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Cytotoxic auranofin analogues bearing phosphine, arsine and stibine ligands: A study on the possible role of the ligand on the biological activity 1-gen-2023 Giorgi, Ester; Mannelli, Michele; Gamberi, Tania; Durante, Maria; Gabbiani, Chiara; Cirri, Damiano; Pratesi, Alessandro
An overview of recent advancements in anticancer Pt(IV) prodrugs: New smart drug combinations, activation and delivery strategies 1-gen-2023 Marotta, Carlo; Giorgi, Ester; Binacchi, Francesca; Cirri, Damiano; Gabbiani, Chiara; Pratesi, Alessandro
Synthesis, Characterization and Photoactivation Studies on the Novel Pt(IV)-Based [Pt(OCOCH3)3(phterpy)] Complex 1-gen-2023 Canil, Giovanni; Gurruchaga-Pereda, Juan; Braccini, Simona; Marchetti, Lorella; Funaioli, Tiziana; Marchetti, Fabio; Pratesi, Alessandro; Salassa, Luca; Gabbiani, Chiara
Chemical Modification of Auranofin Yields a New Family of Anticancer Drug Candidates: The Gold(I) Phosphite Analogues 1-gen-2023 Cirri, Damiano; Geri, Andrea; Massai, Lara; Mannelli, Michele; Gamberi, Tania; Magherini, Francesca; Becatti, Matteo; Gabbiani, Chiara; Pratesi, Alessandro; Messori, Luigi
Highlights of New Strategies to Increase the Efficacy of Transition Metal Complexes for Cancer Treatments 1-gen-2023 Giorgi, Ester; Binacchi, Francesca; Marotta, Carlo; Cirri, Damiano; Gabbiani, Chiara; Pratesi, Alessandro
Synthesis, chemical characterization, and biological evaluation of a novel auranofin derivative as an anticancer agent 1-gen-2022 Cirri, Damiano; Massai, Lara; Giacomelli, Chiara; Trincavelli, Maria Letizia; Guerri, Annalisa; Gabbiani, Chiara; Messori, Luigi; Pratesi, Alessandro
A focus on the biological targets for coinage metal-NHCs as potential anticancer complexes 1-gen-2021 Guarra, F.; Pratesi, A.; Gabbiani, C.; Biver, T.
Thermodynamic Evaluation of the Interactions between Anticancer Pt(II) Complexes and Model Proteins 1-gen-2021 Pelosi, Chiara; Saitta, Francesca; Zerino, Caterina; Canil, Giovanni; Biver, Tarita; Pratesi, Alessandro; Duce, Celia; Fessas, Dimitrios; Gabbiani, Chiara; Tiné, Maria Rosaria
Protein metalation by two structurally related gold(I) carbene complexes: An ESI MS study 1-gen-2021 Zoppi, C.; Massai, L.; Cirri, D.; Gabbiani, C.; Pratesi, A.; Messori, L.
On the Different Mode of Action of Au(I)/Ag(I)-NHC Bis-Anthracenyl Complexes Towards Selected Target Biomolecules 1-gen-2020 Binacchi, F.; Guarra, F.; Cirri, D.; Marzo, T.; Pratesi, A.; Messori, L.; Gabbiani, C.; Biver, T.
Cytotoxic Ag(I) and Au(I) NHC-carbenes bind DNA and show TrxR inhibition 1-gen-2020 Guarra, F.; Busto, N.; Guerri, A.; Marchetti, L.; Marzo, T.; Garcia, B.; Biver, T.; Gabbiani, C.
124I Radiolabeling of a AuIII-NHC Complex for In Vivo Biodistribution Studies 1-gen-2020 Guarra, F.; Terenzi, A.; Pirker, C.; Passannante, R.; Baier, D.; Zangrando, E.; Gomez-Vallejo, V.; Biver, T.; Gabbiani, C.; Berger, W.; Llop, J.; Salassa, L.
Mechanistic Insights Into the Anticancer Properties of the Auranofin Analog Au(PEt3)I: A Theoretical and Experimental Study 1-gen-2020 Tolbatov, I.; Cirri, D.; Marchetti, L.; Marrone, A.; Coletti, C.; Re, N.; La Mendola, D.; Messori, L.; Marzo, T.; Gabbiani, C.; Pratesi, A.
