CINECA IRIS Institutional Research Information System

RAPPOSELLI, SIMONA
 Distribuzione geografica
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Continente #
NA - Nord America 10.375
EU - Europa 5.637
AS - Asia 1.648
AF - Africa 168
SA - Sud America 19
OC - Oceania 16
Continente sconosciuto - Info sul continente non disponibili 5
Totale 17.868
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Nazione #
US - Stati Uniti d'America 10.051
IT - Italia 2.273
SE - Svezia 989
CN - Cina 880
DE - Germania 764
BG - Bulgaria 517
CA - Canada 322
TR - Turchia 253
VN - Vietnam 196
GB - Regno Unito 193
FR - Francia 172
FI - Finlandia 164
AT - Austria 157
UA - Ucraina 146
SG - Singapore 113
CI - Costa d'Avorio 95
HK - Hong Kong 80
RU - Federazione Russa 64
IN - India 62
CH - Svizzera 56
PL - Polonia 42
BE - Belgio 41
SN - Senegal 34
NG - Nigeria 29
NL - Olanda 24
JP - Giappone 16
AU - Australia 15
BR - Brasile 13
IR - Iran 9
KR - Corea 8
ES - Italia 7
IL - Israele 7
CL - Cile 5
CZ - Repubblica Ceca 4
EG - Egitto 4
GR - Grecia 4
PK - Pakistan 4
SA - Arabia Saudita 4
UZ - Uzbekistan 4
EU - Europa 3
IE - Irlanda 3
KZ - Kazakistan 3
NO - Norvegia 3
A1 - Anonimo 2
DK - Danimarca 2
HR - Croazia 2
ID - Indonesia 2
LK - Sri Lanka 2
MK - Macedonia 2
RO - Romania 2
RS - Serbia 2
TH - Thailandia 2
ZA - Sudafrica 2
BA - Bosnia-Erzegovina 1
BD - Bangladesh 1
CO - Colombia 1
CY - Cipro 1
DO - Repubblica Dominicana 1
DZ - Algeria 1
EE - Estonia 1
GH - Ghana 1
LB - Libano 1
MA - Marocco 1
MD - Moldavia 1
MX - Messico 1
NZ - Nuova Zelanda 1
PT - Portogallo 1
SC - Seychelles 1
Totale 17.868
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Città #
Woodbridge 1.545
Fairfield 1.046
Ann Arbor 964
Chandler 921
Houston 899
Serra 675
Ashburn 599
Milan 519
Sofia 517
Seattle 438
Beijing 378
Wilmington 369
Cambridge 349
Ottawa 305
New York 282
Princeton 245
Izmir 242
Lawrence 203
Jacksonville 188
Medford 178
Vienna 154
Nanjing 153
Pisa 151
Des Moines 126
Abidjan 95
Frankfurt am Main 82
Dong Ket 79
Redwood City 76
Hong Kong 75
Marseille 75
Dearborn 74
Nanchang 70
Florence 63
Rome 63
San Diego 60
Bern 50
Boulder 45
London 44
Shenyang 44
Brussels 41
Carrara 37
Nürnberg 37
Norwalk 36
Warsaw 36
Hebei 35
Dakar 34
Pescara 33
Bremen 30
Lagos 29
Kunming 25
Livorno 25
Pune 25
Washington 25
Auburn Hills 23
Changsha 23
Jüchen 23
Boardman 19
Hangzhou 19
Tianjin 18
Genoa 17
San Francisco 16
Middleton 15
Ogden 14
Orange 14
Lancaster 13
Chicago 12
Enterprise 12
Jiaxing 12
Lucca 12
Phoenix 12
Toronto 12
Jinan 11
Wuhan 11
Hefei 10
Eindhoven 9
Paris 9
San Giuliano Terme 9
Tokyo 9
Cascina 8
Dallas 8
Helsinki 8
Lacchiarella 8
Los Angeles 8
Indiana 7
Castel Focognano 6
Düsseldorf 6
Falls Church 6
Fremont 6
Guangzhou 6
Haikou 6
Morgantown 6
San Giuliano 6
Scafati 6
Sydney 6
Tappahannock 6
Changchun 5
Grosseto 5
Montignoso 5
Palermo 5
Shanghai 5
Totale 13.381
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Nome #
Design and synthesis of 2-oxindole based multi-targeted inhibitors of PDK1/Akt signaling pathway for the treatment of glioblastoma multiforme 209
Synthesis of Novel 3,5-Disubstituted-2-oxindole Derivatives As Antitumor Agents against Human Nonsmall Cell Lung Cancer 205
Iminothioethers as Hydrogen Sulfide Donors: From the Gasotransmitter Release to the Vascular Effects 175
Dual inhibition of PDK1 and Aurora Kinase A: an effective strategy to induce differentiation and apoptosis of human glioblastoma multiforme stem cells 162
A NEW NITRIC OXIDE RELEASING ANTI-DIABETIC HYBRID DRUG: FROM THE DESIGN TO THE PHARMACOLOGICAL CHARACTERIZATION 160
Combined inhibition of AKT/mTOR and MDM2 enhances Glioblastoma Multiforme cell apoptosis and differentiation of cancer stem cells 159
New NO-Releasing Pharmacodynamic Hybrids of Losartan and Its Active Metabolite: Design,Synthesis, and Biopharmacological Properties 158
