SESTITO, SIMONA
 Distribuzione geografica
Continente #
NA - Nord America 3.435
EU - Europa 1.767
AS - Asia 1.650
SA - Sud America 227
AF - Africa 98
OC - Oceania 4
Continente sconosciuto - Info sul continente non disponibili 3
Totale 7.184
Nazione #
US - Stati Uniti d'America 3.352
IT - Italia 695
CN - Cina 489
SG - Singapore 484
HK - Hong Kong 269
DE - Germania 242
SE - Svezia 219
BR - Brasile 175
VN - Vietnam 164
FR - Francia 121
AT - Austria 90
BG - Bulgaria 81
GB - Regno Unito 77
FI - Finlandia 53
CA - Canada 52
RU - Federazione Russa 52
IN - India 40
TR - Turchia 34
NL - Olanda 33
JP - Giappone 31
BD - Bangladesh 27
CI - Costa d'Avorio 25
PL - Polonia 25
SN - Senegal 23
CH - Svizzera 21
IQ - Iraq 21
MX - Messico 17
AR - Argentina 15
KR - Corea 14
ZA - Sudafrica 14
UA - Ucraina 12
NG - Nigeria 11
ID - Indonesia 10
UZ - Uzbekistan 10
BE - Belgio 9
EC - Ecuador 9
LT - Lituania 9
SA - Arabia Saudita 9
ES - Italia 8
MA - Marocco 8
CL - Cile 7
PK - Pakistan 7
CO - Colombia 6
IL - Israele 6
PH - Filippine 6
CZ - Repubblica Ceca 5
EG - Egitto 5
VE - Venezuela 5
MY - Malesia 4
UY - Uruguay 4
AU - Australia 3
AZ - Azerbaigian 3
IR - Iran 3
PE - Perù 3
PY - Paraguay 3
RO - Romania 3
TN - Tunisia 3
TW - Taiwan 3
AE - Emirati Arabi Uniti 2
BJ - Benin 2
EU - Europa 2
GT - Guatemala 2
HN - Honduras 2
JM - Giamaica 2
JO - Giordania 2
KE - Kenya 2
KH - Cambogia 2
KW - Kuwait 2
PA - Panama 2
PS - Palestinian Territory 2
PT - Portogallo 2
A1 - Anonimo 1
AL - Albania 1
AO - Angola 1
BA - Bosnia-Erzegovina 1
BB - Barbados 1
CD - Congo 1
CR - Costa Rica 1
DK - Danimarca 1
DO - Repubblica Dominicana 1
EE - Estonia 1
GE - Georgia 1
IE - Irlanda 1
IM - Isola di Man 1
KG - Kirghizistan 1
KZ - Kazakistan 1
LU - Lussemburgo 1
LV - Lettonia 1
MD - Moldavia 1
MG - Madagascar 1
NI - Nicaragua 1
NO - Norvegia 1
NP - Nepal 1
NZ - Nuova Zelanda 1
SY - Repubblica araba siriana 1
TG - Togo 1
TH - Thailandia 1
TT - Trinidad e Tobago 1
UG - Uganda 1
VG - Isole Vergini Britanniche 1
Totale 7.184
Città #
Ashburn 397
Hong Kong 266
Singapore 264
Fairfield 259
Woodbridge 234
San Jose 226
Serra 221
Dallas 190
Houston 181
Chandler 176
Santa Clara 157
Milan 146
Seattle 126
Ann Arbor 114
Beijing 112
Shanghai 101
Vienna 86
Wilmington 85
Sofia 81
Boardman 77
Cambridge 76
New York 64
Frankfurt am Main 58
Chicago 56
Council Bluffs 54
Los Angeles 51
Princeton 50
Rome 37
Pisa 36
Helsinki 35
Lawrence 35
Ho Chi Minh City 33
Hanoi 30
Hefei 30
Medford 29
Lauterbourg 28
Fort Wayne 26
Marseille 26
Ottawa 26
Abidjan 25
London 25
Tokyo 25
Dakar 23
Des Moines 23
Florence 23
Warsaw 21
Orem 20
Dong Ket 18
Istanbul 17
Boulder 16
Bremen 16
Nanjing 16
Tianjin 16
Buffalo 15
Redondo Beach 15
Carrara 13
Munich 13
Nuremberg 13
Seoul 13
Fuzhou 12
Redwood City 12
San Francisco 12
Zurich 12
Groningen 11
Lagos 11
Ogden 11
San Diego 11
Dearborn 10
Phoenix 10
The Dalles 10
Toronto 10
Boston 9
Paris 9
São Paulo 9
Amsterdam 8
Baghdad 8
Brussels 8
Da Nang 8
Düsseldorf 8
Eindhoven 8
Johannesburg 8
Livorno 8
Montreal 8
Rio de Janeiro 8
Tucson 8
Brooklyn 7
Denver 7
Haiphong 7
Nanchang 7
Nürnberg 7
Tashkent 7
Wuhan 7
Xi'an 7
Atlanta 6
Bern 6
Changsha 6
Chennai 6
Hangzhou 6
Memphis 6
North Charleston 6
Totale 4.990
Nome #
2-OXO-1,2-DIHYDROPYRIDINE-3-CARBOXAMIDE COMPOUNDS AND THEIR USE AS INHIBITORS OF PDK1 (US Patent App. 15/735,468, 2018) 312
Design and synthesis of 2-oxindole based multi-targeted inhibitors of PDK1/Akt signaling pathway for the treatment of glioblastoma multiforme 303
2-OXO-1,2-DIHYDROPYRIDINE-3-CARBOXAMIDE COMPOUNDS AND THEIR USE AS DUAL INHIBITORS OF PDK1/AURA 300
Synthesis of Novel 3,5-Disubstituted-2-oxindole Derivatives As Antitumor Agents against Human Nonsmall Cell Lung Cancer 293
A patent update on PDK1 inhibitors (2015-present) 280
Nature-based molecules combined with rivastigmine: A symbiotic approach for the synthesis of new agents against Alzheimer's disease 252
Locking PDK1 in DFG-out conformation through 2-oxo-indole containing molecules: Another tools to fight glioblastoma 235
Dual inhibition of PDK1 and Aurora Kinase A: an effective strategy to induce differentiation and apoptosis of human glioblastoma multiforme stem cells 231