Reactions of cisplatin and cis-[PtI2(NH3)2] with molecular models of relevant protein sidechains: A comparative analysis 1-gen-2020 Tolbatov, Iogann; Marzo, Tiziano; Cirri, Damiano; Gabbiani, Chiara; Coletti, Cecilia; Marrone, Alessandro; Paciotti, Roberto; Messori, Luigi; Re, Nazzareno
Photocytotoxic Pt(iv) complexes as prospective anticancer agents 1-gen-2019 Canil, Giovanni; Braccini, Simona; Marzo, Tiziano; Marchetti, Lorella; Pratesi, Alessandro; Biver, Tarita; Funaioli, Tiziana; Chiellini, Federica; Hoeschele, James D; Gabbiani, Chiara
Interplay between Gold(I)-Ligand Bond Components and Hydrogen Bonding: A Combined Experimental/Computational Study 1-gen-2019 Marrazzini, G.; Gabbiani, C.; Ciancaleoni, G.
Interaction of gold N-heterocyclic carbenes with nucleic acids 1-gen-2018 Biver, T.; Gabbiani, C.; Pescitelli, G.; Marzo, T.; Bazzicalupi, C.; Gratteri, P.; Messori, L.; Guarra, F.
Synthesis, characterization and DNA interactions of [Pt3(TPymT)Cl3], the trinuclear platinum(II) complex of the TPymT ligand 1-gen-2018 Marzo, Tiziano; Cirri, Damiano; Ciofi, Lorenzo; Gabbiani, Chiara; Feis, Alessandro; Di Pasquale, Nancy; Stefanini, Matteo; Biver, Tarita; Messori, Luigi
Antiproliferative effects of two gold(I)-N-heterocyclic carbene complexes in A2780 human ovarian cancer cells: A comparative proteomic study 1-gen-2018 Magherini, Francesca; Fiaschi, Tania; Valocchia, Elisa; Becatti, Matteo; Pratesi, Alessandro; Marzo, Tiziano; Massai, Lara; Gabbiani, Chiara; Landini, Ida; Nobili, Stefania; Mini, Enrico; Messori, Luigi; Modesti, Alessandra; Gamberi, Tania
Interaction of a Gold(I) Dicarbene Anticancer Drug with Human Telomeric DNA G-Quadruplex: Solution and Computationally Aided X-ray Diffraction Analysis 1-gen-2018 Guarra, Federica; Marzo, Tiziano; Ferraroni, Marta; Papi, Francesco; Bazzicalupi, Carla; Gratteri, Paola; Pescitelli, Gennaro; Messori, Luigi; Biver, Tarita; Gabbiani, Chiara
Chlorido and bromido oxaliplatin analogues as potential agents for CRC treatment: Solution behavior, protein binding and cytotoxicity evaluation 1-gen-2018 Marzo, Tiziano; Pratesi, Alessandro; Cirri, Damiano; Pillozzi, Serena; Petroni, Giulia; Guerri, Annalisa; Arcangeli, Annarosa; Messori, Luigi; Gabbiani, Chiara
Cell and Cell-Free Mechanistic Studies on Two Gold(III) Complexes with Proven Antitumor Properties 1-gen-2017 Nardon, Chiara; Boscutti, Giulia; Gabbiani, Chiara; Massai, Lara; Pettenuzzo, Nicolò; Fassina, Ambrogio; Messori, Luigi; Fregona, Dolores
Ruthenium arene complexes with triphenylphosphane ligands: Cytotoxicity towards pancreatic cancer cells, interaction with model proteins, and effect of ethacrynic acid substitution 1-gen-2017 Biancalana, Lorenzo; Pratesi, Alessandro; Chiellini, Federica; Zacchini, Stefano; Funaioli, Tiziana; Gabbiani, Chiara; Marchetti, Fabio
Mass spectrometry and metallomics: A general protocol to assess stability of metallodrug-protein adducts in bottom-up MS experiments 1-gen-2017 Michelucci, E.; Pieraccini, G.; Moneti, G.; Gabbiani, C.; Pratesi, A.; Messori, L.
