GIACOMELLI, CHIARA
 Distribuzione geografica
Continente #
NA - Nord America 6.712
EU - Europa 3.884
AS - Asia 3.360
SA - Sud America 501
AF - Africa 212
OC - Oceania 27
Continente sconosciuto - Info sul continente non disponibili 3
Totale 14.699
Nazione #
US - Stati Uniti d'America 6.441
IT - Italia 1.983
SG - Singapore 1.087
CN - Cina 1.061
HK - Hong Kong 505
BR - Brasile 439
DE - Germania 387
SE - Svezia 383
CA - Canada 210
VN - Vietnam 197
BG - Bulgaria 192
GB - Regno Unito 153
FR - Francia 141
AT - Austria 135
RU - Federazione Russa 122
TR - Turchia 96
FI - Finlandia 87
IN - India 86
KR - Corea 68
UA - Ucraina 62
JP - Giappone 53
SN - Senegal 51
NG - Nigeria 48
NL - Olanda 45
PL - Polonia 40
EE - Estonia 38
CI - Costa d'Avorio 34
MX - Messico 30
IQ - Iraq 29
AU - Australia 26
PK - Pakistan 25
BE - Belgio 24
ZA - Sudafrica 23
ES - Italia 22
ID - Indonesia 22
BD - Bangladesh 20
EG - Egitto 19
AR - Argentina 16
MA - Marocco 14
UZ - Uzbekistan 14
CH - Svizzera 13
SA - Arabia Saudita 12
EC - Ecuador 11
IR - Iran 10
LT - Lituania 10
AZ - Azerbaigian 9
CZ - Repubblica Ceca 9
JO - Giordania 9
KE - Kenya 9
CO - Colombia 8
JM - Giamaica 8
MY - Malesia 8
AE - Emirati Arabi Uniti 6
CL - Cile 6
RS - Serbia 6
VE - Venezuela 6
GR - Grecia 5
IL - Israele 5
PA - Panama 5
PH - Filippine 5
PT - Portogallo 5
RO - Romania 5
CR - Costa Rica 4
KG - Kirghizistan 4
NP - Nepal 4
PE - Perù 4
TN - Tunisia 4
TT - Trinidad e Tobago 4
TW - Taiwan 4
UY - Uruguay 4
AL - Albania 3
BH - Bahrain 3
ET - Etiopia 3
HR - Croazia 3
IE - Irlanda 3
SK - Slovacchia (Repubblica Slovacca) 3
A1 - Anonimo 2
BA - Bosnia-Erzegovina 2
BO - Bolivia 2
DO - Repubblica Dominicana 2
GE - Georgia 2
GT - Guatemala 2
GY - Guiana 2
HN - Honduras 2
KW - Kuwait 2
KZ - Kazakistan 2
LB - Libano 2
NI - Nicaragua 2
OM - Oman 2
PS - Palestinian Territory 2
PY - Paraguay 2
QA - Qatar 2
AM - Armenia 1
AO - Angola 1
BB - Barbados 1
BF - Burkina Faso 1
BJ - Benin 1
BN - Brunei Darussalam 1
DZ - Algeria 1
GA - Gabon 1
Totale 14.688
Città #
Serra 742
Ashburn 689
Dallas 617
Woodbridge 545
Singapore 532
Ann Arbor 497
Hong Kong 496
Fairfield 466
Santa Clara 397
Houston 371
Chandler 351
Beijing 239
Shanghai 225
Seattle 196
Sofia 192
New York 168
Milan 162
Wilmington 160
Ottawa 159
Los Angeles 153
Boardman 145
Cambridge 142
Pisa 125
Vienna 118
Princeton 111
Hefei 85
Florence 75
Lawrence 73
Medford 71
Frankfurt am Main 65
Des Moines 62
London 53
Munich 52
Dakar 51
Lucca 51
Nanjing 49
Seoul 49
Lagos 45
Rho 44
Livorno 43
Bremen 42
Tokyo 42
Dong Ket 41
Ho Chi Minh City 41
Redondo Beach 40
Tallinn 38
Buffalo 36
São Paulo 35
Abidjan 34
Guangzhou 34
Istanbul 34
Dearborn 33
Alessandria 32
Chicago 32
Rome 31
Redwood City 29
Warsaw 29
Boulder 28
Turku 26
Council Bluffs 25
Brussels 23
Hanoi 23
Kent 21
Ogden 21
Pistoia 21
Nuremberg 20
Nanchang 18
Toronto 17
Jacksonville 16
Kunming 16
Phoenix 16
Rio de Janeiro 16
San Giuliano Terme 16
Amsterdam 14
Montreal 14
Orem 14
Paris 14
Chennai 13
Fuzhou 13
San Diego 13
Sydney 13
Washington 13
Columbus 12
Denver 12
Düsseldorf 12
Johannesburg 12
Marseille 12
Naples 12
Tashkent 12
Atlanta 11
Belo Horizonte 11
Izmir 11
The Dalles 11
Cascina 10
Falls Church 10
Helsinki 10
Konya 10
Nürnberg 10
Pessac 10
Shenyang 10
Totale 10.111
Nome #
TSPO ligand residence time influences human glioblastoma multiforme cell death/life balance 319
Apoptosis Therapy in Cancer: The First Single-molecule Co-activating p53 and the Translocator Protein in Glioblastoma 260
α-Synuclein Aggregated with Tau and β-Amyloid in Human Platelets from Healthy Subjects: Correlation with Physical Exercise 245
Phytochemical analysis and antisenescence activity of Sorbus torminalis (L.) Crantz and Elaeagnus umbellata Thunb fruits 240
