LAPUCCI, ANNALINA Statistiche
LAPUCCI, ANNALINA
DIPARTIMENTO DI FARMACIA
Locking PDK1 in DFG-out conformation through 2-oxo-indole containing molecules: Another tools to fight glioblastoma
2016-01-01 Sestito, Simona; Daniele, Simona; Nesi, Giulia; Zappelli, Elisa; Di Maio, D; Marinelli, L; Digiacomo, Maria; Lapucci, Annalina; Martini, Claudia; Novellino, E; Rapposelli, Simona
Synthesis and In Vivo Imaging of N-(3-[11C]Methoxybenzyl)-2-(3-Methoxyphenyl)ethylaniline as a Potential Targeting Agent for P-glycoprotein
2016-01-01 Petroni, Debora; Bartoli, Antonietta; Rapposelli, Simona; Digiacomo, Maria; Burchielli, Silvia; Nesi, Giulia; Lapucci, Annalina; Pardini, Silvia; Fucci, Sabrina; Macchia, Marco; Salvadori, Piero A.; Menichetti, Luca
Design and synthesis of 2-oxindole based multi-targeted inhibitors of PDK1/Akt signaling pathway for the treatment of glioblastoma multiforme
2015-01-01 Sestito, Simona; Nesi, Giulia; Daniele, Simona; Martelli, Alma; Digiacomo, Maria; Borghini, Alice; Pietra, Daniele; Calderone, Vincenzo; Lapucci, Annalina; Falasca, Marco; Parrella, Paola; Notarangelo, Angelantonio; Breschi, MARIA CRISTINA; Macchia, Marco; Martini, Claudia; Rapposelli, Simona
Synthesis and evaluation of multi-functional NO-donor/insulin-secretagogue derivatives for the treatment of type II diabetes and its cardiovascular complications
2015-01-01 Digiacomo, Maria; Martelli, Alma; Testai, Lara; Lapucci, Annalina; Breschi, MARIA CRISTINA; Calderone, Vincenzo; Rapposelli, Simona
Synthesis and pharmacological evaluation of multifunctional tacrine derivatives against several disease pathways of AD
2015-01-01 Digiacomo, Maria; Chen, Ziwei; Wang, Shengnan; Lapucci, Annalina; Macchia, Marco; Yang, Xiaohong; Chu, Jiaqi; Han, Yifan; Pi, Rongbiao; Rapposelli, Simona
SAR study on arylmethyloxyphenyl scaffold: Looking for a P-gp nanomolar affinity
2014-01-01 Nesi, Giulia; Colabufo, N. A.; Contino, M.; Perrone, M. G.; Digiacomo, Maria; Perrone, R.; Lapucci, Annalina; Macchia, Marco; Rapposelli, Simona
Synthesis and biological evaluation of (Hetero)aryl-methyloxyphenyl derivatives as potent P-glycoprotein modulating agents.
2013-01-01 Nesi, Giulia; Colabufo, N. A.; Contino, M.; Perrone, M. G.; Digiacomo, Maria; Perrone, R.; Lapucci, Annalina; Macchia, Marco; Rapposelli, Simona
Synthesis of Novel 3,5-Disubstituted-2-oxindole Derivatives As Antitumor Agents against Human Nonsmall Cell Lung Cancer
2013-01-01 Nesi, Giulia; Sestito, Simona; Mey, V.; Ricciardi, S.; Falasca, M.; Danesi, Romano; Lapucci, Annalina; Breschi, MARIA CRISTINA; Fogli, Stefano; Rapposelli, Simona
Targeting the upregulated PI3K-PDK1-Akt pathway: a drug discovery approach of treating cancer.
