SESTITO, SIMONA
 Distribuzione geografica
Continente #
NA - Nord America 2.277
EU - Europa 1.472
AS - Asia 667
AF - Africa 66
SA - Sud America 51
Continente sconosciuto - Info sul continente non disponibili 3
OC - Oceania 2
Totale 4.538
Nazione #
US - Stati Uniti d'America 2.236
IT - Italia 640
CN - Cina 307
SE - Svezia 210
DE - Germania 207
SG - Singapore 187
AT - Austria 88
BG - Bulgaria 80
FR - Francia 70
HK - Hong Kong 69
GB - Regno Unito 50
VN - Vietnam 46
BR - Brasile 45
RU - Federazione Russa 44
CA - Canada 35
CI - Costa d'Avorio 25
TR - Turchia 23
SN - Senegal 21
FI - Finlandia 16
IN - India 14
NL - Olanda 14
CH - Svizzera 10
NG - Nigeria 10
BE - Belgio 8
UA - Ucraina 8
PL - Polonia 6
CZ - Repubblica Ceca 5
LT - Lituania 5
EG - Egitto 4
UZ - Uzbekistan 4
ES - Italia 3
IR - Iran 3
MX - Messico 3
PE - Perù 3
ZA - Sudafrica 3
AU - Australia 2
BD - Bangladesh 2
CL - Cile 2
EU - Europa 2
IQ - Iraq 2
JP - Giappone 2
SA - Arabia Saudita 2
A1 - Anonimo 1
AE - Emirati Arabi Uniti 1
AL - Albania 1
AZ - Azerbaigian 1
BA - Bosnia-Erzegovina 1
BJ - Benin 1
DK - Danimarca 1
DO - Repubblica Dominicana 1
EC - Ecuador 1
EE - Estonia 1
GE - Georgia 1
ID - Indonesia 1
IE - Irlanda 1
IM - Isola di Man 1
JM - Giamaica 1
LV - Lettonia 1
MA - Marocco 1
NP - Nepal 1
PA - Panama 1
PH - Filippine 1
RO - Romania 1
TG - Togo 1
Totale 4.538
Città #
Fairfield 259
Woodbridge 234
Serra 221
Chandler 176
Houston 175
Santa Clara 149
Ashburn 143
Milan 142
Seattle 125
Ann Arbor 114
Shanghai 99
Vienna 86
Wilmington 85
Sofia 80
Cambridge 76
Beijing 75
Singapore 70
Hong Kong 69
Boardman 60
Princeton 50
Frankfurt am Main 45
New York 45
Chicago 38
Lawrence 35
Pisa 33
Medford 29
Rome 28
Marseille 26
Ottawa 26
Abidjan 25
Des Moines 22
Fort Wayne 22
Dakar 21
London 20
Florence 19
Dong Ket 18
Boulder 16
Bremen 16
Istanbul 16
Nanjing 16
Carrara 13
Dallas 13
Fuzhou 12
Redwood City 12
Nuremberg 11
Ogden 11
San Diego 11
Dearborn 10
Lagos 10
Brussels 8
Eindhoven 8
Livorno 8
Toronto 8
Nanchang 7
Nürnberg 7
Wuhan 7
Bern 6
Norwalk 6
Warsaw 6
Genoa 5
Hangzhou 5
Hebei 5
Lancaster 5
Los Angeles 5
Pescara 5
Prato 5
Quanzhou 5
San Francisco 5
San Giuliano Terme 5
Council Bluffs 4
Hyderabad 4
Paris 4
Pessac 4
Phoenix 4
Rio de Janeiro 4
San Giuliano 4
Changsha 3
Genova 3
Ghazvin 3
Grosseto 3
Helsinki 3
Izmir 3
Jacksonville 3
Lucca 3
Middleton 3
Pistoia 3
San Jose 3
Siena 3
Uberaba 3
Uppsala 3
Amsterdam 2
Bhubaneswar 2
Brno 2
Cascina 2
Cetraro 2
Chaohu 2
Easley 2
Falkenstein 2
Fremont 2
Gaeta 2
Totale 3.318
Nome #
Synthesis of Novel 3,5-Disubstituted-2-oxindole Derivatives As Antitumor Agents against Human Nonsmall Cell Lung Cancer 235
Design and synthesis of 2-oxindole based multi-targeted inhibitors of PDK1/Akt signaling pathway for the treatment of glioblastoma multiforme 231
A patent update on PDK1 inhibitors (2015-present) 197
2-OXO-1,2-DIHYDROPYRIDINE-3-CARBOXAMIDE COMPOUNDS AND THEIR USE AS INHIBITORS OF PDK1 (US Patent App. 15/735,468, 2018) 188
Locking PDK1 in DFG-out conformation through 2-oxo-indole containing molecules: Another tools to fight glioblastoma 180
Dual inhibition of PDK1 and Aurora Kinase A: an effective strategy to induce differentiation and apoptosis of human glioblastoma multiforme stem cells 180
Combined inhibition of AKT/mTOR and MDM2 enhances Glioblastoma Multiforme cell apoptosis and differentiation of cancer stem cells 177
2-OXO-1,2-DIHYDROPYRIDINE-3-CARBOXAMIDE COMPOUNDS AND THEIR USE AS DUAL INHIBITORS OF PDK1/AURA 171
Memantine prodrug as a new agent for alzheimer’s disease 158
New Insights into the Potential Roles of 3-Iodothyronamine (T1AM) and Newly Developed Thyronamine-Like TAAR1 Agonists in Neuroprotection 145