G PROTEIN-COUPLED RECEPTOR DESENSITISATION REGULATES STEM CELL DIFFERENTIATION 233
Bax Activation Blocks Self-Renewal and Induces Apoptosis of Human Glioblastoma Stem Cells 233
New insights into the anticancer activity of carnosol: P53 reactivation in the U87MG human glioblastoma cell line 228
Osteogenesis Is Improved by Low Tumor Necrosis Factor Alpha Concentration through the Modulation of Gs-Coupled Receptor Signals 222
Allosteric modulators of human A2B adenosine receptor. 221
Deepening the Topology of the Translocator Protein Binding Site by Novel N,N-Dialkyl-2-arylindol-3-ylglyoxylamides 219
TSPO PIGA ligands promote neurosteroidogenesis and human astrocyte well-being 211
α-Synuclein Heterocomplexes with β-Amyloid Are Increased in Red Blood Cells of Parkinson's Disease Patients and Correlate with Disease Severity 209
Dual inhibition of PDK1 and Aurora Kinase A: an effective strategy to induce differentiation and apoptosis of human glioblastoma multiforme stem cells 207
p53 Functional Inhibitors Behaving Like Pifithrin-β Counteract the Alzheimer Peptide Non-β-amyloid Component Effects in Human SH-SY5Y Cells. 205
Bifunctional Inhibitors as a New Tool To Reduce Cancer Cell Invasion by Impairing MMP-9 Homodimerization 205
Force induces axon growth in inhibitory conditions 202
Carnosol controls the human glioblastoma stemness features through the epithelial-mesenchymal transition modulation and the induction of cancer stem cell apoptosis 201
Effect of Ribes nigrum bud extract on human gingival mesenchymal stem cell cytokine release: a role on regenerative processes 200
TSPO ligand residence time: a new parameter to predict compound neurosteroidogenic efficacy 198
Long lasting inhibition of Mdm2-p53 interaction potentiates mesenchymal stem cell differentiation into osteoblasts 197
Lactate dehydrogenase-A inhibition induces human glioblastoma multiforme stem cell differentiation and death 195
Discovery of N-Hydroxyindole-Based Inhibitors of Human Lactate Dehydrogenase Isoform a (LDH-A) as Starvation Agents against Cancer Cells 187
Drug-target Residence Time: a key parameter in glial responses to TSPO ligands 184
Neurotrophic Activity and Its Modulation by Zinc Ion of a Dimeric Peptide Mimicking the Brain-Derived Neurotrophic Factor N-Terminal Region 183
Epigenetic Modifications of the α-Synuclein Gene and Relative Protein Content Are Affected by Ageing and Physical Exercise in Blood from Healthy Subjects 183
Osteoblast differentiation and survival: A role for A2B adenosine receptor allosteric modulators. 182
Negative effects of a high tumour necrosis factor-α concentration on human gingival mesenchymal stem cell trophism: The use of natural compounds as modulatory agents 177
Apolipoprotein E ε4 triggers neurotoxicity via cholesterol accumulation, acetylcholine dyshomeostasis, and PKCε mislocalization in cholinergic neuronal cells 175
Further studies on pyrazolo[1',5':1,6]pyrimido[4,5-d]pyridazin-4(3H)-ones as potent and selective human A1 adenosine receptor antagonists. 175
The A2B adenosine receptor modulates the epithelial- mesenchymal transition through the balance of cAMP/PKA and MAPK/ERK pathway activation in human epithelial lung cells 175
Modulation of A2B Adenosine Receptor by 1-Benzyl-3-ketoindole Derivatives 173
Targeting the 18-kDa translocator protein: Recent perspectives for neuroprotection 172
Antioxidant activity of compounds isolated from Elaeagnus umbellata promotes human gingival fibroblast well-being 171
A new D2 dopamine receptor agonist allosterically modulates A2A adenosine receptor signalling by interacting with the A2A/D2 receptor heteromer 170
Modulation of A2B adenosine receptor by 1-benzyl-3-ketoindole derivatives 169