Auranofin, Et3PAuCl, and Et3PAuI Are Highly Cytotoxic on Colorectal Cancer Cells: A Chemical and Biological Study 1-gen-2017 Marzo, Tiziano; Cirri, Damiano; Gabbiani, Chiara; Gamberi, Tania; Magherini, Francesca; Pratesi, Alessandro; Guerri, Annalisa; Biver, Tarita; Binacchi, Francesca; Stefanini, Matteo; Arcangeli, Annarosa; Messori, Luigi
PtI2(DACH), the Iodido Analogue of Oxaliplatin as a Candidate for Colorectal Cancer Treatment: Chemical and Biological Features 1-gen-2017 Cirri, Damiano; Pillozzi, Serena; Gabbiani, Chiara; Tricomi, Jacopo; Bartoli, Gianluca; Stefanini, Matteo; Michelucci, Elena; Arcangeli, Annarosa; Messori, Luigi; Marzo, Tiziano
ESI–MS studies of the reactions of novel platinum(II) complexes containing O,O′-chelated acetylacetonate and sulfur ligands with selected model proteins 1-gen-2017 Marzo, Tiziano; De Pascali, Sandra A.; Gabbiani, Chiara; Fanizzi, Francesco P.; Messori, Luigi; Pratesi, Alessandro
Gold compounds as cysteine protease inhibitors: perspectives for pharmaceutical application as antiparasitic agents 1-gen-2017 Massai, L; Messori, L; Micale, N; Schirmeister, T; Maes, L; Fregona, D; Cinellu, Ma; Gabbiani, Chiara
Anticancer gold N-Heterocyclic carbene complexes: a comparative in vitro and ex vivo study 1-gen-2017 Estrada-Ortiz, N.; Guarra, F.; de Graaf, I. A. M.; Marchetti, L.; de Jager, M. H.; Groothuis, G. M. M.; Gabbiani, C.; Casini, A.
Triethylphosphine gold iodide (I), the iodido analogue of Auranofin: comparative studies of a potential antineoplastic agent 1-gen-2016 Marzo, Tiziano; Cirri, D.; Gabbiani, Chiara; Guerri, A.; Biver, Tarita; Binacchi, F.; Stefanini, M.; Arcangeli, A.; Messori, L.
Synthesis and Antiproliferative Activity of New Ruthenium Complexes with Ethacrynic Acid-Modified Ligands 1-gen-2016 Agonigi, Gabriele; Biancalana, Lorenzo; Chiellini, Federica; Dyson, Paul J.; Funaioli, Tiziana; Gabbiani, Chiara; Marchetti, Fabio; Pampaloni, Guido; Riedel, T.; Zacchini, S.
Arene Ruthenium Complexes with Ethacrynic Acid-Modified Ligands: Synthesis, Characterization and Antiproliferative Activity 1-gen-2016 Agonigi, Gabriele; Biancalana, Lorenzo; Chiellini, Federica; Dyson, Paul J.; Funaioli, Tiziana; Gabbiani, Chiara; Marchetti, Fabio; Pampaloni, Guido; Riedel, T.; Zacchini, S.
Cisplatin and its dibromido analogue: a comparison of chemical and biological profiles 1-gen-2016 Marzo, Tiziano; Bartoli, Gianluca; Gabbiani, Chiara; Pescitelli, Gennaro; Severi, Mirko; Pillozzi, Serena; Michelucci, Elena; Fiorini, Benedetta; Arcangeli, Annarosa; Quiroga, Adoracion G.; Messori, Luigi
First Crystal Structure for a Gold Carbene-Protein Adduct 1-gen-2016 Ferraro, G.; Gabbiani, Chiara; Merlino, A.
Organogold(III) compounds as experimental anticancer agents: chemical and biological profiles 1-gen-2016 Massai, L.; Cirri, D.; Michelucci, E.; Bartoli, G.; Guerri, A.; Cinellu, M. A.; Cocco, F.; Gabbiani, Chiara; Messori, L.
