MARZO, TIZIANO
 Distribuzione geografica
Continente #
NA - Nord America 4.458
EU - Europa 1.530
AS - Asia 1.099
AF - Africa 91
SA - Sud America 24
OC - Oceania 8
AN - Antartide 1
Totale 7.211
Nazione #
US - Stati Uniti d'America 4.405
IT - Italia 696
CN - Cina 560
SE - Svezia 268
SG - Singapore 267
BG - Bulgaria 172
VN - Vietnam 95
DE - Germania 73
CI - Costa d'Avorio 61
HK - Hong Kong 57
RU - Federazione Russa 54
CA - Canada 53
GB - Regno Unito 39
FI - Finlandia 36
IN - India 35
AT - Austria 34
EE - Estonia 33
TR - Turchia 31
FR - Francia 29
SN - Senegal 24
ES - Italia 20
BR - Brasile 18
BE - Belgio 14
JP - Giappone 13
GR - Grecia 12
NL - Olanda 12
CZ - Repubblica Ceca 11
PK - Pakistan 7
MY - Malesia 6
KR - Corea 5
PL - Polonia 5
UA - Ucraina 5
AU - Australia 4
IR - Iran 4
LT - Lituania 4
NZ - Nuova Zelanda 4
IE - Irlanda 3
IL - Israele 3
MO - Macao, regione amministrativa speciale della Cina 3
NG - Nigeria 3
RO - Romania 3
AE - Emirati Arabi Uniti 2
AR - Argentina 2
CH - Svizzera 2
IQ - Iraq 2
SA - Arabia Saudita 2
SK - Slovacchia (Repubblica Slovacca) 2
AM - Armenia 1
CO - Colombia 1
DZ - Algeria 1
GS - Georgia del Sud e Isole Sandwich Australi 1
ID - Indonesia 1
JO - Giordania 1
KW - Kuwait 1
LI - Liechtenstein 1
MA - Marocco 1
OM - Oman 1
PE - Perù 1
PT - Portogallo 1
QA - Qatar 1
RS - Serbia 1
TW - Taiwan 1
UY - Uruguay 1
VE - Venezuela 1
ZA - Sudafrica 1
Totale 7.211
Città #
Fairfield 539
Woodbridge 495
Santa Clara 431
Houston 349
Chandler 343
Ashburn 274
Seattle 251
Ann Arbor 239
Cambridge 213
Shanghai 205
Wilmington 181
Sofia 172
Serra 135
Singapore 129
Boardman 105
Beijing 100
New York 98
Pisa 95
Princeton 88
Lawrence 76
Abidjan 61
Milan 59
Medford 58
Hong Kong 56
Ottawa 48
Florence 47
Des Moines 44
Chicago 40
Bremen 34
Tallinn 33
Istanbul 31
Vienna 29
Nanjing 26
Dearborn 25
Boulder 24
Dakar 24
London 23
San Diego 22
Dong Ket 21
Fuzhou 19
Giussano 19
Ogden 19
Quanzhou 19
Livorno 17
Frankfurt am Main 16
Kent 16
Redwood City 15
Brussels 12
Dallas 12
Vicopisano 12
Lucca 11
Hebei 10
Phoenix 10
Bologna 9
Brno 9
Falls Church 9
Los Angeles 9
Helsinki 8
Hyderabad 8
Napoli 8
Norwalk 8
Wuhan 8
Hefei 7
Jiaxing 7
Kunming 7
Nanchang 7
Rome 7
Shenyang 7
Tokyo 7
Arezzo 6
Madrid 6
Pessac 6
Pune 6
Cascina 5
Changsha 5
Hangzhou 5
Jinan 5
Lappeenranta 5
Marseille 5
Prato 5
Washington 5
Chieti 4
Messina 4
Padova 4
Ponte San Pietro 4
San Giuliano Terme 4
Sesto Fiorentino 4
Siracusa 4
Wenzhou 4
Amherst 3
Barcelona 3
Burgos 3
Capannori 3
Caserta 3
Delhi 3
Gaeta 3
Massa 3
Pistoia 3
Quarrata 3
Tolentino 3
Totale 5.684
Nome #
Iridium(I) Compounds as Prospective Anticancer Agents: Solution Chemistry, Antiproliferative Profiles and Protein Interactions for a Series of Iridium(I) N-Heterocyclic Carbene Complexes 180
Chlorido and bromido oxaliplatin analogues as potential agents for CRC treatment: Solution behavior, protein binding and cytotoxicity evaluation 164
Interaction of gold N-heterocyclic carbenes with nucleic acids 153
PtI2(DACH), the Iodido Analogue of Oxaliplatin as a Candidate for Colorectal Cancer Treatment: Chemical and Biological Features 152
Auranofin and its Analogues Show Potent Antimicrobial Activity against Multidrug-Resistant Pathogens: Structure–Activity Relationships 148
Auranofin, Et3PAuCl, and Et3PAuI Are Highly Cytotoxic on Colorectal Cancer Cells: A Chemical and Biological Study 144
Photocytotoxic Pt(iv) complexes as prospective anticancer agents 143
