SESTITO, SIMONA
 Distribuzione geografica
Continente #
NA - Nord America 1.961
EU - Europa 1.389
AS - Asia 270
AF - Africa 65
SA - Sud America 7
Continente sconosciuto - Info sul continente non disponibili 3
OC - Oceania 2
Totale 3.697
Nazione #
US - Stati Uniti d'America 1.926
IT - Italia 636
SE - Svezia 214
DE - Germania 195
CN - Cina 139
AT - Austria 84
BG - Bulgaria 82
FR - Francia 66
SG - Singapore 46
VN - Vietnam 46
CA - Canada 32
GB - Regno Unito 29
CI - Costa d'Avorio 26
SN - Senegal 21
RU - Federazione Russa 16
FI - Finlandia 14
BE - Belgio 11
HK - Hong Kong 11
CH - Svizzera 10
NG - Nigeria 10
NL - Olanda 10
IN - India 9
UA - Ucraina 8
TR - Turchia 7
BR - Brasile 5
EG - Egitto 5
PL - Polonia 5
UZ - Uzbekistan 4
ES - Italia 3
IR - Iran 3
AU - Australia 2
CL - Cile 2
CZ - Repubblica Ceca 2
EU - Europa 2
JP - Giappone 2
MX - Messico 2
SA - Arabia Saudita 2
ZA - Sudafrica 2
A1 - Anonimo 1
BA - Bosnia-Erzegovina 1
DK - Danimarca 1
DO - Repubblica Dominicana 1
ID - Indonesia 1
IE - Irlanda 1
MA - Marocco 1
RO - Romania 1
Totale 3.697
Città #
Fairfield 262
Woodbridge 234
Serra 225
Chandler 180
Houston 175
Milan 140
Ashburn 139
Seattle 126
Ann Arbor 119
Wilmington 87
Vienna 83
Sofia 82
Cambridge 76
Beijing 75
Princeton 51
New York 45
Frankfurt am Main 44
Lawrence 36
Pisa 36
Medford 29
Marseille 27
Abidjan 26
Ottawa 26
Des Moines 22
Dakar 21
Rome 19
Dong Ket 18
Florence 18
Boulder 16
Bremen 16
Carrara 16
Nanjing 16
Redwood City 12
San Diego 12
Brussels 11
Hong Kong 11
Livorno 11
Dearborn 10
Lagos 10
Eindhoven 8
London 7
Nanchang 7
Norwalk 7
Nürnberg 7
Bern 6
Genoa 5
Hebei 5
Lancaster 5
Pescara 5
Prato 5
San Francisco 5
San Giuliano Terme 5
Toronto 5
Warsaw 5
Wuhan 5
Paris 4
Phoenix 4
San Giuliano 4
Boardman 3
Changsha 3
Dallas 3
Genova 3
Ghazvin 3
Grosseto 3
Hangzhou 3
Izmir 3
Jacksonville 3
Lucca 3
Middleton 3
Pistoia 3
Singapore 3
Uppsala 3
Bhubaneswar 2
Cascina 2
Cetraro 2
Fremont 2
Gaeta 2
Giza 2
Indiana 2
Jinan 2
Kocaeli 2
Kunming 2
Leawood 2
Macomb 2
Migliarino Pisano 2
Montignoso 2
New Delhi 2
Ogden 2
Omegna 2
Palermo 2
Parma 2
San Jose 2
Scuola 2
Shenyang 2
Tashkent 2
Valdivia 2
Washington 2
Xi'an 2
Amsterdam 1
Auburn 1
Totale 2.762
Nome #
Design and synthesis of 2-oxindole based multi-targeted inhibitors of PDK1/Akt signaling pathway for the treatment of glioblastoma multiforme 209
Synthesis of Novel 3,5-Disubstituted-2-oxindole Derivatives As Antitumor Agents against Human Nonsmall Cell Lung Cancer 205
Dual inhibition of PDK1 and Aurora Kinase A: an effective strategy to induce differentiation and apoptosis of human glioblastoma multiforme stem cells 162
Combined inhibition of AKT/mTOR and MDM2 enhances Glioblastoma Multiforme cell apoptosis and differentiation of cancer stem cells 159
Locking PDK1 in DFG-out conformation through 2-oxo-indole containing molecules: Another tools to fight glioblastoma 153
Memantine prodrug as a new agent for alzheimer’s disease 140
A patent update on PDK1 inhibitors (2015-present) 137
null 132
2-OXO-1,2-DIHYDROPYRIDINE-3-CARBOXAMIDE COMPOUNDS AND THEIR USE AS INHIBITORS OF PDK1 (US Patent App. 15/735,468, 2018) 128
New Insights into the Potential Roles of 3-Iodothyronamine (T1AM) and Newly Developed Thyronamine-Like TAAR1 Agonists in Neuroprotection 126
Synthesis and functional evaluation of novel aldose reductase inhibitors bearing a spirobenzopyran scaffold 120
2-OXO-1,2-DIHYDROPYRIDINE-3-CARBOXAMIDE COMPOUNDS AND THEIR USE AS DUAL INHIBITORS OF PDK1/AURA 111
