RAPPOSELLI, SIMONA
 Distribuzione geografica
Continente #
NA - Nord America 1.855
EU - Europa 787
AS - Asia 426
AF - Africa 35
SA - Sud America 20
OC - Oceania 11
Continente sconosciuto - Info sul continente non disponibili 1
Totale 3.135
Nazione #
US - Stati Uniti d'America 1.790
IT - Italia 337
CN - Cina 225
FR - Francia 135
DE - Germania 66
IN - India 56
CA - Canada 55
VN - Vietnam 50
GB - Regno Unito 40
SE - Svezia 32
AT - Austria 30
ZA - Sudafrica 25
NL - Olanda 20
CZ - Repubblica Ceca 19
RU - Federazione Russa 18
JP - Giappone 15
HK - Hong Kong 13
KR - Corea 13
PL - Polonia 13
BR - Brasile 12
ES - Italia 12
FI - Finlandia 10
GR - Grecia 10
SG - Singapore 10
AU - Australia 9
IE - Irlanda 9
MX - Messico 9
PK - Pakistan 8
PT - Portogallo 8
UA - Ucraina 8
CL - Cile 6
EG - Egitto 6
IR - Iran 6
RO - Romania 6
TW - Taiwan 6
ID - Indonesia 5
TR - Turchia 4
IL - Israele 3
LT - Lituania 3
SA - Arabia Saudita 3
BD - Bangladesh 2
BE - Belgio 2
CH - Svizzera 2
CO - Colombia 2
HU - Ungheria 2
LU - Lussemburgo 2
MA - Marocco 2
MO - Macao, regione amministrativa speciale della Cina 2
NG - Nigeria 2
NZ - Nuova Zelanda 2
SI - Slovenia 2
UZ - Uzbekistan 2
AE - Emirati Arabi Uniti 1
EU - Europa 1
HN - Honduras 1
IQ - Iraq 1
NO - Norvegia 1
TH - Thailandia 1
Totale 3.135
Città #
Serra 153
Fairfield 151
Houston 137
Buffalo 122
Santa Cruz 120
Ashburn 116
Seattle 104
Woodbridge 84
Ann Arbor 64
Cambridge 50
Dallas 47
Chicago 43
Wilmington 40
Los Angeles 33
Dong Ket 32
Stockholm 28
Las Vegas 27
Shanghai 27
Beijing 26
Paris 26
Pisa 25
Garbagnate Milanese 23
Muizenberg 23
Vienna 23
Mountain View 22
Ottawa 22
Wuhan 21
San Diego 20
Florence 15
Guangzhou 15
University Park 15
Bengaluru 14
Boardman 13
Council Bluffs 13
Hangzhou 12
New York 12
Warsaw 12
Washington 12
Milan 11
Des Moines 9
Dublin 9
San Francisco 9
Helsinki 8
London 8
Toronto 8
Chengdu 7
Nanjing 7
Phoenix 7
Atlanta 6
Brampton 6
Crugers 6
Fort Worth 6
Henderson 6
Naples 6
St Helens 6
Tokyo 6
Boulder 5
Clearwater 5
Den Haag 5
Lanzhou 5
Madrid 5
Provo 5
San Jose 5
Austin 4
Brooklyn 4
Central 4
Delhi 4
Grenoble 4
Herndon 4
Lombard 4
Lucca 4
Lucknow 4
Madison 4
Napoli 4
Saint Petersburg 4
Seoul 4
Shenyang 4
Taipei 4
Belluno 3
Belo Horizonte 3
Bologna 3
Catania 3
Dongguan 3
Edinburgh 3
Esslingen am Neckar 3
Fleming Island 3
Frankfurt am Main 3
Genoa 3
Halifax 3
Hefei 3
Hyderabad 3
Milpitas 3
Mumbai 3
Murlo 3
Nanchang 3
Parsippany 3
Portland 3
Porto 3
Riva 3
Scottsdale 3
Totale 2.034
Nome #
Oxidative stress, mitochondrial abnormalities and proteins deposition: multitarget approaches in Alzheimer's disease, file e0d6c92c-5abc-fcf8-e053-d805fe0aa794 362
Dual inhibition of PDK1 and Aurora Kinase A: an effective strategy to induce differentiation and apoptosis of human glioblastoma multiforme stem cells, file e0d6c92e-f6de-fcf8-e053-d805fe0aa794 295
Nature-based molecules combined with rivastigmine: A symbiotic approach for the synthesis of new agents against Alzheimer's disease, file e0d6c929-bd94-fcf8-e053-d805fe0aa794 227