Interactions of carboplatin and oxaliplatin with proteins: Insights from X-ray structures and mass spectrometry studies of their ribonuclease A adducts 142
Protein Metalation by Anticancer Metallodrugs: A Joint ESI MS and XRD Investigative Strategy 138
Gold(III) complexes with hydroxyquinoline, aminoquinoline and quinoline ligands: Synthesis, cytotoxicity, DNA and protein binding studies 136
cis-Pt I2(NH3)2: a reappraisal 133
Interaction of a Gold(I) Dicarbene Anticancer Drug with Human Telomeric DNA G-Quadruplex: Solution and Computationally Aided X-ray Diffraction Analysis 133
The combined activation of KCa3.1 and inhibition of Kv11.1/hERG1 currents contribute to overcome Cisplatin resistance in colorectal cancer cells 126
Cisplatin and its dibromido analogue: a comparison of chemical and biological profiles 121
Oxaliplatin vs. cisplatin: Competition experiments on their binding to lysozyme 121
Cytotoxic activity and protein binding through an unusual oxidative mechanism by an iridium(I)–NHC complex 116
Peculiar features in the crystal structure of the adduct formed between cis-PtI2(NH3)2 and hen egg white lysozyme. 115
The influence of oxo-bridged binuclear gold(III) complexes on Na/K-ATPase activity: a joint experimental and theoretical approach 111
Antiproliferative effects of two gold(I)-N-heterocyclic carbene complexes in A2780 human ovarian cancer cells: A comparative proteomic study 110
Two mixed valence diruthenium(ii,iii) isomeric complexes show different anticancer properties 108
null 107
Platinum(II) Complexes with O,S Bidentate Ligands: Biophysical Characterization, Antiproliferative Activity, and Crystallographic Evidence of Protein Binding 107
A first-in-class and a fished out anticancer platinum compound:: Cis -[PtCl2(NH3)2] and cis -[PtI2(NH3)2] compared for their reactivity towards DNA model systems 106
Interactions between Anticancertrans-Platinum Compounds and Proteins: Crystal Structures and ESI-MS Spectra of Two Protein Adducts of trans-(Dimethylamino)(methylamino)dichloridoplatinum(II) 105
Triethylphosphine gold iodide (I), the iodido analogue of Auranofin: comparative studies of a potential antineoplastic agent 103
Replacement of the Thiosugar of Auranofin with Iodide Enhances the Anticancer Potency in a Mouse Model of Ovarian Cancer 103
Reactions of model proteins with aurothiomalate, a clinically established gold(I) drug: The comparison with auranofin 101
Interaction of anticancer Ru(III) complexes with single stranded and duplex DNA model systems 100
The cisplatin/serum albumin system: A reappraisal 99
A case of extensive protein platination: The reaction of lysozyme with a Pt(ii)-terpyridine complex 95
Interplay of crystallography, Raman microspectroscopy and electrospray mass spectrometry for studying the reaction between ruthenium complexes and proteins 95
A Fluorescent Silver(I) Carbene Complex with Anticancer Properties: Synthesis, Characterization, and Biological Studies 95
Synthesis, DNA binding studies, and antiproliferative activity of novel Pt(II)-complexes with a L-alanyl-based ligand 94
A mixed-valence diruthenium(ii,iii) complex endowed with high stability: from experimental evidence to theoretical interpretation 94
Mechanistic studies on cytotoxic gold compounds 93
Synthesis and Mode of Action Studies on Iridium(I)–NHC Anticancer Drug Candidates 92
Arsenoplatin-1 Is a Dual Pharmacophore Anticancer Agent 92
ESI–MS studies of the reactions of novel platinum(II) complexes containing O,O′-chelated acetylacetonate and sulfur ligands with selected model proteins 91
