CINECA IRIS Institutional Research Information System

RAPPOSELLI, SIMONA
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
NA - Nord America 15.592
AS - Asia 7.893
EU - Europa 7.112
SA - Sud America 1.053
AF - Africa 311
OC - Oceania 19
Continente sconosciuto - Info sul continente non disponibili 5
Totale 31.985
Salva come PNG Salva come JPEG
Nazione #
US - Stati Uniti d'America 15.128
IT - Italia 2.531
SG - Singapore 2.491
CN - Cina 2.287
HK - Hong Kong 1.179
SE - Svezia 1.010
DE - Germania 948
BR - Brasile 877
VN - Vietnam 675
BG - Bulgaria 518
FR - Francia 469
CA - Canada 382
TR - Turchia 374
GB - Regno Unito 318
FI - Finlandia 302
RU - Federazione Russa 253
JP - Giappone 186
AT - Austria 184
IN - India 179
UA - Ucraina 161
CI - Costa d'Avorio 96
KR - Corea 95
PL - Polonia 89
BD - Bangladesh 73
CH - Svizzera 73
NL - Olanda 68
AR - Argentina 50
BE - Belgio 46
IQ - Iraq 45
MX - Messico 42
SN - Senegal 39
SA - Arabia Saudita 38
CZ - Repubblica Ceca 37
ZA - Sudafrica 36
ES - Italia 34
ID - Indonesia 33
NG - Nigeria 33
MA - Marocco 31
PK - Pakistan 29
PH - Filippine 27
VE - Venezuela 26
UZ - Uzbekistan 25
CO - Colombia 24
EC - Ecuador 19
MY - Malesia 19
IL - Israele 18
AU - Australia 17
CL - Cile 17
EG - Egitto 17
LT - Lituania 15
JO - Giordania 14
PE - Perù 13
PY - Paraguay 12
IR - Iran 11
KE - Kenya 11
NP - Nepal 10
UY - Uruguay 10
DZ - Algeria 9
TN - Tunisia 9
AE - Emirati Arabi Uniti 8
AZ - Azerbaigian 8
JM - Giamaica 8
KZ - Kazakistan 8
TH - Thailandia 8
TW - Taiwan 8
LB - Libano 7
OM - Oman 7
BJ - Benin 6
CR - Costa Rica 6
IE - Irlanda 6
KH - Cambogia 6
PA - Panama 6
BB - Barbados 5
DK - Danimarca 5
DO - Repubblica Dominicana 5
GR - Grecia 5
PS - Palestinian Territory 5
RO - Romania 5
AL - Albania 4
BO - Bolivia 4
GA - Gabon 4
GE - Georgia 4
GH - Ghana 4
LK - Sri Lanka 4
NO - Norvegia 4
PT - Portogallo 4
AO - Angola 3
EE - Estonia 3
EU - Europa 3
LV - Lettonia 3
MK - Macedonia 3
NI - Nicaragua 3
RS - Serbia 3
TT - Trinidad e Tobago 3
A1 - Anonimo 2
BH - Bahrain 2
BW - Botswana 2
CG - Congo 2
CY - Cipro 2
ET - Etiopia 2
Totale 31.952
Salva come PNG Salva come JPEG
Città #
Ashburn 1.678
Woodbridge 1.545
Singapore 1.417
Hong Kong 1.152
Fairfield 1.046
Ann Arbor 964
Chandler 921
Houston 907
Santa Clara 736
San Jose 735
Dallas 724
Serra 675
Shanghai 591
Milan 536
Sofia 518
Beijing 517
Seattle 442
Wilmington 370
Cambridge 349
New York 322
Ottawa 306
Boardman 291
Princeton 245
Izmir 244
Los Angeles 241
Lawrence 202
Jacksonville 188
Lauterbourg 185
Medford 178
Tokyo 172
Vienna 170
Ho Chi Minh City 159
Pisa 158
Nanjing 154
Council Bluffs 146
Frankfurt am Main 129
Des Moines 128
Hefei 123
Hanoi 119
Chicago 99
Rome 98
Abidjan 96
Helsinki 94
Redondo Beach 91
Istanbul 89
London 86
Dong Ket 79
Munich 79
Florence 77
Seoul 77
Redwood City 76
Marseille 75
Dearborn 74
São Paulo 72
Warsaw 72
Nanchang 71
Buffalo 69
San Diego 61
Bern 50
Orem 48
Shenyang 48
Boulder 45
Brussels 44
The Dalles 44
Columbus 41
Dakar 39
Ogden 39
Tianjin 38
Turku 38
Nürnberg 37
Norwalk 36
Hebei 35
Lucca 35
Da Nang 34
Rio de Janeiro 34
Lagos 31
Nuremberg 31
San Francisco 31
Bremen 30
Brno 30
Carrara 30
Hangzhou 28
Livorno 28
Pescara 28
Phoenix 28
Pune 28