Locking PDK1 in DFG-out conformation through 2-oxo-indole containing molecules: Another tools to fight glioblastoma 153
Arylthioamides as H2S Donors:l-Cysteine-Activated Releasing Properties and Vascular Effects in Vitro and in Vivo 148
Synthesis of Anthranylaldoxime Derivatives as Estrogen Receptor Ligands and Computational Prediction of Binding Modes 146
Salicylaldoximes and anthranylaldoximes as alternatives to phenol-based estrogen receptor ligands 141
Memantine prodrug as a new agent for alzheimer’s disease 140
Enantiopure 3-(arylmethylidene)aminoxy-2-methylpropionic acids: synthesis and antiinflammatory properties 139
A patent update on PDK1 inhibitors (2015-present) 138
Design, synthesis and pharmacological evaluation of novel tacrine-caffeic acid hybrids as multi-targeted compounds against Alzheimer's disease 137
Salicylaldoximes and anthranylaldoximes as alternatives to phenol-based estrogen receptor ligands 137
Synthesis and AT1 affinity evaluation of benzamidophenyl analogs of known AT1 receptor ligands with similar aromatic skeleton 137
Phosphonomethylphosphorylmethyl(oxy)-analogues of geranylgeranyl diphosphate as stable and selective geranylgeranyl protein transferase inhibitors 136
ANTI-ISCHEMIC PROPERTIES OF A NEW SPIRO-CYCLIC BENZOPYRAN ACTIVATOR OF CARDIAC MITOCHONDRIAL ATP-SENSITIVE POTASSIUM CHANNELS 134
null 132
2-[(3-Methoxyphenylethyl)phenoxy]-based ABCB1 inhibitors: effect of different basic side-chains on their biological properties 131
Mitochondrial Potassium Channels as Pharmacological Target for Cardioprotective Drugs 131
Tacrine-6-Ferulic Acid, a Novel Multifunctional Dimer Against Alzheimer's Disease, Prevents Oxidative Stress-Induced Neuronal Death Through Activating Nrf2/ARE/HO-1 Pathway in HT22 Cells 130
NO-Sartans: A New Class of Pharmacodynamic Hybrids as Cardiovascular Drugs 130
Anti-ischemic properties of a new spiro-cyclic benzopyran activator of the cardiac mito-KATP channel 128
Synthesis and evaluation of multi-functional NO-donor/insulin-secretagogue derivatives for the treatment of type II diabetes and its cardiovascular complications 128
Dimer of rivastigmine and caffeic acid or ferulic acid, preparation method and drug composition thereof 128
Antiarrhythmic activity of a new spiro-cyclic benzopyran activator of the cardiac mitochondrial ATP dependent potassium channels 128
2-OXO-1,2-DIHYDROPYRIDINE-3-CARBOXAMIDE COMPOUNDS AND THEIR USE AS INHIBITORS OF PDK1 (US Patent App. 15/735,468, 2018) 128
Synthesis and 5-HT2A, 5-HT1Aand a1-Binding Affinities of 2-[2- Hydroxy-3-(pyridin-3-yl-methyl)amino]-, 2-[2-Hydroxy-3-(2- pyridin-2-yl-ethyl)amino]- and 2-[2-Hydroxy-3-(4-N-methylpiperazin- 1-yl)-amino]propoxybenzaldehyde-O-(substituted) Benzyl Oximes 127
In-vitro evaluation of new pharmacodynamic hybrids with insulin secretagogue and NO-donor activity 127
Pharmacological study on the cardiovascular activity of no-sartans, pharmacodynamic hybridsexhibiting at1-antagonist and no-donor properties 126
New Insights into the Potential Roles of 3-Iodothyronamine (T1AM) and Newly Developed Thyronamine-Like TAAR1 Agonists in Neuroprotection 126
Synthesis of stable analogues of geranylgeranyl diphosphate possessing a (Z,E,E)-geranylgeranyl side chain, docking analysis, and biological assays for prenyl protein transferase inhibition 122
Novel adenosine 5'-triphosphate-sensitive potassium channel ligands: a patent overview (2005 - 2010) 121
Endogenous TH metabolite 3-iodothyronamine (T1AM) and synthetic thyronamine-like analogues SG-1 and SG-2 induce autophagy in human glioblastoma cells (U-87MG) 121
Ceramide analogues in apoptosis: a new strategy for anticancer drug development 120