New Insights into the Potential Roles of 3-Iodothyronamine (T1AM) and Newly Developed Thyronamine-Like TAAR1 Agonists in Neuroprotection, file e0d6c929-caba-fcf8-e053-d805fe0aa794 174
Sulfonamido-derivatives of unsubstituted carbazoles as BACE1 inhibitors, file e0d6c92b-83c0-fcf8-e053-d805fe0aa794 161
Preclinical validation of 3-phosphoinositide-dependent protein kinase 1 inhibition in pancreatic cancer, file e0d6c92d-71e3-fcf8-e053-d805fe0aa794 133
Synthesis and functional evaluation of novel aldose reductase inhibitors bearing a spirobenzopyran scaffold, file e0d6c928-e3c9-fcf8-e053-d805fe0aa794 128
A Novel H2S-releasing Amino-Bisphosphonate which combines bone anti-catabolic and anabolic functions, file e0d6c929-8fd2-fcf8-e053-d805fe0aa794 128
Mitochondrial Potassium Channels as Pharmacological Target for Cardioprotective Drugs, file e0d6c92b-a678-fcf8-e053-d805fe0aa794 121
Development of Classification Models for Identifying “True” P-glycoprotein (P-gp) Inhibitors Through Inhibition, ATPase Activation and Monolayer Efflux Assays, file e0d6c929-fdcd-fcf8-e053-d805fe0aa794 113
Combined inhibition of AKT/mTOR and MDM2 enhances Glioblastoma Multiforme cell apoptosis and differentiation of cancer stem cells, file e0d6c929-17ee-fcf8-e053-d805fe0aa794 111
Salicylaldoximes and anthranylaldoximes as alternatives to phenol-based estrogen receptor ligands, file e0d6c92a-bf4d-fcf8-e053-d805fe0aa794 107
Hydrogen sulfide: A worthwhile tool in the design of new multitarget drugs, file e0d6c929-bd95-fcf8-e053-d805fe0aa794 97
Iminothioethers as Hydrogen Sulfide Donors: From the Gasotransmitter Release to the Vascular Effects, file e0d6c92b-82e4-fcf8-e053-d805fe0aa794 95
New Multitarget Approaches in the War Against Glioblastoma: A Mini-Perspective, file e0d6c92b-35e4-fcf8-e053-d805fe0aa794 89
A novel approach in glioblastoma multiforme drug discovery: Perturbation studies in vitro, file e0d6c92d-74a4-fcf8-e053-d805fe0aa794 82
Synthesis and anti-glioblastoma effects of artemisinin-isothiocyanate derivatives, file e0d6c92b-2588-fcf8-e053-d805fe0aa794 80
Epibatidine: A Promising Natural Alkaloid in Health, file e0d6c92b-2e41-fcf8-e053-d805fe0aa794 79
Dual PDK1/aurora kinase a inhibitors reduce pancreatic cancer cell proliferation and colony formation, file e0d6c92d-fb07-fcf8-e053-d805fe0aa794 73
Design and synthesis of 2-oxindole based multi-targeted inhibitors of PDK1/Akt signaling pathway for the treatment of glioblastoma multiforme, file e0d6c92b-ba21-fcf8-e053-d805fe0aa794 72
Memantine prodrug as a new agent for alzheimer’s disease, file e0d6c92d-6558-fcf8-e053-d805fe0aa794 71
Editorial: Multi-Target-Directed Ligands (MTDL) as Challenging Research Tools in Drug Discovery: From Design to Pharmacological Evaluation, file e0d6c92c-2c2c-fcf8-e053-d805fe0aa794 62
The pleiotropic functionality of endogenous 3-iodothyronamine (T1AM) and synthetic thyronamine-like analogs: a powerful tool to target interlinked diseases such as obesity and neurodegeneration, file a5e0d36a-d6b8-4307-aef2-9bbb2653aafe 57