2012-01-01 Nesi, Giulia; Danesi, Romano; Lapucci, Annalina; Ricciardi, S; Sestito, Simona; Rapposelli, Simona
Synthesis and Biological Evaluation of 2'-Oxo-2,3-dihydro-3'H-spiro[chromene-4,5'-[1,3]oxazolidin]3'il]acetic Acid Derivatives as Aldose reductase Inhibitors
2011-01-01 Rapposelli, Simona; DA SETTIMO PASSETTI, Federico; Digiacomo, Maria; LA MOTTA, Concettina; Lapucci, Annalina; Sartini, Stefania; Vanni, M.
Synthesis, molecular docking and binding studies of selective serotonin transporter inhibitors
2011-01-01 Nencetti, Susanna; Mazzoni, MARIA ROSA; Ortore, GABRIELLA MARIA PIA; Lapucci, Annalina; Giuntini, Janette; Orlandini, Elisabetta; Banti, Irene; Nuti, Elisa; Lucacchini, Antonio; Giannaccini, Gino; Rossello, Armando
Therapeutic potential of sulindac hydroxamic acid against human pancreatic and colonic cancer cells
2010-01-01 Fogli, Stefano; Banti, I; Stefanelli, Fabio; Picchianti, L; Digiacomo, Maria; Macchia, Marco; Breschi, MARIA CRISTINA; Lapucci, Annalina
In vitro investigation of sulindac derivatives as potential anticancer agents
2009-01-01 Fogli, Stefano; Banti, I; Digiacomo, Maria; Macchia, Marco; Lapucci, Annalina; Breschi, MARIA CRISTINA
Novel Transthyretin Amyloid Fibril Formation Inhibitors: Synthesis, Biological Evaluation, and X-Ray Structural Analysis
2009-01-01 Palaninathan, S. K.; Mohamedmohaideen, N. N.; Orlandini, Elisabetta; Ortore, GABRIELLA MARIA PIA; Nencetti, Susanna; Lapucci, Annalina; Rossello, Armando; FREUNDLINCH JL, S; Sacchettini, J. C.
Synthesis and in-vitro antitumour activity of new naphthyridine derivatives on human pancreatic cancer cells
2009-01-01 Banti, I; Nencetti, Susanna; Orlandini, Elisabetta; Lapucci, Annalina; Breschi, MARIA CRISTINA; Fogli, Stefano
Allosteric inhibition of (125I) ET-1 binding to ET(A) receptors by aldoxime and hydroxamic acid derivatives
2008-01-01 Ahmed, M; Nencetti, Susanna; Mazzoni, MARIA ROSA; Porchia, F; Antonelli, F; Lapucci, Annalina
Allosteric inhibition of ET-1 binding to ETA receptors by aldoxime derivatives
2008-01-01 Ahmed, Musa; Nencetti, Susanna; Mazzoni, MARIA ROSA; Porchia, Francesca; Antonelli, Federica; Lapucci, Annalina
Inhibition of [125] ET-1 binding to ETA receptors by salicilic acid dimers
2008-01-01 Musa, Ahmed; Nencetti, Susanna; Mazzoni, MARIA ROSA; Francesca, Porchia; Federica, Antonelli; Lapucci, Annalina
Monoaryl-substituted Salicylaldoximes as Ligands for Estrogen Receptor Beta
2008-01-01 Minutolo, Filippo; Bellini, R; Bertini, Simone; Carboni, I; Lapucci, Annalina; Pistolesi, L; Prota, G; Rapposelli, Simona; Solati, F; Tuccinardi, Tiziano; Martinelli, Adriano; Stossi, F; Carlson, K. E.; Katzenellenbogen, B. S.; Katzenellenbogen, J. A.; Macchia, Marco
Synthesis and AT1 affinity evaluation of benzamidophenyl analogs of known AT1 receptor ligands with similar aromatic skeleton
2008-01-01 Rapposelli, Simona; Cuboni, S; Digiacomo, Maria; Lapucci, Annalina; Trincavelli, MARIA LETIZIA; Tuccinardi, Tiziano; Balsamo, A.