Potent in vitro antiproliferative properties for a triplatinum cluster toward triple negative breast cancer cells 1-gen-2016 Gabbiani, Chiara; Pratesi, Alessandro; Marchetti, Lorella; Casini, Angela; Leoni, Piero; Pillozzi, Serena; Crociani, Olivia; Bartoli, Gianluca; Messori, Luigi
cis-Pt I2(NH3)2: a reappraisal 1-gen-2015 Marzo, Tiziano; Pillozzi, Serena; Hrabina, Ondrej; Kasparkova, Jana; Brabec, Viktor; Arcangeli, Annarosa; Bartoli, Gianluca; Severi, Mirko; Lunghi, Alessandro; Totti, Federico; Gabbiani, Chiara; Quiroga, Adoracion G; Messori, Luigi
Proteomic analysis of the cytotoxic effects induced by the organogold(iii) complex Aubipyc in cisplatin-resistant A2780 ovarian cancer cells: further evidence for the glycolytic pathway implication 1-gen-2015 Gamberi, Tania; Magherini, Francesca; Fiaschi, Tania; Landini, Ida; Massai, Lara; Valocchia, Elisa; Bianchi, Laura; Bini, Luca; Gabbiani, Chiara; Nobili, Stefania; Mini, Enrico; Messori, Luigi; Modesti, Alessandra
Interactions of the organogold(III) compound Aubipyc with the copper chaperone Atox1: A joint mass spectrometry and circular dichroism investigation 1-gen-2015 Marzo, Tiziano; Scaletti, Federica; Michelucci, Elena; Gabbiani, Chiara; Pescitelli, Gennaro; Messori, Luigi; Massai, Lara
Mechanistic studies on cytotoxic gold compounds 1-gen-2014 Gabbiani, Chiara; Luigi, Messori; Lara, Massai; Federica, Scaletti; Marzo, Tiziano
Proteomic analysis of A2780/S ovarian cancer cell response to the cytotoxic organogold(III) compound Aubipyc 1-gen-2014 Gamberi, T.; Massai, L.; Magherini, F.; Landini, I.; Fiaschi, T.; Scaletti, F.; Gabbiani, Chiara; Bianchi, L.; Bini, L.; Nobili, S.; Perrone, G.; Mini, E.; Messori, L.; Modesti, A.
Novel platinum(II) compounds with O,S bidentate ligands: Synthesis, characterization, antiproliferative properties and biomolecular interactions 1-gen-2014 Mügge, C.; Liu, R.; Görls, H.; Gabbiani, Chiara; Michelucci, E.; Rüdiger, N.; Clement, J. H.; Messori, L.; Weigand, W.
Chemistry and Biology of Two Novel Gold(I) Carbene Complexes as Prospective Anticancer Agents 1-gen-2014 Luigi, Messori; Marchetti, Lorella; Lara, Massai; Federica, Scaletti; Annalisa, Guerri; Ida, Landini; Stefania, Nobili; Gabriele, Perrone; Enrico, Mini; Leoni, Piero; Pasquali, Marco; Gabbiani, Chiara
Selected cytotoxic gold compounds cause significant inhibition of 20S proteasome catalytic activities 1-gen-2014 Micale, N.; Schirmeister, T.; Ettari, R.; Cinellu, M. A.; Maiore, L.; Serratrice, M.; Gabbiani, Chiara; Massai, L.; Messori, L.
Insights on the mechanism of thioredoxin reductase inhibition by Gold N-heterocyclic carbene compounds using the synthetic linear Selenocysteine containing C-terminal peptide hTrxR(488-499): An ESI-MS investigation 1-gen-2014 Pratesi, A.; Gabbiani, Chiara; Michelucci, E.; Ginanneschi, M.; Papini, A. M.; Rubbiani, R.; Ott, I.; Messori, L.
Nitrate as a probe of cytochrome c surface: Crystallographic identification of crucial "hot spots" for protein-protein recognition 1-gen-2014 De, March; M., Demitri; De, Zorzi; R., Casini; Gabbiani, Chiara; C., Guerri; A., Messori; L., Geremia
New insights into the molecular mechanisms of selected anticancer metal compounds through bioinformatic analysis of proteomic data 1-gen-2013 Gamberi, T.; Magherini, F.; Bini, L.; Messori, L.; Gabbiani, Chiara; Pietrovito, L.; Modesti, P. A.; Modesti, A.