A patent update on PDK1 inhibitors (2015-present), file e0d6c92d-4751-fcf8-e053-d805fe0aa794 49
null, file e0d6c92d-d330-fcf8-e053-d805fe0aa794 44
Synthesis and evaluation of multi-functional NO-donor/insulin-secretagogue derivatives for the treatment of type II diabetes and its cardiovascular complications, file e0d6c92b-add9-fcf8-e053-d805fe0aa794 40
PHARMACEUTICAL COMBINATION FOR THE TREATMENT OF TUMORS, file e0d6c927-e2d8-fcf8-e053-d805fe0aa794 36
NEW MOLECULES FOR BONE TISSUE REGENERATION, file e0d6c927-e14d-fcf8-e053-d805fe0aa794 26
Mitochondrial Potassium Channels as Pharmacological Target for Cardioprotective Drugs, file e0d6c929-1779-fcf8-e053-d805fe0aa794 10
Breakthroughs in medicinal chemistry: New targets and mechanisms, new drugs, new hopes-7, file e0d6c92f-9a0c-fcf8-e053-d805fe0aa794 8
Lipolytic effects of 3-iodothyronamine (T1AM) and a novel thyronamine-like analog SG-2 through the AMPK pathway, file e0d6c930-2967-fcf8-e053-d805fe0aa794 7
null, file e0d6c927-1f67-fcf8-e053-d805fe0aa794 6
null, file e0d6c928-0af0-fcf8-e053-d805fe0aa794 6
Sulfonamido-derivatives of unsubstituted carbazoles as BACE1 inhibitors, file e0d6c92b-7d41-fcf8-e053-d805fe0aa794 6
Endogenous 3-iodothyronamine (T1Am) and synthetic thyronamine-like analog SG-2 act as novel pleiotropic neuroprotective agents through the modulation of SIRT6, file e0d6c92e-cf97-fcf8-e053-d805fe0aa794 6
Synthesis and pharmacological evaluation of multifunctional tacrine derivatives against several disease pathways of AD, file e0d6c926-4c50-fcf8-e053-d805fe0aa794 5
Synthesis and evaluation of multi-functional NO-donor/insulin-secretagogue derivatives for the treatment of type II diabetes and its cardiovascular complications, file e0d6c929-1c3d-fcf8-e053-d805fe0aa794 5
null, file e0d6c928-213e-fcf8-e053-d805fe0aa794 4
Synthesis and Biological Evaluation of Cyclopropylamine Vitamin D‐Like CYP24A1 Inhibitors, file e0d6c929-aaf4-fcf8-e053-d805fe0aa794 4
2-OXO-1,2-DIHYDROPYRIDINE-3-CARBOXAMIDE COMPOUNDS AND THEIR USE AS INHIBITORS OF PDK1 (US Patent App. 15/735,468, 2018), file e0d6c92b-6aae-fcf8-e053-d805fe0aa794 4
Investigating curcumin/intestinal epithelium interaction in a millifluidic bioreactor, file e0d6c92f-ed05-fcf8-e053-d805fe0aa794 4
Synthesis of Novel 3,5-Disubstituted-2-oxindole Derivatives As Antitumor Agents against Human Nonsmall Cell Lung Cancer, file e0d6c926-4359-fcf8-e053-d805fe0aa794 3
Synthetic analogues of 3-iodothyronamine (T1AM) and uses thereof., file e0d6c927-1956-fcf8-e053-d805fe0aa794 3
Locking PDK1 in DFG-out conformation through 2-oxo-indole containing molecules: Another tools to fight glioblastoma, file e0d6c927-6d41-fcf8-e053-d805fe0aa794 3
Iminothioethers as Hydrogen Sulfide Donors: From the Gasotransmitter Release to the Vascular Effects, file e0d6c929-afb4-fcf8-e053-d805fe0aa794 3
SG-2: A promising lipolytic and pro-autophagic hit-compound to treat Alzheimer’s disease, file e0d6c92f-dd2e-fcf8-e053-d805fe0aa794 3