Nature-based molecules combined with rivastigmine: A symbiotic approach for the synthesis of new agents against Alzheimer's disease 109
Oxidative stress, mitochondrial abnormalities and proteins deposition: multitarget approaches in Alzheimer's disease 107
ACE2 in the era of SARS-CoV-2: controversies and novel perspectives 107
Epibatidine: A Promising Natural Alkaloid in Health 103
Design and synthesis of H2S-donor hybrids: A new treatment for Alzheimer's disease? 102
COMPOSTI 2-OXO-1,2-DIIDROPIRIDIN-3-CARBOSSAMMIDE E LORO USO COME INIBITORI DI PDK1. 101
Dual PDK1/aurora kinase a inhibitors reduce pancreatic cancer cell proliferation and colony formation 100
Targeting the upregulated PI3K-PDK1-Akt pathway: a drug discovery approach of treating cancer. 99
Hydrogen sulfide: A worthwhile tool in the design of new multitarget drugs 99
Synthesis and Biological Evaluation of Cyclopropylamine Vitamin D‐Like CYP24A1 Inhibitors 91
Symbiotic approach applied to the synthesis of new agents for the treatment of Alzheimer’s disease 90
Preclinical validation of 3-phosphoinositide-dependent protein kinase 1 inhibition in pancreatic cancer 84
Multi-targeted ChEI-copper chelating molecules as neuroprotective agents 84
COMPOSTI 2-OXO-1,2-DIIDROPIRIDIN-3-CARBOSSAMMIDE E LORO USO COME INIBITORI DUALI DI PDK1/AurA” 80
Areca catechu—From farm to food and biomedical applications 79
Design, synthesis and biological evaluation of novel TRβ selective agonists sustained by ADME-toxicity analysis 78
New Multitarget Approaches in the War Against Glioblastoma: A Mini-Perspective 69
null 68
Selective Thyroid Hormone Receptor-Beta (TRβ) Agonists: New Perspectives for the Treatment of Metabolic and Neurodegenerative Disorders 65
SUN-717 SG-2 a Novel Multi-Target Directed Ligand (MTDL) for the Treatment of Neurodegenerative Diseases (NDDS) 65
Design, Synthesis, and In Vitro Evaluation of Novel 8-Amino-Quinoline Combined with Natural Antioxidant Acids 59
H2S-BASED THERAPEUTIC AGENTS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES 47
Synthesis and pharmacological characterization of mitochondrial KATP channel openers with enhanced mitochondriotropic effects 43
A comprehensive assessment of a new series of 5′,6′-difluorobenzotriazole-acrylonitrile derivatives as microtubule targeting agents (MTAs) 37
Discovery of novel rivastigmine-hydroxycinnamic acid hybrids as multi-targeted agents for Alzheimer's disease 26
Hit-to-lead optimization of mouse Trace Amine Associated Receptor 1 (mTAAR1) agonists with a diphenylmethane-scaffold: Design, Synthesis, and biological study. 25
Design, synthesis, and biological screening of a series of 4'-fluoro-benzotriazole-acrylonitrile derivatives as microtubule-destabilising agents (MDAs) 24
Abstract 2569: Development of potent dual PDK1/AurA kinase inhibitors for Ewing sarcoma therapy 18
3-Iodothyronamine and Derivatives: New Allies Against Metabolic Syndrome? 13
Multi-Target Mechanisms of Phytochemicals in Alzheimer's Disease: Effects on Oxidative Stress, Neuroinflammation and Protein Aggregation 12
Totale 3.866
Categoria #
all - tutte 9.485
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 9.485


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/2019163 0 0 0 0 0 0 0 0 0 43 75 45
2019/2020804 82 42 90 60 60 79 71 69 80 97 58 16
2020/2021520 26 34 54 38 21 30 25 47 93 61 32 59
2021/2022395 5 11 20 23 65 52 22 21 18 9 19 130
2022/2023836 95 109 68 62 85 116 6 38 190 15 30 22
2023/2024445 85 58 83 49 65 54 32 13 5 1 0 0
Totale 3.866