In this chapter, the role of ion pairing in the mechanism of the reactions promoted by gold(i) catalysts L-Au-X is elucidated by means of both experimental findings and theoretical calculations. The synergy of the approach allowed the full elucidation of the role of the counterion X - . The catalytic performance in the alkoxylation and hydration of alkynes promoted by gold(i) is influenced by the coordinating ability and basicity (proton affinity) of the counterion, the anion/cation relative orientation and the appropriate matching of X - and L. Finally, how the nature of the anion plays a fundamental role in solvent-, silver- A nd acid-free gold(i)-catalysed hydration of alkynes is highlighted.
CHAPTER 26: Role of ion pairing in the mechanisms of Au(i)-catalysed reactions: Theory and experiment
Ciancaleoni G.;
2019-01-01
Abstract
In this chapter, the role of ion pairing in the mechanism of the reactions promoted by gold(i) catalysts L-Au-X is elucidated by means of both experimental findings and theoretical calculations. The synergy of the approach allowed the full elucidation of the role of the counterion X - . The catalytic performance in the alkoxylation and hydration of alkynes promoted by gold(i) is influenced by the coordinating ability and basicity (proton affinity) of the counterion, the anion/cation relative orientation and the appropriate matching of X - and L. Finally, how the nature of the anion plays a fundamental role in solvent-, silver- A nd acid-free gold(i)-catalysed hydration of alkynes is highlighted.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
