An effective Pd(II)/Ag(I)-promoted intramolecular crossdehydrogenative coupling (CDC) of substituted 1-benzylimidazoles under air provides for the first time a simple access to several functionalized imidazo[2,1-a]isoindoles, an interesting class of polycyclic heteroaromatic compounds. The direct involvement of two unactivated carbon-hydrogen bonds, without any directing group, grants an elevated atom economy of the whole process.

Imidazo-fused isoindoles by Pd(II)/Ag(I)-promoted intramolecular dehydrogenative coupling

Lessi, Marco
Primo
;
Cuzzola, Angela Rosa;Bellina, Fabio
Ultimo
2020-01-01

Abstract

An effective Pd(II)/Ag(I)-promoted intramolecular crossdehydrogenative coupling (CDC) of substituted 1-benzylimidazoles under air provides for the first time a simple access to several functionalized imidazo[2,1-a]isoindoles, an interesting class of polycyclic heteroaromatic compounds. The direct involvement of two unactivated carbon-hydrogen bonds, without any directing group, grants an elevated atom economy of the whole process.
2020
Lessi, Marco; Lucci, Antonio; Cuzzola, Angela Rosa; Bellina, Fabio
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11568/1033010
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