Synthesis and pharmacological evaluation of multifunctional tacrine derivatives against several disease pathways of AD, file e0d6c930-8839-fcf8-e053-d805fe0aa794 3
Diphenyl-methane based thyromimetic inhibitors for transthyretin amyloidosis, file e0d6c931-4ba8-fcf8-e053-d805fe0aa794 3
null, file e0d6c931-8b9a-fcf8-e053-d805fe0aa794 3
Paving Luteolin Therapeutic Potentialities and Agro-Food-Pharma Applications: Emphasis on in Vivo Pharmacological Effects and Bioavailability Traits, file e0d6c931-9088-fcf8-e053-d805fe0aa794 3
Chitosan nanoparticles as a promising tool in nanomedicine with particular emphasis on oncological treatment, file e0d6c931-a4df-fcf8-e053-d805fe0aa794 3
Multi-Target Mechanisms of Phytochemicals in Alzheimer's Disease: Effects on Oxidative Stress, Neuroinflammation and Protein Aggregation, file 4b21a3b2-30af-4954-a32b-9ad923faa76f 2
Design, synthesis and biological evaluation of novel orthosteric-allosteric ligands of the cannabinoid receptor type 2 (CB2R), file 4df2cc93-2fae-4e84-93fa-a2e883a1120f 2
Novel adenosine 5'-triphosphate-sensitive potassium channel ligands: a patent overview (2005 - 2010), file e0d6c926-0c3e-fcf8-e053-d805fe0aa794 2
Synthesis and In Vivo Imaging of N-(3-[11C]Methoxybenzyl)-2-(3-Methoxyphenyl)ethylaniline as a Potential Targeting Agent for P-glycoprotein, file e0d6c929-19f4-fcf8-e053-d805fe0aa794 2
Design and synthesis of 2-oxindole based multi-targeted inhibitors of PDK1/Akt signaling pathway for the treatment of glioblastoma multiforme, file e0d6c929-1c15-fcf8-e053-d805fe0aa794 2
Collecting data through high throughput in vitro early toxicity and off-target liability assays to rapidly identify limitations of novel thyromimetics, file e0d6c92f-8eeb-fcf8-e053-d805fe0aa794 2
Potential role of two novel agonists of thyroid hormone receptor-β on liver regeneration, file e0d6c92f-b20d-fcf8-e053-d805fe0aa794 2
Turmeric and Its Major Compound Curcumin on Health: Bioactive Effects and Safety Profiles for Food, Pharmaceutical, Biotechnological and Medicinal Applications, file e0d6c92f-ecde-fcf8-e053-d805fe0aa794 2
null, file e0d6c930-b98d-fcf8-e053-d805fe0aa794 2
TG68, a Novel Thyroid Hormone Receptor-β Agonist for the Treatment of NAFLD, file e0d6c931-5fb1-fcf8-e053-d805fe0aa794 2
Editorial: Protein-Protein Interactions: Drug Discovery for the Future, file e0d6c931-749b-fcf8-e053-d805fe0aa794 2
14-3-3 PROTEIN MODULATORS AS ANTITUMOR AGENTS, file 9b0835c8-60a6-493d-9269-a4b8851561c7 1
Editorial: New insights into the mechanisms of resistance to anti-cancer drugs, file a189601c-0e34-4b2f-9d61-c4c3a4a588e2 1
Potential use of TG68 - A novel thyromimetic - for the treatment of non-alcoholic fatty liver (NAFLD)-associated hepatocarcinogenesis, file d3aff175-77a6-4881-b7ba-dd844209a932 1
Design, synthesis and pharmacological evaluation of novel tacrine-caffeic acid hybrids as multi-targeted compounds against Alzheimer's disease, file e0d6c926-15bb-fcf8-e053-d805fe0aa794 1