Peculiar features in the crystal structure of the adduct formed between cis-PtI2(NH3)2 and hen egg white lysozyme. 1-gen-2013 Messori, L.; Marzo, Tiziano; Gabbiani, Chiara; Valdes, A. A.; Quiroga, A. G.; Merlino, A.
Metal-based compounds as prospective antileishmanial agents: Inhibition of Trypanothione reductase by selected gold complexes 1-gen-2013 Colotti, G.; Ilari, A.; Fiorillo, A.; Baiocco, P.; Cinellu, M. A.; Maiore, L.; Scaletti, F.; Gabbiani, Chiara; Messori, L.
The molecular mechanisms of antimetastatic ruthenium compounds explored through DIGE proteomics 1-gen-2013 Guidi, F; Modesti, A; Landini, I; Nobili, S; Mini, E; Bini, L; Puglia, M; Casini, A; Dyson, Pj; Gabbiani, Chiara; Messori, L.
Promising in Vitro anti-alzheimer properties for a ruthenium(III) complex 1-gen-2013 Messori, L.; Camarri, M.; Ferraro, T.; Gabbiani, Chiara; Franceschini, D.
The mode of action of anticancer gold-based drugs: A structural perspective 1-gen-2013 Messori, L.; Scaletti, F.; Massai, L.; Cinellu, M. A.; Gabbiani, Chiara; Vergara, A.; Merlino, A.
Butyltin(IV) benzoates: inhibition of thioredoxin reductase, tumor cell growth inhibition, and interactions with proteins 1-gen-2013 Navakoski de Oliveira, K.; Andermark, V.; von Grafenstein, S.; Onambele, L. A.; Dahl, G.; Rubbiani, R.; Wolber, G.; Gabbiani, Chiara; Messori, L.; Prokop, A.; Ott, I.
Gold(III) complexes with 2-substituted pyridines as experimental anticancer agents: Solution behavior, reactions with model proteins, antiproliferative properties 1-gen-2012 Maiore, L; Cinellu, Ma; Nobili, S; Landini, I; Mini, E; Gabbiani, Chiara; Messori, L.
Metal compounds as inhibitors of B-amyloid aggregation. Perspectives for an innovative metallotherapeutics on Alzheimer’s disease 1-gen-2012 D., Valensin; Gabbiani, Chiara; L., Messori
Proteomic analysis of ovarian cancer cell responses to cytotoxic gold compounds 1-gen-2012 Guidi, F; Landini, I; Puglia, M; Magherini, F; Gabbiani, Chiara; Cinellu, Ma; Nobili, S; Fiaschi, T; Bini, L; Mini, E; Messori, L; Modesti, A.
Synthesis, Structural Characterization, Solution Behavior, and in Vitro Antiproliferative Properties of a Series of Gold Complexes with 2-(2'-Pyridyl)benzimidazole as Ligand: Comparisons of Gold(III) versus Gold(I) and Mononuclear versus Binuclear Derivatives 1-gen-2012 M., Serratrice; M. A., Cinellu; L., Maiore; M., Pilo; A., Zucca; Gabbiani, Chiara; A., Guerri; I., Landini; S., Nobili; E., Mini; L., Messori
Reactivity and Biological Properties of a Series of Cytotoxic PtI(2)(amine)(2) Complexes, Either cis or trans Configured 1-gen-2012 Messori, L; Cubo, L; Gabbiani, Chiara; Alvarez Valdés, A; Michelucci, E; Pieraccini, G; Ríos Luci, C; León, Lg; Padrón, Jm; Navarro Ranninger, C; Casini, A; Quiroga, Ag
Medicinal gold compounds form tight adducts with the copper chaperone Atox-1: biological and pharmacological implications. 1-gen-2012 Gabbiani, Chiara; Scaletti, F; Massai, L; Michelucci, E; Cinellu, Ma; Messori, L.