Titolo | Data di pubblicazione | Autore(i) | File |
---|---|---|---|
Locking PDK1 in DFG-out conformation through 2-oxo-indole containing molecules: Another tools to fight glioblastoma | 1-gen-2016 | Sestito, Simona; Daniele, Simona; Nesi, Giulia; Zappelli, Elisa; Di Maio, D; Marinelli, L; Digiacomo, Maria; Lapucci, Annalina; Martini, Claudia; Novellino, E; Rapposelli, Simona | |
Synthesis and In Vivo Imaging of N-(3-[11C]Methoxybenzyl)-2-(3-Methoxyphenyl)ethylaniline as a Potential Targeting Agent for P-glycoprotein | 1-gen-2016 | Petroni, Debora; Bartoli, Antonietta; Rapposelli, Simona; Digiacomo, Maria; Burchielli, Silvia; Nesi, Giulia; Lapucci, Annalina; Pardini, Silvia; Fucci, Sabrina; Macchia, Marco; Salvadori, Piero A.; Menichetti, Luca | |
Design and synthesis of 2-oxindole based multi-targeted inhibitors of PDK1/Akt signaling pathway for the treatment of glioblastoma multiforme | 1-gen-2015 | Sestito, Simona; Nesi, Giulia; Daniele, Simona; Martelli, Alma; Digiacomo, Maria; Borghini, Alice; Pietra, Daniele; Calderone, Vincenzo; Lapucci, Annalina; Falasca, Marco; Parrella, Paola; Notarangelo, Angelantonio; Breschi, MARIA CRISTINA; Macchia, Marco; Martini, Claudia; Rapposelli, Simona | |
Synthesis and evaluation of multi-functional NO-donor/insulin-secretagogue derivatives for the treatment of type II diabetes and its cardiovascular complications | 1-gen-2015 | Digiacomo, Maria; Martelli, Alma; Testai, Lara; Lapucci, Annalina; Breschi, MARIA CRISTINA; Calderone, Vincenzo; Rapposelli, Simona | |
Synthesis and pharmacological evaluation of multifunctional tacrine derivatives against several disease pathways of AD | 1-gen-2015 | Digiacomo, Maria; Chen, Ziwei; Wang, Shengnan; Lapucci, Annalina; Macchia, Marco; Yang, Xiaohong; Chu, Jiaqi; Han, Yifan; Pi, Rongbiao; Rapposelli, Simona | |
SAR study on arylmethyloxyphenyl scaffold: Looking for a P-gp nanomolar affinity | 1-gen-2014 | Nesi, Giulia; Colabufo, N. A.; Contino, M.; Perrone, M. G.; Digiacomo, Maria; Perrone, R.; Lapucci, Annalina; Macchia, Marco; Rapposelli, Simona | |
Synthesis and biological evaluation of (Hetero)aryl-methyloxyphenyl derivatives as potent P-glycoprotein modulating agents. | 1-gen-2013 | Nesi, Giulia; Colabufo, N. A.; Contino, M.; Perrone, M. G.; Digiacomo, Maria; Perrone, R.; Lapucci, Annalina; Macchia, Marco; Rapposelli, Simona | |
Synthesis of Novel 3,5-Disubstituted-2-oxindole Derivatives As Antitumor Agents against Human Nonsmall Cell Lung Cancer | 1-gen-2013 | Nesi, Giulia; Sestito, Simona; Mey, V.; Ricciardi, S.; Falasca, M.; Danesi, Romano; Lapucci, Annalina; Breschi, MARIA CRISTINA; Fogli, Stefano; Rapposelli, Simona | |
Targeting the upregulated PI3K-PDK1-Akt pathway: a drug discovery approach of treating cancer. | 1-gen-2012 | Nesi, Giulia; Danesi, Romano; Lapucci, Annalina; Ricciardi, S; Sestito, Simona; Rapposelli, Simona | |
