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Titolo Data di pubblicazione Autore(i) File
Estrogen receptor ligands: a patent review update 1-gen-2013 Paterni, Ilaria; Bertini, Simone; Granchi, Carlotta; Macchia, Marco; Minutolo, Filippo
Dual Targeting of the Warburg Effect with a Glucose-Conjugated Lactate Dehydrogenase Inhibitor 1-gen-2013 Emilia C., Calvaresi; Granchi, Carlotta; Tuccinardi, Tiziano; DI BUSSOLO, Valeria; Robert W., Huigens III; Hyang Yeon, Lee; Rahul, Palchaudhuri; Macchia, Marco; Martinelli, Adriano; Minutolo, Filippo; Paul J., Hergenrother
COMPOUNDS INHIBITING THE ENZYME LACTATE DEHYDROGENASE (LDH), PHARMACEUTICAL COMPOSITIONS AND USES THEREOF 1-gen-2013 Mario, Varasi; Morelli, Matteo; Granchi, Carlotta; Tuccinardi, Tiziano; DI BUSSOLO, Valeria; Macchia, Marco; Martinelli, Adriano; Minutolo, Filippo
Synergistic interaction of novel lactate dehydrogenase inhibitors with gemcitabine against pancreatic cancer cells in hypoxia 1-gen-2014 Mina, Maftouh; Amir, Avan; Rocco, Sciarrillo; Granchi, Carlotta; Leticia G., Leon; Rani, Reshma; Funel, Niccola; Kees, Smid; Richard, Honeywell; Boggi, Ugo; Minutolo, Filippo; Godefridus J., Peters; Elisa, Giovannetti
An update on therapeutic opportunities offered by cancer glycolytic metabolism 1-gen-2014 Granchi, Carlotta; Fancelli, D.; Minutolo, Filippo
Identification and characterization of a new reversible MAGL inhibitor 1-gen-2014 Tuccinardi, Tiziano; Granchi, Carlotta; Rizzolio, F; Caligiuri, I; Battistello, V; Toffoli, G; Minutolo, Filippo; Macchia, Marco; Martinelli, Adriano
Estrogen Receptors Alpha (ERα) and Beta (ERβ): Subtype-Selective Ligands and Clinical Potential 1-gen-2014 Paterni, Ilaria; Granchi, Carlotta; John A., Katzenellenbogen; Minutolo, Filippo
Synergistic interaction of novel lactate dehydrogenase inhibitors with gemcitabine against pancreatic cancer cells in hypoxia. 1-gen-2014 Maftouh, M; Avan, A; Sciarrillo, R; Granchi, Carlotta; Leon, Lg; Rani, R; Funel, Niccola; Smid, K; Honeywell, R; Boggi, Ugo; Minutolo, F; Peters, Gj; Giovannetti, Elisa
Identification of LDH-A as a therapeutic target for cancer cell killing via (i) p53/NAD(H)-dependent and (ii) p53-independent pathways 1-gen-2014 Simon, Allison; John, Knight; Granchi, Carlotta; Rani, Reshma; Minutolo, Filippo; Jo, Milner; Roger, Phillips
Receptor-based virtual screening evaluation for the identification of estrogen receptor β ligands 1-gen-2015 Tuccinardi, Tiziano; Poli, Giulio; Dell’Agnello, M; Granchi, Carlotta; Minutolo, Filippo; Martinelli, Adriano
Synthesis and biological evaluation of non-glucose glycoconjugated N-hydroyxindole class LDH inhibitors as anticancer agents 1-gen-2015 DI BUSSOLO, Valeria; Emilia, Calvaresi; Granchi, Carlotta; Linda Del, Bino; Ileana, Frau; Maria Chiara Dasso, Lang; Tuccinardi, Tiziano; Macchia, Marco; Martinelli, Adriano; Paul J., Hergenrother; Minutolo, Filippo
Salicylketoximes that target glucose transporter 1 restrict energy supply to lung cancer cells 1-gen-2015 Granchi, Carlotta; Qian, Yanrong; Lee, Hyang Yeon; Paterni, Ilaria; Pasero, Carolina; Iegre, Jessica; Carlson, Kathryn E; Tuccinardi, Tiziano; Chen, Xiaozhuo; Katzenellenbogen, John A; Hergenrother, Paul J; Minutolo, Filippo
Bioactive heterocycles containing endocyclic N-hydroxy groups 1-gen-2015 Rani, Reshma; Granchi, Carlotta
Phenylpropanoids and flavonoids from Phlomis kurdica as inhibitors of human lactate dehydrogenase. 1-gen-2015 Bader, A; Tuccinardi, Tiziano; Granchi, Carlotta; Martinelli, Adriano; Macchia, Marco; Minutolo, Filippo; De Tommasi, N; Braca, Alessandra
Lactate dehydrogenase-A inhibition induces human glioblastoma multiforme stem cell differentiation and death 1-gen-2015 Daniele, Simona; Giacomelli, Chiara; Zappelli, Elisa; Granchi, Carlotta; Trincavelli, MARIA LETIZIA; Minutolo, Filippo; Martini, Claudia
Development and validation of a docking-based virtual screening platform for the identification of new lactate dehydrogenase inhibitors 1-gen-2015 Granchi, Carlotta; Capecchi, Alice; Del Frate, Gianluca; Martinelli, Adriano; Macchia, Marco; Minutolo, Filippo; Tuccinardi, Tiziano
Highly Selective Salicylketoxime-Based Estrogen Receptor β Agonists Display Antiproliferative Activities in a Glioma Model 1-gen-2015 Paterni, Ilaria; Bertini, Simone; Granchi, Carlotta; Tuccinardi, Tiziano; Macchia, Marco; Martinelli, Adriano; Isabella, Caligiuri; Giuseppe, Toffoli; Flavio, Rizzolio; Kathryn E., Carlson; Benita S., Katzenellenbogen; John A., Katzenellenbogen; Minutolo, Filippo
4-Aryliden-2-methyloxazol-5(4H)-one as a new scaffold for selective reversible MAGL inhibitors 1-gen-2016 Granchi, Carlotta; Rizzolio, F; Bordoni, Vittorio; Caligiuri, I; Manera, Clementina; Macchia, Marco; Minutolo, Filippo; Martinelli, Adriano; Giordano, A; Tuccinardi, Tiziano
A Virtual Screening Study for Lactate Dehydrogenase 5 Inhibitors by using a Pharmacophore-Based Approach 1-gen-2016 Tuccinardi, Tiziano; Poli, Giulio; Corchia, Isacco; Granchi, Carlotta; Lapillo, Margherita; Macchia, Marco; Minutolo, Filippo; Ortore, GABRIELLA MARIA PIA; Martinelli, Adriano
Synthesis and biological evalutation of new glycoconjugated LDH inhibitors as anticancer agents 1-gen-2016 D'Andrea, Felicia; DI BUSSOLO, Valeria; Granchi, Carlotta; Lee, Hyang Yeon; Hergenrother, Paul J.; Minutolo, Filippo; Vagelli, Giulia
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