Chemistry and biology of three representative gold(III) compounds as prospective anticancer agents 1-gen-2012 Gabbiani, Chiara; M. A., Cinellu; L., Maiore; L., Massai; F., Scaletti; L., Messori
Protein metalation by metal-based drugs: reactions of cytotoxic gold compounds with cytochrome c and lysozyme 1-gen-2012 Gabbiani, Chiara; L., Massai; F., Scaletti; E., Michelucci; L., Maiore; M. A., Cinellu; L., Messori
2D-DIGE analysis of ovarian cancer cell responses to cytotoxic gold compounds 1-gen-2012 Guidi, F; Puglia, M; Gabbiani, Chiara; Landini, I; Gamberi, T; Fregona, D; Cinellu, Ma; Nobili, S; Mini, E; Bini, L; Modesti, Pa; Modesti, A; Messori, L.
Mechanistic studies on two dinuclear organogold(III) compounds showing appreciable antiproliferative properties and a high redox stability 1-gen-2011 Gabbiani, Chiara; Casini, A; Kelter, G; Cocco, F; Cinellu, Ma; Fiebig, Hh; Messori, L.
Hypericins and thioredoxin reductase: Biochemical and docking studies disclose the molecular basis for effective inhibition by naphthodianthrones 1-gen-2011 Sorrentino, F; Karioti, A; Gratteri, P; Rigobello, Mp; Scutari, G; Messori, L; Bindoli, A; Chioccioli, M; Gabbiani, Chiara; Bergonzi, Mc; Bilia, Ar
Aluminum, copper, iron and zinc differentially alter amyloid-Abeta(1-42) aggregation and toxicity 1-gen-2011 Bolognin, S; Messori, L; Drago, D; Gabbiani, Chiara; Cendron, L; Zatta, P.
Protein Targets for Anticancer Gold Compounds: Mechanistic Inferences 1-gen-2011 Gabbiani, Chiara; L., Messori
Reactions of metallodrugs with proteins: selective binding of phosphane-based platinum(II) dichlorides to horse heart cytochrome c probed by ESI MS coupled to enzymatic cleavage. 1-gen-2011 Mügge, C; Micheucci, E; Boscaro, F; Gabbiani, Chiara; Messori, L; Weigand, W.
Structure, solution chemistry, antiproliferative actions and protein binding properties of non-conventional platinum(II) compounds with sulfur and phosphorus donors. 1-gen-2011 Mügge, C; Rothenburger, C; Beyer, A; Görls, H; Gabbiani, Chiara; Casini, A; Michelucci, E; Landini, I; Nobili, S; Mini, E; Messori, L; Weigand, W.
Recent progress in the application of analytical techniques to anticancer metallodrug proteomics 1-gen-2011 Timerbaev, Ar; Pawlak, K; Gabbiani, Chiara; Messori, L.
Selected gold compounds cause pronounced inhibition of Falcipain 2 and effectively block P. falciparum growth in vitro 1-gen-2011 Micale, N; Cinellu, Ma; Maiore, L; Sannella, Ar; Severini, C; Schirmeister, T; Gabbiani, Chiara; Messori, L.
Thioredoxin reductase, an emerging target for anticancer metallodrugs. Enzyme inhibition by cytotoxic gold(III) compounds studied with combined mass spectrometry and biochemical assays 1-gen-2011 Gabbiani, Chiara; Mastrobuoni, G; Sorrentino, F; Dani, B; Rigobello, Mp; Bindoli, A; Cinellu, Ma; Pieraccini, G; Messori, L; Casini, A.
X-ray absorption spectroscopy studies of the adducts formed between cytotoxic gold compounds and two major serum proteins 1-gen-2011 Messori, L; Balerna, A; Ascone, I; Castellano, C; Gabbiani, Chiara; Casini, A; Marchioni, C; Jaouen, G; Congiu Castellano, A.
Structural and solution chemistry, protein binding and antiproliferative profiles of gold(I)/(III) complexes bearing the saccharinato ligand 1-gen-2011 Maiore, L; Cinellu, Ma; Michelucci, E; Moneti, G; Nobili, S; Landini, I; Mini, E; Guerri, A; Gabbiani, Chiara; Messori, L.