Synthesis of a Resveratrol Analogue with High Ceramide-Mediated Proapoptotic Activity on Human Breast Cancer Cells, file e0d6c926-2ab3-fcf8-e053-d805fe0aa794 1
2-[(3-Methoxyphenylethyl)phenoxy]-based ABCB1 inhibitors: effect of different basic side-chains on their biological properties, file e0d6c926-2e79-fcf8-e053-d805fe0aa794 1
Discovery of novel N-substituted carbazoles as neuroprotective agents with potent anti-oxidative activity, file e0d6c926-3ff2-fcf8-e053-d805fe0aa794 1
SAR study on arylmethyloxyphenyl scaffold: Looking for a P-gp nanomolar affinity, file e0d6c926-4090-fcf8-e053-d805fe0aa794 1
Antiarrhythmic activity of a new spiro-cyclic benzopyran activator of the cardiac mitochondrial ATP dependent potassium channels, file e0d6c927-dc7f-fcf8-e053-d805fe0aa794 1
SYNTHESIS AND BIOLOGICAL EVALUATION OF 5-MEMBERED SPIRO HETEROCYCLE-BENZIPYRAN DERIVATIVES AGAINST MYOCARDIAL ISCHEMIA, file e0d6c929-1dad-fcf8-e053-d805fe0aa794 1
Tacrine-6-Ferulic Acid, a Novel Multifunctional Dimer Against Alzheimer's Disease, Prevents Oxidative Stress-Induced Neuronal Death Through Activating Nrf2/ARE/HO-1 Pathway in HT22 Cells, file e0d6c929-2588-fcf8-e053-d805fe0aa794 1
Synthesis and Biological Evaluation of 2'-Oxo-2,3-dihydro-3'H-spiro[chromene-4,5'-[1,3]oxazolidin]3'il]acetic Acid Derivatives as Aldose reductase Inhibitors, file e0d6c929-2a4d-fcf8-e053-d805fe0aa794 1
Synthesis and biological activities of vitamin D-like inhibitors of CYP24 hydroxylase, file e0d6c929-2b79-fcf8-e053-d805fe0aa794 1
Editorial: Effect of Stereochemistry in Medicinal Chemistry and Drug Discovery, file e0d6c929-2e07-fcf8-e053-d805fe0aa794 1
A review on the hybrids of hydroxycinnamic acid as multi-target-directed ligands against Alzheimer's disease, file e0d6c92b-a77b-fcf8-e053-d805fe0aa794 1
Nature-based molecules combined with rivastigmine: A symbiotic approach for the synthesis of new agents against Alzheimer's disease, file e0d6c92c-5ab6-fcf8-e053-d805fe0aa794 1
null, file e0d6c930-6add-fcf8-e053-d805fe0aa794 1
null, file e0d6c930-cc12-fcf8-e053-d805fe0aa794 1
Beyond antioxidant effects: Nature-based templates unveil new strategies for neurodegenerative diseases, file e0d6c931-5bf2-fcf8-e053-d805fe0aa794 1
Late breaker posters, file e0d6c931-7414-fcf8-e053-d805fe0aa794 1
Abstract 1294: Dual targeting of PDK1 and Aurora A using first-in class OXID-pyridonyl compounds in preclinical models of Ewing sarcoma, file e0d6c931-a0bc-fcf8-e053-d805fe0aa794 1
Design, Synthesis, and In Vitro Evaluation of Novel 8-Amino-Quinoline Combined with Natural Antioxidant Acids, file fc9ef2e6-1522-44ee-b3c4-b002f2b1fe10 1
Totale 3.261
Categoria #
all - tutte 6.761
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 6.761


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/2019105 0 0 0 0 0 0 0 5 16 19 37 28
2019/2020413 43 14 26 28 22 27 19 22 32 81 58 41
2020/2021681 49 62 27 54 42 70 51 46 97 45 69 69
2021/2022791 77 28 50 112 94 52 50 44 41 26 163 54
2022/2023720 32 58 130 89 45 31 46 75 61 48 47 58
2023/2024450 49 33 53 32 93 105 65 20 0 0 0 0
Totale 3.261