenty-seven new pregnane glycosides were isolated from the whole plant of Caralluma dalzielii, and their structures elucidated from extensive 2D NMR anal. as well as ESI-MS expts. All isolated compds. were tested for their antiproliferative activity on J774.A1, HEK-293, and WEHI-164 cell lines. Moderate to high potency of cytotoxicities were found in almost all tested compds., confirming the significant cytotoxic activity of pregnane glycosides.
New pregnane glycosides from Caralluma dalzielii
DE LEO, MARINELLA;MORELLI, IVANO;BRACA, ALESSANDRA
2005-01-01
Abstract
Twenty-seven new pregnane glycosides were isolated from the whole plant of Caralluma dalzielii, and their structures elucidated from extensive 2D NMR anal. as well as ESI-MS expts. All isolated compds. were tested for their antiproliferative activity on J774.A1, HEK-293, and WEHI-164 cell lines. Moderate to high potency of cytotoxicities were found in almost all tested compds., confirming the significant cytotoxic activity of pregnane glycosides.File in questo prodotto:
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