The leading established metal-based drugs: a revisitation of their relevant physico-chemical data 90
Interactions of the organogold(III) compound Aubipyc with the copper chaperone Atox1: A joint mass spectrometry and circular dichroism investigation 89
Cytotoxic Ag(I) and Au(I) NHC-carbenes bind DNA and show TrxR inhibition 85
Reactions of Cytotoxic Metallodrugs with Lysozyme in pure DMSO explored through UV-Vis Absorption Spectroscopy and ESI MS 84
New platinum(II) and palladium(II) complexes with substituted terpyridine ligands: synthesis and characterization, cytotoxicity and reactivity towards biomolecules 82
Synthesis, characterization and DNA interactions of [Pt3(TPymT)Cl3], the trinuclear platinum(II) complex of the TPymT ligand 82
Elucidating the reactivity of Pt(II) complexes with (O,S) bidentate ligands towards DNA model systems 81
Neurotrophic Activity and Its Modulation by Zinc Ion of a Dimeric Peptide Mimicking the Brain-Derived Neurotrophic Factor N-Terminal Region 78
null 75
Reactions of a tetranuclear Pt-thiosemicarbazone complex with model proteins 75
Biological applications of thiocarbohydrazones and their metal complexes: A perspective review 75
Structural and solution chemistry, antiproliferative effects, and serum albumin binding of three pseudohalide derivatives of auranofin 75
On the Different Mode of Action of Au(I)/Ag(I)-NHC Bis-Anthracenyl Complexes Towards Selected Target Biomolecules 73
The first step of arsenoplatin-1 aggregation in solution unveiled by solving the crystal structure of its protein adduct 71
null 69
Mechanistic Insights Into the Anticancer Properties of the Auranofin Analog Au(PEt3)I: A Theoretical and Experimental Study 69
Strategies for the improvement of metal-based chemotherapeutic treatments 67
Anti-Staphylococcal Activity of the Auranofin Analogue Bearing Acetylcysteine in Place of the Thiosugar: An Experimental and Theoretical Investigation 67
Protein Metalation by Inorganic Anticancer Drugs 64
Metallo therapeutics for COVID-19. Exploiting metal-based compounds for the discovery of new antiviral drugs 63
Angiogenin and copper crossing in wound healing 63
Diruthenium Diacetate Catalysed Aerobic Oxidation of Hydroxylamines and Improved Chemoselectivity by Immobilisation to Lysozyme 62
Induction of a Four-Way Junction Structure in the DNA Palindromic Hexanucleotide 5′-d(CGTACG)-3′ by a Mononuclear Platinum Complex 59
Development of Effective Antibacterial Treatment: Lessons from the Past and Novel Approaches 58
Reaction with Proteins of a Five-Coordinate Platinum(II) Compound 57
Auranofin and its analogs as prospective agents for the treatment of colorectal cancer 57
Anticancer effects against colorectal cancer models of chloro(triethylphosphine)gold(I) encapsulated in PLGA–PEG nanoparticles 54
Reactions of cisplatin and cis-[PtI2(NH3)2] with molecular models of relevant protein sidechains: A comparative analysis 53
In vitro anti-sars-cov-2 activity of selected metal compounds and potential molecular basis for their actions based on computational study 52
null 52
Medicinal Hypervalent Tellurium Prodrugs Bearing Different Ligands: A Comparative Study of the Chemical Profiles of AS101 and Its Halido Replaced Analogues 51
Ruthenium(II) 1,4,7-trithiacyclononane complexes of curcumin and bisdemethoxycurcumin: Synthesis, characterization, and biological activity 51
AS101: An overview on a leading tellurium-based prodrug 50