Toronto 28
Belo Horizonte 27
Changsha 26
Fort Wayne 26
Kunming 26
Amsterdam 25
Washington 25
Genoa 24
Auburn Hills 23
Düsseldorf 23
Fuzhou 23
Jüchen 23
Montreal 23
Paris 23
Totale 22.571
Salva come PNG Salva come JPEG
Nome #
2-OXO-1,2-DIHYDROPYRIDINE-3-CARBOXAMIDE COMPOUNDS AND THEIR USE AS INHIBITORS OF PDK1 (US Patent App. 15/735,468, 2018) 308
Design and synthesis of 2-oxindole based multi-targeted inhibitors of PDK1/Akt signaling pathway for the treatment of glioblastoma multiforme 300
2-OXO-1,2-DIHYDROPYRIDINE-3-CARBOXAMIDE COMPOUNDS AND THEIR USE AS DUAL INHIBITORS OF PDK1/AURA 299
Iminothioethers as Hydrogen Sulfide Donors: From the Gasotransmitter Release to the Vascular Effects 296
Synthesis of Novel 3,5-Disubstituted-2-oxindole Derivatives As Antitumor Agents against Human Nonsmall Cell Lung Cancer 287
A patent update on PDK1 inhibitors (2015-present) 280
Multifunctional Drugs: New challenging chimeras in medicinal chemistry and drug discovery 241
Nature-based molecules combined with rivastigmine: A symbiotic approach for the synthesis of new agents against Alzheimer's disease 240
Locking PDK1 in DFG-out conformation through 2-oxo-indole containing molecules: Another tools to fight glioblastoma 234
Synthesis and evaluation of multi-functional NO-donor/insulin-secretagogue derivatives for the treatment of type II diabetes and its cardiovascular complications 230
Dual inhibition of PDK1 and Aurora Kinase A: an effective strategy to induce differentiation and apoptosis of human glioblastoma multiforme stem cells 227
Combined inhibition of AKT/mTOR and MDM2 enhances Glioblastoma Multiforme cell apoptosis and differentiation of cancer stem cells 226
Memantine prodrug as a new agent for alzheimer’s disease 222
New NO-Releasing Pharmacodynamic Hybrids of Losartan and Its Active Metabolite: Design,Synthesis, and Biopharmacological Properties 220
A NEW NITRIC OXIDE RELEASING ANTI-DIABETIC HYBRID DRUG: FROM THE DESIGN TO THE PHARMACOLOGICAL CHARACTERIZATION 214
Design, synthesis and pharmacological evaluation of novel tacrine-caffeic acid hybrids as multi-targeted compounds against Alzheimer's disease 212
Synthesis of Anthranylaldoxime Derivatives as Estrogen Receptor Ligands and Computational Prediction of Binding Modes 205
Synthesis and AT1 affinity evaluation of benzamidophenyl analogs of known AT1 receptor ligands with similar aromatic skeleton 205
Arylthioamides as H2S Donors:l-Cysteine-Activated Releasing Properties and Vascular Effects in Vitro and in Vivo 202
Enantiopure 3-(arylmethylidene)aminoxy-2-methylpropionic acids: synthesis and antiinflammatory properties 201
In-vitro evaluation of new pharmacodynamic hybrids with insulin secretagogue and NO-donor activity 201
Synthesis and In Vivo Imaging of N-(3-[11C]Methoxybenzyl)-2-(3-Methoxyphenyl)ethylaniline as a Potential Targeting Agent for P-glycoprotein 200
Design, Synthesis, and Biological Activity of New CB2 Receptor Ligands: from Orthosteric and Allosteric Modulators to Dualsteric/Bitopic Ligands 200
Salicylaldoximes and anthranylaldoximes as alternatives to phenol-based estrogen receptor ligands 199