Synthesis and functional evaluation of novel aldose reductase inhibitors bearing a spirobenzopyran scaffold 120
New Benzopyran-Based Openers of the Mitochondrial ATP-Sensitive Potassium Channel with Potent Anti-Ischemic Properties 119
A new development of matrix metalloproteinase inhibitors: twin hydroxamic acids as potent inhibitors of MMPs 117
New N-arylsulfonyl-N-alkoxyaminoacetohydroxamic acids as selective inhibitors of gelatinase A (MMP-2) 117
Spirocyclic Benzopyran-based derivatives as new anti-ischemic activators of mitochondrial ATP-sensitive potassium channel 116
Synthesis and In Vivo Imaging of N-(3-[11C]Methoxybenzyl)-2-(3-Methoxyphenyl)ethylaniline as a Potential Targeting Agent for P-glycoprotein 115
Diaryl-substituted salicyl- and anthranyl-ketoximes as potential estrogen receptor ligands 114
null 114
Synthesis of a Resveratrol Analogue with High Ceramide-Mediated Proapoptotic Activity on Human Breast Cancer Cells 113
SAR study on arylmethyloxyphenyl scaffold: Looking for a P-gp nanomolar affinity 113
Sulfonamido-derivatives of unsubstituted carbazoles as BACE1 inhibitors 113
Cardiac ATP-sensitive potassium channels, a potential target for an anti-ischaemic pharmacological strategy 112
Derivati arilpiperazinici quali inibitori della Glicoproteina-P (P-gp) utili nella Multidrug Resistance (MDR) indotta da chemioterapici 111
P-gp Transporter and its Role in Neurodegenerative Diseases 111
(E)-[2-(4-Methylsulphonylphenyl)-1-cyclopentenyl-1-methyliden]-(arylmethyloxy)amines. Methyleneaminoxymethyl (MAOM) analogues of diarylcyclopentenyl cyclooxygenase-2 inhibitors: synthesis and biological properties 111
2-OXO-1,2-DIHYDROPYRIDINE-3-CARBOXAMIDE COMPOUNDS AND THEIR USE AS DUAL INHIBITORS OF PDK1/AURA 111
Development of Classification Models for Identifying “True” P-glycoprotein (P-gp) Inhibitors Through Inhibition, ATPase Activation and Monolayer Efflux Assays 110
New spiromorpholone- and spiromorpholine-benzopyrane derivatives as potential activators of mito-KATP channel 109
H2S-RELEASING PROPERTIES OF NEW THIOAMIDE, IMINOTHIOETHER AND ISOTHIOCYANATE DERIVATIVES 109
Evaluation of the NO-releasing properties of NO-donor linkers 109
Nature-based molecules combined with rivastigmine: A symbiotic approach for the synthesis of new agents against Alzheimer's disease 109
Synthesis and prostaglandin synthase inhibitory activity of new aromatic O-alkyloxime ethers substituted with methylsulfonamido or methylsulfonyl groups on their aliphatic portion 107
Oxidative stress, mitochondrial abnormalities and proteins deposition: multitarget approaches in Alzheimer's disease 107
Variously substituted (phosphonoacetamido)oxy analogues of geranylgeranyl diphosphate (GGdP) as GGdP-transferase (GGTase) inhibitors and antiproliferative agents 105
Synthesis of aniline-type analogues of farnesyl diphosphate and their biological assays for prenyl protein transferase inhibitory activity 105
Synthesis, Antifungal Activity, and Molecular Modeling Studies of New Inverted Oxime Ethers of Oxiconazole 103
Epibatidine: A Promising Natural Alkaloid in Health 103
Aminobenzothiazoles as beta-Selective Estrogen Receptor Ligands 102
Synthesis and biological activities of vitamin D-like inhibitors of CYP24 hydroxylase 102
Design and synthesis of H2S-donor hybrids: A new treatment for Alzheimer's disease? 102
Conformationally restrained ceramide analogues: effects of lipophilic modifications on the antiproliferative activity 101
COMPOSTI 2-OXO-1,2-DIIDROPIRIDIN-3-CARBOSSAMMIDE E LORO USO COME INIBITORI DI PDK1. 101
NO-glibenclamide derivatives: prototypes of a new class of nitric oxide-releasing anti-diabetic drugs 101
THIOAMIDE, IMINOTHIOETHER AND ISOTHIOCYANATE DERIVATIVES: CHEMOTYPES OF SLOW H2S-RELEASING AGENTS 100
Dual PDK1/aurora kinase a inhibitors reduce pancreatic cancer cell proliferation and colony formation 100