Intracellular bioinorganic chemistry and cross talk among different - omics 159
Copper (II) ions modulate Angiogenin activity in human endothelial cells 156
Synthesis, chemical characterization, and biological evaluation of a novel auranofin derivative as an anticancer agent 153
An irreversible ligand of the 18 kDa Translocator Protein induces rapidly ΔΨm collapse and activates apoptosis in human glioblastoma multiforme cells. 153
Novel fluorescent triazinobenzimidazole derivatives as probes for labelling human A1 and A2B adenosine receptor subtypes 153
Cornus sanguinea Fruits: a Source of Antioxidant and Antisenescence Compounds Acting on Aged Human Dermal and Gingival Fibroblasts 153
Cytokine secretion responsiveness of lymphomonocytes following cortisol cell exposure: Sex differences 150
Potential biomarkers and novel pharmacological targets in protein aggregation-related neurodegenerative diseases 149
Novel positive allosteric modulators of A2B adenosine receptor acting as bone mineralisation promoters 145
Powerful twin carboxylic inhibitors for MMP homodimerization 142
Microglial pro-inflammatory and anti-inflammatory phenotypes are modulated by translocator protein activation 142
Copper binding to naturally occurring, lactam form of angiogenin differs from that to recombinant protein, affecting their activity 141
Human gingival mesenchymal stem cell trophism is modulated by inflammatory microenvironment: effects of ribes nigrum bud extract 141
The mesenchymal stem cell differentiation to osteoblasts is potentiate by the allosteric modulation of A2B adenosine receptors. 138
De novo neurosteroidogenesis in human microglia: Involvement of the 18 kda translocator protein 135
Multimaterial and multiscale scaffold for engineering enthesis organ 134
TUMOR NECROSIS FACTOR ALPHA TRIGGERS OSTEOGENESIS THROUGH THE INVOVLVEMENT OF Gs-COUPLED RECEPTOR SIGNALS 134
Compounds with a benzo [a]carbazole structure for use in the prevention and/or treatment of infectious diseases 133
ROLE OF ADENOSINE RECEPTORS IN SURVIVAL AND DIFFERENTIATION OF GLIOBLASTOMA STEM CELLS 132
Allosterism vs. Orthosterism: Recent Findings and Future Perspectives on A2B AR Physio-Pathological Implications 132
Allosteric Modulators of Adenosine Receptors 130
Allosteric modulation of A2B adenosine receptors potentiate the effects of orthosteric receptor agonists to promote mesenchymal stem cell differentiation to osteoblasts. 130
Refinement of the Mitochondrial Translocator Protein Pharmacophore/Receptor Model via Structure-activity Relationships of Novel N,N-Dialkylindolylglyoxylamides 128
Advances in microglia cellular models: Focus on extracellular vesicle production 126
The ionophoric activity of a pro-apoptotic vegf165 fragment on huvec cells 125
null 122
High adenosine extracellular levels induce glioblastoma aggressive traits modulating the mesenchymal stromal cell secretome 122
Human Microglia Extracellular Vesicles Derived from Different Microglia Cell Lines: Similarities and Differences 121
null 120
Allosteric modulation of A2B adenosine receptors favours mesenchymal stem cell differentiation to osteoblasts. 119
Glioblastoma multiforme: induction of mitochondria-mediated apoptotic pathway by simultaneous pharmacological activation of TSPO (18KDa) and p53. 117
Human oligodendrocyte-like cell differentiation is promoted by TSPO-mediated endogenous steroidogenesis 116
Refinement of the Mitochondrial Translocator Protein Pharmacophore/Receptor Model via Structure-activity Relationships of Novel N,N-Dialkylindolylglyoxylamides 116
Brain ageing and neurodegenerative disease: The role of cellular waste management 116
Interaction of the irreversible ligand IRDE-MPIGA with TSPO (18 KDa): new insight on TSPO role in tumor cells. 115