Synthesis of stable analogues of geranylgeranyl diphosphate possessing a (Z,E,E)-geranylgeranyl side chain, docking analysis, and biological assays for prenyl protein transferase inhibition 199
SAR study on arylmethyloxyphenyl scaffold: Looking for a P-gp nanomolar affinity 199
The pleiotropic functionality of endogenous 3-iodothyronamine (T1AM) and synthetic thyronamine-like analogs: a powerful tool to target interlinked diseases such as obesity and neurodegeneration 199
Salicylaldoximes and anthranylaldoximes as alternatives to phenol-based estrogen receptor ligands 198
Endogenous TH metabolite 3-iodothyronamine (T1AM) and synthetic thyronamine-like analogues SG-1 and SG-2 induce autophagy in human glioblastoma cells (U-87MG) 197
Design and synthesis of H2S-donor hybrids: A new treatment for Alzheimer's disease? 197
Dimer of rivastigmine and caffeic acid or ferulic acid, preparation method and drug composition thereof 195
Epibatidine: A Promising Natural Alkaloid in Health 195
Oxidative stress, mitochondrial abnormalities and proteins deposition: multitarget approaches in Alzheimer's disease 194
Phosphonomethylphosphorylmethyl(oxy)-analogues of geranylgeranyl diphosphate as stable and selective geranylgeranyl protein transferase inhibitors 192
Development of Classification Models for Identifying “True” P-glycoprotein (P-gp) Inhibitors Through Inhibition, ATPase Activation and Monolayer Efflux Assays 190
Sulfonamido-derivatives of unsubstituted carbazoles as BACE1 inhibitors 189
Design, Synthesis, and In Vitro Evaluation of Novel 8-Amino-Quinoline Combined with Natural Antioxidant Acids 189
Synthesis and In Vitro Characterization of Selective Cannabinoid CB2 Receptor Agonists: Biological Evaluation against Neuroblastoma Cancer Cells 186
Spirocyclic Benzopyran-based derivatives as new anti-ischemic activators of mitochondrial ATP-sensitive potassium channel 186
Pharmacological study on the cardiovascular activity of no-sartans, pharmacodynamic hybridsexhibiting at1-antagonist and no-donor properties 185
New Insights into the Potential Roles of 3-Iodothyronamine (T1AM) and Newly Developed Thyronamine-Like TAAR1 Agonists in Neuroprotection 185
Synthesis and biological activities of vitamin D-like inhibitors of CYP24 hydroxylase 184
Synthesis and functional evaluation of novel aldose reductase inhibitors bearing a spirobenzopyran scaffold 184
New Insights into Bitopic Orthosteric/Allosteric Ligands of Cannabinoid Receptor Type 2 182
Synthesis and 5-HT2A, 5-HT1Aand a1-Binding Affinities of 2-[2- Hydroxy-3-(pyridin-3-yl-methyl)amino]-, 2-[2-Hydroxy-3-(2- pyridin-2-yl-ethyl)amino]- and 2-[2-Hydroxy-3-(4-N-methylpiperazin- 1-yl)-amino]propoxybenzaldehyde-O-(substituted) Benzyl Oximes 181
ANTI-ISCHEMIC PROPERTIES OF A NEW SPIRO-CYCLIC BENZOPYRAN ACTIVATOR OF CARDIAC MITOCHONDRIAL ATP-SENSITIVE POTASSIUM CHANNELS 179
Dual PDK1/aurora kinase a inhibitors reduce pancreatic cancer cell proliferation and colony formation 179
New Benzopyran-Based Openers of the Mitochondrial ATP-Sensitive Potassium Channel with Potent Anti-Ischemic Properties 178
Diaryl-substituted salicyl- and anthranyl-ketoximes as potential estrogen receptor ligands 178