Combined inhibition of AKT/mTOR and MDM2 enhances Glioblastoma Multiforme cell apoptosis and differentiation of cancer stem cells 229
Memantine prodrug as a new agent for alzheimer’s disease 225
Design and synthesis of H2S-donor hybrids: A new treatment for Alzheimer's disease? 199
Oxidative stress, mitochondrial abnormalities and proteins deposition: multitarget approaches in Alzheimer's disease 198
Epibatidine: A Promising Natural Alkaloid in Health 198
ACE2 in the era of SARS-CoV-2: controversies and novel perspectives 196
Design, Synthesis, and In Vitro Evaluation of Novel 8-Amino-Quinoline Combined with Natural Antioxidant Acids 195
Synthesis and functional evaluation of novel aldose reductase inhibitors bearing a spirobenzopyran scaffold 189
New Insights into the Potential Roles of 3-Iodothyronamine (T1AM) and Newly Developed Thyronamine-Like TAAR1 Agonists in Neuroprotection 189
Dual PDK1/aurora kinase a inhibitors reduce pancreatic cancer cell proliferation and colony formation 184
Targeting the upregulated PI3K-PDK1-Akt pathway: a drug discovery approach of treating cancer. 172
Design, synthesis and biological evaluation of novel TRβ selective agonists sustained by ADME-toxicity analysis 166
Hydrogen sulfide: A worthwhile tool in the design of new multitarget drugs 165
Preclinical validation of 3-phosphoinositide-dependent protein kinase 1 inhibition in pancreatic cancer 162
Symbiotic approach applied to the synthesis of new agents for the treatment of Alzheimer’s disease 161
Areca catechu—From farm to food and biomedical applications 157
Discovery of pyridoquinoxaline-based new P-gp inhibitors as coadjutant against Multi Drug Resistance in cancer 153
Synthesis and Biological Evaluation of Cyclopropylamine Vitamin D‐Like CYP24A1 Inhibitors 153
Multi-targeted ChEI-copper chelating molecules as neuroprotective agents 150
New Multitarget Approaches in the War Against Glioblastoma: A Mini-Perspective 147
SUN-717 SG-2 a Novel Multi-Target Directed Ligand (MTDL) for the Treatment of Neurodegenerative Diseases (NDDS) 145
COMPOSTI 2-OXO-1,2-DIIDROPIRIDIN-3-CARBOSSAMMIDE E LORO USO COME INIBITORI DI PDK1. 138
null 132
COMPOSTI 2-OXO-1,2-DIIDROPIRIDIN-3-CARBOSSAMMIDE E LORO USO COME INIBITORI DUALI DI PDK1/AurA” 122
Hit-to-lead optimization of mouse Trace Amine Associated Receptor 1 (mTAAR1) agonists with a diphenylmethane-scaffold: Design, Synthesis, and biological study. 117
Discovery of novel rivastigmine-hydroxycinnamic acid hybrids as multi-targeted agents for Alzheimer's disease 113
Synthesis and pharmacological characterization of mitochondrial KATP channel openers with enhanced mitochondriotropic effects 110
A comprehensive assessment of a new series of 5′,6′-difluorobenzotriazole-acrylonitrile derivatives as microtubule targeting agents (MTAs) 105
H2S-BASED THERAPEUTIC AGENTS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES 104
Design, synthesis, and biological screening of a series of 4'-fluoro-benzotriazole-acrylonitrile derivatives as microtubule-destabilising agents (MDAs) 98
Abstract 2569: Development of potent dual PDK1/AurA kinase inhibitors for Ewing sarcoma therapy 97
3-Iodothyronamine and Derivatives: New Allies Against Metabolic Syndrome? 80
Multi-Target Mechanisms of Phytochemicals in Alzheimer's Disease: Effects on Oxidative Stress, Neuroinflammation and Protein Aggregation 75
null 68
Design, synthesis and biological evaluation of new H2S-releasing rivastigmine derivatives as neuroprotective molecules 57
Efficacy of memantine prodrug microemulsion in a Preclinical model of tendinopathy 8
Totale 7.363
Categoria #
all - tutte 20.165
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 20.165


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/202158 0 0 0 0 0 0 0 0 0 0 0 58
2021/2022385 5 11 19 23 63 50 22 21 16 9 18 128
2022/2023814 94 108 66 62 83 113 5 35 185 15 29 19
2023/2024557 83 58 82 45 62 54 32 12 5 16 23 85
2024/20251.382 17 57 37 89 126 135 103 71 161 160 153 273
2025/20262.057 150 234 186 194 270 153 290 103 142 169 124 42
Totale 7.363