Agonist-induced desensitization of GPR17 in oligodendrocyte precursor cells:a role in the maturation to myelinating cells 115
GFP Farnesylation as a Suitable Strategy for Selectively Tagging Exosomes 114
Dual MET and SMO Negative Modulators Overcome Resistance to EGFR Inhibitors in Human Nonsmall Cell Lung Cancer 113
Intermittent hypoxia treatments cause cellular priming in human microglia 112
New insights on the human bone-marrow and gingival mesenchymal stem cell responses to senescence induction 109
18 kDa TSPO targeting drives polarized human microglia towards a protective and restorative neurosteroidome profile 108
N,N-dialkyl-5-isothiocyanato-2-phenylindol-3-ylglyoxylamide: an irreversible ligand to study the translocator protein 103
Ruthenium(II) 1,4,7-trithiacyclononane complexes of curcumin and bisdemethoxycurcumin: Synthesis, characterization, and biological activity 101
Synthetic agents for protein dimerization, a bridge between chemistry and biology for protein characterization and potential drug development. 99
Identification of a Novel p53 Modulator Endowed with Antitumoural and Antibacterial Activity through a Scaffold Repurposing Approach 98
Extracellular adenosine oppositely regulates the purinome machinery in glioblastoma and mesenchymal stem cells 96
New Pyrazolo[1',5':1,6]pyrimido[4,5-d]pyridazin-4(3H)-ones Fluoroderivatives as Human A1 Adenosine Receptor Ligands. 96
Regulation of the P2Y-like receptor by agonist-induced desensitization in transfected 1321N1 cells. 96
Angiogenin-mimetic peptide functionalised gold nanoparticles for cancer therapy applications 95
Microglia extracellular vesicles: Focus on molecular composition and biological function 95
Oxaliplatin(IV) Prodrugs Functionalized with Gemcitabine and Capecitabine Induce Blockage of Colorectal Cancer Cell Growth - An Investigation of the Activation Mechanism and Their Nanoformulation 94
COMPOUNDS WITH A BENZO[A]CARBAZOLE STRUCTURE AND USE THEREOF 94
Blood oxygenation state in COVID-19 patients: Unexplored role of 2,3-bisphosphoglycerate 92
From conventional therapy to novel nano-based approaches. A focus on prostate cancer 92
INTERMITTENT HYPOXIA PROMOTES CELLULAR PRIMING AND EXAGGERATED INFLAMMATORY RESPONSE OF HUMAN MICROGLIA IN VITRO 91
Interaction of graphene and WS2 with neutrophils and mesenchymal stem cells: implications for peripheral nerve regeneration 88
null 85
Inhibition of metalloproteases with dimeric ligands – A Crystallographic study 84
4-amino-6-alkyloxy-2-alkylthiopyrimidine derivatives as novel non-nucleoside agonists for the adenosine A1 receptor 78
Editorial: Molecular Insights Into Ligand-Receptor Interactions on the Cell Surface 74
Dimolybdenum (II,II) paddlewheel complexes bearing non-steroidal anti-inflammatory drug ligands: Insights into the chemico-physical profile and first biological assessment 74
N,N-dialkyl-5-isothiocyanato-2-phenylindol-3-ylglyoxylamide: an irreversible ligand to study the translocator protein 71
Editorial: Physical Activity: Epigenetic and Metabolic Regulation of Brain Aging 71
null 71
Pulmonary fibrosis from molecular mechanisms to therapeutic interventions: lessons from post-COVID-19 patients 69
Totale 14.602
Categoria #
all - tutte 40.364
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 40.364


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021694 0 0 0 0 0 52 39 90 204 139 44 126
2021/2022997 33 63 26 51 152 156 56 56 44 40 40 280
2022/20231.518 175 184 118 142 158 188 23 118 279 12 86 35
2023/20241.192 89 91 162 73 159 193 77 32 25 42 99 150
2024/20253.437 27 121 52 242 333 361 266 133 382 394 351 775
2025/20262.754 261 527 621 489 540 316 0 0 0 0 0 0
Totale 15.074