Synthesis and Biological Evaluation of 2'-Oxo-2,3-dihydro-3'H-spiro[chromene-4,5'-[1,3]oxazolidin]3'il]acetic Acid Derivatives as Aldose reductase Inhibitors | 1-gen-2011 | Rapposelli, Simona; DA SETTIMO PASSETTI, Federico; Digiacomo, Maria; LA MOTTA, Concettina; Lapucci, Annalina; Sartini, Stefania; Vanni, M. | |
Synthesis, molecular docking and binding studies of selective serotonin transporter inhibitors | 1-gen-2011 | Nencetti, Susanna; Mazzoni, MARIA ROSA; Ortore, GABRIELLA MARIA PIA; Lapucci, Annalina; Giuntini, Janette; Orlandini, Elisabetta; Banti, Irene; Nuti, Elisa; Lucacchini, Antonio; Giannaccini, Gino; Rossello, Armando | |
Therapeutic potential of sulindac hydroxamic acid against human pancreatic and colonic cancer cells | 1-gen-2010 | Fogli, Stefano; Banti, I; Stefanelli, Fabio; Picchianti, L; Digiacomo, Maria; Macchia, Marco; Breschi, MARIA CRISTINA; Lapucci, Annalina | |
In vitro investigation of sulindac derivatives as potential anticancer agents | 1-gen-2009 | Fogli, Stefano; Banti, I; Digiacomo, Maria; Macchia, Marco; Lapucci, Annalina; Breschi, MARIA CRISTINA | |
Novel Transthyretin Amyloid Fibril Formation Inhibitors: Synthesis, Biological Evaluation, and X-Ray Structural Analysis | 1-gen-2009 | Palaninathan, S. K.; Mohamedmohaideen, N. N.; Orlandini, Elisabetta; Ortore, GABRIELLA MARIA PIA; Nencetti, Susanna; Lapucci, Annalina; Rossello, Armando; FREUNDLINCH JL, S; Sacchettini, J. C. | |
Synthesis and in-vitro antitumour activity of new naphthyridine derivatives on human pancreatic cancer cells | 1-gen-2009 | Banti, I; Nencetti, Susanna; Orlandini, Elisabetta; Lapucci, Annalina; Breschi, MARIA CRISTINA; Fogli, Stefano | |
Allosteric inhibition of (125I) ET-1 binding to ET(A) receptors by aldoxime and hydroxamic acid derivatives | 1-gen-2008 | Ahmed, M; Nencetti, Susanna; Mazzoni, MARIA ROSA; Porchia, F; Antonelli, F; Lapucci, Annalina | |
Allosteric inhibition of ET-1 binding to ETA receptors by aldoxime derivatives | 1-gen-2008 | Ahmed, Musa; Nencetti, Susanna; Mazzoni, MARIA ROSA; Porchia, Francesca; Antonelli, Federica; Lapucci, Annalina | |
Inhibition of [125] ET-1 binding to ETA receptors by salicilic acid dimers | 1-gen-2008 | Musa, Ahmed; Nencetti, Susanna; Mazzoni, MARIA ROSA; Francesca, Porchia; Federica, Antonelli; Lapucci, Annalina | |
Monoaryl-substituted Salicylaldoximes as Ligands for Estrogen Receptor Beta | 1-gen-2008 | Minutolo, Filippo; Bellini, R; Bertini, Simone; Carboni, I; Lapucci, Annalina; Pistolesi, L; Prota, G; Rapposelli, Simona; Solati, F; Tuccinardi, Tiziano; Martinelli, Adriano; Stossi, F; Carlson, K. E.; Katzenellenbogen, B. S.; Katzenellenbogen, J. A.; Macchia, Marco | |
Synthesis and AT1 affinity evaluation of benzamidophenyl analogs of known AT1 receptor ligands with similar aromatic skeleton | 1-gen-2008 | Rapposelli, Simona; Cuboni, S; Digiacomo, Maria; Lapucci, Annalina; Trincavelli, MARIA LETIZIA; Tuccinardi, Tiziano; Balsamo, A. |