2-[(3-Methoxyphenylethyl)phenoxy]-based ABCB1 inhibitors: effect of different basic side-chains on their biological properties 178
Endogenous 3-iodothyronamine (T1Am) and synthetic thyronamine-like analog SG-2 act as novel pleiotropic neuroprotective agents through the modulation of SIRT6 178
(E)-[2-(4-Methylsulphonylphenyl)-1-cyclopentenyl-1-methyliden]-(arylmethyloxy)amines. Methyleneaminoxymethyl (MAOM) analogues of diarylcyclopentenyl cyclooxygenase-2 inhibitors: synthesis and biological properties 176
Variously substituted (phosphonoacetamido)oxy analogues of geranylgeranyl diphosphate (GGdP) as GGdP-transferase (GGTase) inhibitors and antiproliferative agents 176
New N-arylsulfonyl-N-alkoxyaminoacetohydroxamic acids as selective inhibitors of gelatinase A (MMP-2) 175
Mitochondrial Potassium Channels as Pharmacological Target for Cardioprotective Drugs 174
NO-Sartans: A New Class of Pharmacodynamic Hybrids as Cardiovascular Drugs 173
A new development of matrix metalloproteinase inhibitors: twin hydroxamic acids as potent inhibitors of MMPs 172
Targeting the upregulated PI3K-PDK1-Akt pathway: a drug discovery approach of treating cancer. 170
Anti-ischemic properties of a new spiro-cyclic benzopyran activator of the cardiac mito-KATP channel 170
Tacrine-6-Ferulic Acid, a Novel Multifunctional Dimer Against Alzheimer's Disease, Prevents Oxidative Stress-Induced Neuronal Death Through Activating Nrf2/ARE/HO-1 Pathway in HT22 Cells 168
Synthesis of a Resveratrol Analogue with High Ceramide-Mediated Proapoptotic Activity on Human Breast Cancer Cells 168
New spiromorpholone- and spiromorpholine-benzopyrane derivatives as potential activators of mito-KATP channel 167
H2S-RELEASING PROPERTIES OF NEW THIOAMIDE, IMINOTHIOETHER AND ISOTHIOCYANATE DERIVATIVES 167
Iminothioethers as a novel class of H2S-donor: gasotransmitter release and vascular effects 167
Synthesis of aniline-type analogues of farnesyl diphosphate and their biological assays for prenyl protein transferase inhibitory activity 167
Novel adenosine 5'-triphosphate-sensitive potassium channel ligands: a patent overview (2005 - 2010) 166
Cardiac ATP-sensitive potassium channels, a potential target for an anti-ischaemic pharmacological strategy 166
Classification models for the identification of P-gp inhibitors 163
Hydrogen sulfide: A worthwhile tool in the design of new multitarget drugs 161
Design, synthesis and biological evaluation of novel TRβ selective agonists sustained by ADME-toxicity analysis 161
Symbiotic approach applied to the synthesis of new agents for the treatment of Alzheimer’s disease 160
Ceramide analogues in apoptosis: a new strategy for anticancer drug development 159
Antiarrhythmic activity of a new spiro-cyclic benzopyran activator of the cardiac mitochondrial ATP dependent potassium channels 159
Preclinical validation of 3-phosphoinositide-dependent protein kinase 1 inhibition in pancreatic cancer 159
Aryl-substituted methyleneaminoxymethyl (MAOM) analogues of diarylcyclopentenyl cyclooxygenase-2 inhibitors: effects of some structural modifications on their biological properties 157
Synthesis and biological evaluation of (Hetero)aryl-methyloxyphenyl derivatives as potent P-glycoprotein modulating agents. 157