Exploring the Reactions of beta-Amyloid (A beta) Peptide 1-28 with Al(III) and Fe(III) Ions 1-gen-2011 Valensin, D; Migliorini, C; Valensin, G; Gaggelli, E; La Penna, G; Kozlowski, H; Gabbiani, Chiara; Messori, L.
Dinuclear Gold(III) Complexes as Potential Anticancer Agents: Structure, Reactivity and Biological Profile of a Series of Gold(III) Oxo-Bridged Derivatives 1-gen-2010 Gabbiani, Chiara; A., Guerri; M. A., Cinellu; L., Messori
Trans-cis-cis-[RuCl(2)(DMSO)(2)(2-amino-5-methyl-thiazole)(2)], (PMRu52), a novel ruthenium(II) compound acting as a strong inhibitor of cathepsin B 1-gen-2010 Mura, P; Camalli, M; Casini, A; Gabbiani, Chiara; Messori, L.
Exploring the biochemical mechanisms of cytotoxic gold compounds: a proteomic study 1-gen-2010 Magherini, F; Modesti, A; Bini, L; Puglia, M; Landini, I; Nobili, S; Mini, E; Cinellu, Ma; Gabbiani, Chiara; Messori, L.
Trace Copper(II) or Zinc(II) Ions Drastically Modify the Aggregation Behavior of Amyloid-beta(1-42): An AFM Study 1-gen-2010 Innocenti, M; Salvietti, E; Guidotti, M; Casini, A; Bellandi, S; Foresti, Ml; Gabbiani, Chiara; Pozzi, A; Zatta, P; Messori, L.
[Au2(phen2Me)2(µ-O)2](PF6)2, a Novel Dinuclear Gold(III) Complex Showing Excellent Antiproliferative Properties 1-gen-2010 Cinellu, Ma; Maiore, L; Manassero, M; Casini, A; Arca, M; Fiebig, Hh; Kelter, G; Michelucci, E; Pieraccini, G; Gabbiani, Chiara; Messori, L.
Proteomic and Metallomic Strategies for Understanding the Mode of Action of Anticancer Metallodrugs 1-gen-2010 Gabbiani, Chiara; Magherini, F; Modesti, A; Messori, L.
Reactions of medicinally relevant gold compounds with the C-terminal motif of thioredoxin reductase elucidated by MS analysis 1-gen-2010 Pratesi, A; Gabbiani, Chiara; Ginanneschi, M; Messori, L.
Gold compounds as anticancer agents: chemistry, cellular pharmacology, and preclinical studies. 1-gen-2010 Nobili, S; Mini, E; Landini, I; Gabbiani, Chiara; Casini, A; Messori, L.
Metal-based drugs for malaria, trypanosomiasis and leishmaniasis: recent achievements and perspectives 1-gen-2010 Navarro, M; Gabbiani, Chiara; Messori, L; Gambino, D.
New platinum-oxicam complexes as anti-cancer drugs. Synthesis, characterization, release studies from smart hydrogels, evaluation of reactivity with selected proteins and cytotoxic activity in vitro 1-gen-2010 Tamasi, G; Casolaro, M; Magnani, A; Sega, A; Chiasserini, L; Messori, L; Gabbiani, Chiara; Valiahdi, Sm; Jakupec, Ma; Keppler, Bk; Hursthouse, Mb; Cini, R.
Cytotoxic Profile and Peculiar Reactivity with Biomolecules of a Novel "Rule-Breaker" Iodidoplatinum(II) Complex 1-gen-2010 Messori, L; Casini, A; Gabbiani, Chiara; Michelucci, E; Cubo, L; Rios Luci, C; Padron, Jm; Navarro Ranninger, C; Quiroga, Ag
The X-ray Structure of the Adduct between NAMI-A and Carbonic Anhydrase Provides Insights into the Reactivity of this Metallodrug with Proteins 1-gen-2010 Casini, A; Temperini, C; Gabbiani, Chiara; Supuran, Ct; Messori, L.
fac-{Ru(CO)(3)}(2+) selectively targets the histidine residues of the beta-amyloid peptide 1-28. Implications for new Alzheimer's disease treatments based on ruthenium complexes. 1-gen-2010 Valensin, D; Anzini, P; Gaggelli, E; Gaggelli, N; Tamasi, G; Cini, R; Gabbiani, Chiara; Michelucci, E; Messori, L; Kozlowski, H; Valensin, G.