Protein targets for anticancer metal based drugs 48
A complex bearing TSPO PIGA ligand coordinated to the [Au(PEt3)]+ pharmacophore is highly cytotoxic against ovarian cancer cells 46
A Role for Metal-Based Drugs in Fighting COVID-19 Infection? The Case of Auranofin 45
Reactions of Arsenoplatin-1 with Protein Targets: A Combined Experimental and Theoretical Study 42
The Effects on Angiogenesis of Relevant Inorganic Chemotherapeutics 41
Strike a balance: between metals and non-metals, metalloids as a source of anti-infective agents 41
null 41
Looking beyond dna as the target of inorganic chemotherapy agents: The key role of protein metalation and metal homeostasis 40
Drug repurposing meets DNA independent pathways: targeting alternative substrates for anticancer therapy 39
Peptides Derived from Angiogenin Regulate Cellular Copper Uptake 38
Cancer Immunotherapy: An Overview on Small Molecules as Inhibitors of the Immune Checkpoint PD-1/PD-L1 (2015-2021) 38
Reactivity of antitumor coinage metal-based N-heterocyclic carbene complexes with cysteine and selenocysteine protein sites 35
Inorganic Drugs as a Tool for Protein Structure Solving and Studies on Conformational Changes 34
Mechanistic Evaluations of the Effects of Auranofin Triethylphosphine Replacement with a Trimethylphosphite Moiety 34
A Graphene Oxide-Angiogenin Theranostic Nanoplatform for the Therapeutic Targeting of Angiogenic Processes: The Effect of Copper-Supplemented Medium 31
Diruthenium(ii,iii) paddlewheel complexes: effects of bridging and axial ligands on anticancer properties 30
Exploiting the Chemical Diversity of Metal Compounds as a Source of Novel Anti-COVID-19 Drugs 28
Cisplatin binding to angiogenin protein: new molecular pathways and targets for the drug's anticancer activity 28
Oxaliplatin(IV) Prodrugs Functionalized with Gemcitabine and Capecitabine Induce Blockage of Colorectal Cancer Cell Growth - An Investigation of the Activation Mechanism and Their Nanoformulation 26
Platinum-based Anticancer Drugs: Unveiling Novel Mechanisms of Action of Conventional Metallodrugs for Improved Therapies 24
Pd-Based Hybrid Nanoparticles As Multimodal Theranostic Nanomedicine 23
null 22
Description of a Non-Canonical AsPt Blue Species Originating from the Aerobic Oxidation of AP-1 in Aqueous Solution 22
Unusual Structural Features in the Lysozyme Derivative of the Tetrakis(acetato)chloridodiruthenium(II,III) Complex 22
An unprecedented palladium-arsenic catalytic cycle for nitriles hydration 21
The X-ray structure of the complex formed in the reaction between oxaliplatin and lysozyme 21
Dimolybdenum (II,II) paddlewheel complexes bearing non-steroidal anti-inflammatory drug ligands: Insights into the chemico-physical profile and first biological assessment 20
The binding of auranofin at DNA/RNA nucleobases: A DFT assessment 17
Tyrosine kinase inhibitors (TKIs) for ovarian cancer treatment: from organic to inorganic chemotherapeutics towards selectivity-a perspective overview 17
Totale 7.613
Categoria #
all - tutte 25.632
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 25.632


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020669 0 0 0 0 0 0 163 139 168 97 80 22
2020/2021802 59 28 65 52 30 44 30 58 179 65 63 129
2021/2022874 34 22 30 34 158 148 36 32 79 38 48 215
2022/20231.212 148 128 76 118 98 148 15 93 264 14 44 66
2023/2024909 42 60 69 33 119 125 140 57 22 24 74 144
2024/20251.197 21 117 15 236 308 355 145 0 0 0 0 0
Totale 7.672