SG‐2: A SYNTHETIC ANALOG OF THYROID HORMONE METABOLITE 3‐IODOTHYRONAMINE (T1AM), PREVENTS β‐AMYLOID NEUROTOXICITY IN VITRO 157
P-gp Transporter and its Role in Neurodegenerative Diseases 155
Discovery of novel N-substituted carbazoles as neuroprotective agents with potent anti-oxidative activity 155
Targeting autophagy impairment improves the phenotype of a novel CLN8 zebrafish model 152
Novel Estrogen Receptor Ligands Based on an Anthranylaldoxime Structure: Role of the Phenol-Type Pseudocycle in the Binding Process 152
Synthesis and pharmacological evaluation of multifunctional tacrine derivatives against several disease pathways of AD 152
Synthesis and prostaglandin synthase inhibitory activity of new aromatic O-alkyloxime ethers substituted with methylsulfonamido or methylsulfonyl groups on their aliphatic portion 150
Synthesis and Biological Evaluation of Cyclopropylamine Vitamin D‐Like CYP24A1 Inhibitors 150
Areca catechu—From farm to food and biomedical applications 150
Selective Thyroid Hormone Receptor-Beta (TRβ) Agonists: New Perspectives for the Treatment of Metabolic and Neurodegenerative Disorders 150
Aminobenzothiazoles as beta-Selective Estrogen Receptor Ligands 149
Synthesis, Antifungal Activity, and Molecular Modeling Studies of New Inverted Oxime Ethers of Oxiconazole 149
Multi-targeted ChEI-copper chelating molecules as neuroprotective agents 149
NO-glibenclamide derivatives: prototypes of a new class of nitric oxide-releasing anti-diabetic drugs 149
THIOAMIDE, IMINOTHIOETHER AND ISOTHIOCYANATE DERIVATIVES: CHEMOTYPES OF SLOW H2S-RELEASING AGENTS 148
Synthesis of new potent P-glycoprotein inhibitors and their screening: potential tools to reduce the multidrug resistance 146
Derivati arilpiperazinici quali inibitori della Glicoproteina-P (P-gp) utili nella Multidrug Resistance (MDR) indotta da chemioterapici 146
Classification models for the identification of P-gp inhibitors. 146
Evaluation of the NO-releasing properties of NO-donor linkers 146
Conformationally restrained ceramide analogues: effects of lipophilic modifications on the antiproliferative activity 146
New Multitarget Approaches in the War Against Glioblastoma: A Mini-Perspective 145
Synthesis and COX2 inhibitory properties of N-Phenyl-and N-benzyl-substituted amides of 2-(4-methylsulfonylphenyl)cyclopent-1-ene-1-carboxylic acid and of their pyrazole, thiophene, and isoxazole analogs 144
SUN-717 SG-2 a Novel Multi-Target Directed Ligand (MTDL) for the Treatment of Neurodegenerative Diseases (NDDS) 143
A Novel H2S-releasing Amino-Bisphosphonate which combines bone anti-catabolic and anabolic functions 142
Totale 18.454
Salva come PNG Salva come JPEG
Categoria #
all - tutte 88.162
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 88.162
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021474 0 0 0 0 0 0 0 0 0 120 94 260
2021/20222.354 33 185 69 126 379 317 89 127 72 90 142 725
2022/20233.180 382 393 218 260 323 462 19 220 617 35 162 89
2023/20242.483 323 281 277 167 337 387 137 46 29 84 92 323
2024/20256.579 55 311 136 384 553 628 718 357 644 871 695 1.227
2025/20267.198 536 897 780 575 852 730 1.339 344 533 612 0 0
Totale 32.563