Targeting the upregulated PI3K-PDK1-Akt pathway: a drug discovery approach of treating cancer. 99
Synthesis and Affinity Evaluation for AT1 Receptor of Phenylsalicylaldoxime-Derivatives Structurally Related to Sartans 99
alpha-Naphthylaminopropan-2-ol Derivatives as BACE1 Inhibitors 99
Hydrogen sulfide: A worthwhile tool in the design of new multitarget drugs 99
Discovery of novel N-substituted carbazoles as neuroprotective agents with potent anti-oxidative activity 98
Classification models for the identification of P-gp inhibitors 97
Synthesis and COX2 inhibitory properties of N-Phenyl-and N-benzyl-substituted amides of 2-(4-methylsulfonylphenyl)cyclopent-1-ene-1-carboxylic acid and of their pyrazole, thiophene, and isoxazole analogs 97
Aryl-substituted methyleneaminoxymethyl (MAOM) analogues of diarylcyclopentenyl cyclooxygenase-2 inhibitors: effects of some structural modifications on their biological properties 96
Synthesis and Biological Evaluation of (Hetero)Arylmethyloxy- and Arylmethylamine-phenyl Derivatives as Potent P-glycoprotein Modulating Agents 96
1-Phenylalkoxy-2-β-phenylethyl derivatives as P-glycoprotein (P-GP) inhibitors useful in drug resistance events 96
Synthesis of new potent P-glycoprotein inhibitors and their screening: potential tools to reduce the multidrug resistance 95
Novel Estrogen Receptor Ligands Based on an Anthranylaldoxime Structure: Role of the Phenol-Type Pseudocycle in the Binding Process 94
NO-Releasing Hybrids of Cardiovascular Drugs 93
Proposal of a new binding orientation for non-peptide AT1 antagonists: Homology modeling, docking and three-dimensional quantitative structure-activity relationship analysis 93
A Novel H2S-releasing Amino-Bisphosphonate which combines bone anti-catabolic and anabolic functions 93
NO-releasing hybrids of cardiovascular drugs 91
SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF NEW 7BETA-(BENZO[A]DIHYDROCARBAZOLYLOXYACETYL)-SUBSTITUTED CEPHALOSPORINS 91
Synthesis and Biological Evaluation of Cyclopropylamine Vitamin D‐Like CYP24A1 Inhibitors 91
Symbiotic approach applied to the synthesis of new agents for the treatment of Alzheimer’s disease 90
Classification models for the identification of P-gp inhibitors. 89
In-vitro evaluation of new pharmacodynamic hybrids with insulin secretagogue and NO-donor activity 87
Stable propylphosphonic acid analogues of geranylgeranyl diphosphate possessing inhibitory activity on geranylgeranyl protein transferase 87
Synthesis and pharmacological evaluation of multifunctional tacrine derivatives against several disease pathways of AD 87
A novel approach in glioblastoma multiforme drug discovery: Perturbation studies in vitro 87
Derivati 2,2-dimetilcromanici 4-spiro-eterociclici azotati (a 5 e 6 termini) N-sostituiti quali cardio-protettori nei confronti dell''insulto ischemico 86
Enantioselectivity in Cardioprotection induced by (S)- (-)-2,2-Dimethyl-N-(4'-acetamido-benzyl)-4-spiromorpholone-chromane 86
Synthesis and anti-glioblastoma effects of artemisinin-isothiocyanate derivatives 86
Sodium N-(Methylsulfonyl)-N-(4-nitro- 2-phenoxyphenyl)sulfamate: A Water-Soluble Nimesulide Prodrug for Parenteral Use 85
Totale 11.597
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Categoria #
all - tutte 44.626
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 44.626
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/20191.060 0 0 0 0 0 0 0 0 0 421 369 270
2019/20203.259 434 204 380 194 253 329 331 235 279 276 259 85
2020/20211.678 117 94 86 80 159 126 150 145 247 120 94 260
2021/20222.354 33 185 69 126 379 317 89 127 72 90 142 725
2022/20233.195 384 393 218 260 323 462 19 220 628 36 162 90
2023/20242.049 331 286 285 182 342 390 145 49 29 10 0 0
Totale 18.367