Proteins as possible targets for antitumor metal complexes: biophysical studies of their interactions 1-gen-2009 Gabbiani, Chiara
Thioredoxin reductase: A target for gold compounds acting as potential anticancer drugs 1-gen-2009 Bindoli, A; Rigobello, Mp; Scutari, G; Gabbiani, Chiara; Casini, A; Messori, L.
Proanthocyanidin glycosides from the leaves of Quercus ilex L. (Fagaceae) 1-gen-2009 Karioti, A; Bilia, Ar; Gabbiani, Chiara; Messori, L; Skaltsa, H.
Solution Behaviour and Biomolecular Interactions of Two Cytotoxic trans-Platinum(II) Complexes Bearing Aliphatic Amine Ligands 1-gen-2009 Cubo, L; Casini, A; Gabbiani, Chiara; Mastrobuoni, G; Messori, L; Jimenez Barbero, J; Navarro Ranninger, C; Quiroga, Ag
Outstanding plasmodicidal properties within a small panel of metallic compounds: Hints for the development of new metal-based antimalarials 1-gen-2009 Gabbiani, Chiara; Messori, L; Cinellu, Ma; Casini, A; Mura, P; Sannella, Ar; Severini, C; Majori, G; Bilia, Ar; Vincieri, Ff
Exploring metallodrug-protein interactions by mass spectrometry: comparisons between platinum coordination complexes and an organometallic ruthenium compound 1-gen-2009 Casini, A; Gabbiani, Chiara; Michelucci, E; Pieraccini, G; Moneti, G; Dyson, Pj; Messori, L.
Reactivity of an antimetastatic organometallic ruthenium compound with metallothionein-2: relevance to the mechanism of action 1-gen-2009 Casini, A; Karotki, A; Gabbiani, Chiara; Rugi, F; Vasak, M; Messori, L; Dyson, Pj
Chemistry, antiproliferative properties, tumor selectivity, and molecular mechanisms of novel gold(III) compounds for cancer treatment: a systematic study 1-gen-2009 Casini, A; Kelter, G; Gabbiani, Chiara; Cinellu, Ma; Minghetti, G; Fregona, D; Fiebig, Hh; Messori, L.
Clioquinol decreases amyloid-beta burden and reduces working memory impairment in a transgenic mouse model of Alzheimer's disease. 1-gen-2009 C., Grossi; S., Francese; A., Casini; M. C., Rosi; I., Luccarini; A., Fiorentini; Gabbiani, Chiara; L., Messori; G., Moneti; F., Casamenti
Emerging Protein Targets for Anticancer Metallodrugs: Inhibition of Thioredoxin Reductase and Cathepsin B by Antitumor Ruthenium(II)-Arene Compounds 1-gen-2008 A., Casini; Gabbiani, Chiara; F., Sorrentino; M. P., Rigobello; A., Bindoli; T. J., Geldbach; A., Marrone; N., Re; C. G., Hartinger; P. J., Dyson; L., Messori
Structural characterization, solution studies, and DFT calculations on a series of binuclear gold(III) oxo complexes: relationships to their biological properties 1-gen-2008 Gabbiani, Chiara; A., Casini; L., Messori; A., Guerri; M. A., Cinellu; G., Minghetti; M., Corsini; C., Rosani; P., Zanello; M., Arca
The influence of auranofin, a clinically established antiarthritic gold drug, on bone metabolism: analysis of its effects on human multipotent adipose-derived stem cells, taken as a model 1-gen-2008 Chiellini, C; Casini, A; Cochet, O; Gabbiani, Chiara; Ailhaud, G; Dani, C; Messori, L; Amri, Ez
New uses for old drugs. Auranofin, a clinically established antiarthritic metallodrug, exhibits potent antimalarial effects in vitro: Mechanistic and pharmacological implications 1-gen-2008 A. R., Sannella; A., Casini; Gabbiani, Chiara; L., Messori; A. R., Bilia; F. F., Vincieri; G., Majori; C., Severini
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