Synthesis and functional evaluation of novel aldose reductase inhibitors bearing a spirobenzopyran scaffold 140
null 132
Nature-based molecules combined with rivastigmine: A symbiotic approach for the synthesis of new agents against Alzheimer's disease 130
ACE2 in the era of SARS-CoV-2: controversies and novel perspectives 129
Oxidative stress, mitochondrial abnormalities and proteins deposition: multitarget approaches in Alzheimer's disease 128
Targeting the upregulated PI3K-PDK1-Akt pathway: a drug discovery approach of treating cancer. 125
Design and synthesis of H2S-donor hybrids: A new treatment for Alzheimer's disease? 122
Epibatidine: A Promising Natural Alkaloid in Health 120
Hydrogen sulfide: A worthwhile tool in the design of new multitarget drugs 119
Dual PDK1/aurora kinase a inhibitors reduce pancreatic cancer cell proliferation and colony formation 116
Symbiotic approach applied to the synthesis of new agents for the treatment of Alzheimer’s disease 113
COMPOSTI 2-OXO-1,2-DIIDROPIRIDIN-3-CARBOSSAMMIDE E LORO USO COME INIBITORI DI PDK1. 112
Synthesis and Biological Evaluation of Cyclopropylamine Vitamin D‐Like CYP24A1 Inhibitors 112
Multi-targeted ChEI-copper chelating molecules as neuroprotective agents 108
Preclinical validation of 3-phosphoinositide-dependent protein kinase 1 inhibition in pancreatic cancer 100
Design, synthesis and biological evaluation of novel TRβ selective agonists sustained by ADME-toxicity analysis 100
Areca catechu—From farm to food and biomedical applications 98
COMPOSTI 2-OXO-1,2-DIIDROPIRIDIN-3-CARBOSSAMMIDE E LORO USO COME INIBITORI DUALI DI PDK1/AurA” 90
New Multitarget Approaches in the War Against Glioblastoma: A Mini-Perspective 87
Design, Synthesis, and In Vitro Evaluation of Novel 8-Amino-Quinoline Combined with Natural Antioxidant Acids 87
SUN-717 SG-2 a Novel Multi-Target Directed Ligand (MTDL) for the Treatment of Neurodegenerative Diseases (NDDS) 84
null 68
H2S-BASED THERAPEUTIC AGENTS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES 61
Synthesis and pharmacological characterization of mitochondrial KATP channel openers with enhanced mitochondriotropic effects 60
A comprehensive assessment of a new series of 5′,6′-difluorobenzotriazole-acrylonitrile derivatives as microtubule targeting agents (MTAs) 60
Discovery of novel rivastigmine-hydroxycinnamic acid hybrids as multi-targeted agents for Alzheimer's disease 55
Hit-to-lead optimization of mouse Trace Amine Associated Receptor 1 (mTAAR1) agonists with a diphenylmethane-scaffold: Design, Synthesis, and biological study. 50
Design, synthesis, and biological screening of a series of 4'-fluoro-benzotriazole-acrylonitrile derivatives as microtubule-destabilising agents (MDAs) 40
Abstract 2569: Development of potent dual PDK1/AurA kinase inhibitors for Ewing sarcoma therapy 39
3-Iodothyronamine and Derivatives: New Allies Against Metabolic Syndrome? 29
Multi-Target Mechanisms of Phytochemicals in Alzheimer's Disease: Effects on Oxidative Stress, Neuroinflammation and Protein Aggregation 28
Discovery of pyridoquinoxaline-based new P-gp inhibitors as coadjutant against Multi Drug Resistance in cancer 7
Totale 4.711
Categoria #
all - tutte 13.729
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 13.729


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020251 0 0 0 0 0 0 0 0 80 97 58 16
2020/2021498 26 34 47 38 21 29 25 44 90 59 27 58
2021/2022385 5 11 19 23 63 50 22 21 16 9 18 128
2022/2023814 94 108 66 62 83 113 5 35 185 15 29 19
2023/2024557 83 58 82 45 62 54 32 12 5 16 23 85
2024/2025787 17 57 37 89 126 135 103 71 152 0 0 0
Totale 4.711