A greater decrease in 24-hour energy expenditure (24hEE) during short-term fasting is indicative of a thrifty phenotype. As ghrelin and the growth hormone (GH) - insulin-like growth factor 1 (IGF-1) axis are implicated in the regulation of energy intake and metabolism, we investigated whether ghrelin, GH and IGF-1 concentrations mediate the fasting-induced decrease in 24hEE that characterizes thriftiness.

Effects of Short-Term Fasting on Ghrelin/GH/IGF-1 Axis in Healthy Humans: the Role of Ghrelin in the Thrifty Phenotype

Basolo, Alessio;Piaggi, Paolo
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Abstract

A greater decrease in 24-hour energy expenditure (24hEE) during short-term fasting is indicative of a thrifty phenotype. As ghrelin and the growth hormone (GH) - insulin-like growth factor 1 (IGF-1) axis are implicated in the regulation of energy intake and metabolism, we investigated whether ghrelin, GH and IGF-1 concentrations mediate the fasting-induced decrease in 24hEE that characterizes thriftiness.
Hollstein, Tim; Basolo, Alessio; Unlu, Yigit; Ando, Takafumi; Walter, Mary; Krakoff, Jonathan; Piaggi, Paolo
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11568/1146380
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