GIACOMELLI, CHIARA
 Distribuzione geografica
Continente #
NA - Nord America 4.587
EU - Europa 3.147
AS - Asia 871
AF - Africa 138
OC - Oceania 23
SA - Sud America 9
Continente sconosciuto - Info sul continente non disponibili 2
Totale 8.777
Nazione #
US - Stati Uniti d'America 4.409
IT - Italia 1.729
CN - Cina 380
SE - Svezia 378
DE - Germania 277
SG - Singapore 232
BG - Bulgaria 192
CA - Canada 174
AT - Austria 119
FR - Francia 104
VN - Vietnam 99
GB - Regno Unito 91
UA - Ucraina 57
SN - Senegal 51
FI - Finlandia 50
RU - Federazione Russa 46
NG - Nigeria 45
HK - Hong Kong 36
IN - India 34
CI - Costa d'Avorio 33
TR - Turchia 29
AU - Australia 22
BE - Belgio 21
KR - Corea 17
NL - Olanda 16
PL - Polonia 16
PK - Pakistan 12
CH - Svizzera 10
JP - Giappone 10
ES - Italia 9
CZ - Repubblica Ceca 7
ID - Indonesia 7
IR - Iran 7
EG - Egitto 4
GR - Grecia 4
RO - Romania 4
RS - Serbia 4
BR - Brasile 3
HR - Croazia 3
MA - Marocco 3
PT - Portogallo 3
SK - Slovacchia (Repubblica Slovacca) 3
TW - Taiwan 3
A1 - Anonimo 2
CL - Cile 2
CO - Colombia 2
IL - Israele 2
MX - Messico 2
BJ - Benin 1
EC - Ecuador 1
EE - Estonia 1
GE - Georgia 1
IE - Irlanda 1
JM - Giamaica 1
LK - Sri Lanka 1
LT - Lituania 1
NZ - Nuova Zelanda 1
PA - Panama 1
PE - Perù 1
PH - Filippine 1
SI - Slovenia 1
ZA - Sudafrica 1
Totale 8.777
Città #
Serra 741
Woodbridge 545
Ann Arbor 497
Fairfield 466
Houston 364
Chandler 351
Ashburn 282
Seattle 194
Sofia 192
Beijing 166
Wilmington 160
Ottawa 158
Milan 146
New York 144
Cambridge 142
Boardman 132
Princeton 111
Vienna 109
Singapore 83
Pisa 74
Lawrence 73
Medford 71
Des Moines 62
Dakar 51
Nanjing 49
Lagos 45
Rho 44
Florence 43
Bremen 42
Dong Ket 41
Frankfurt am Main 40
Lucca 39
Livorno 36
Abidjan 33
Dearborn 33
Alessandria 32
Hong Kong 32
Los Angeles 32
Redwood City 29
Boulder 28
Guangzhou 28
London 28
Kent 21
Ogden 21
Brussels 20
Chicago 20
Nanchang 17
Jacksonville 16
Kunming 15
Pistoia 15
Rome 15
Hefei 14
San Diego 13
Sydney 13
Washington 13
Marseille 12
Dallas 11
Phoenix 11
Falls Church 10
Izmir 10
Nürnberg 10
Pessac 10
Cascina 9
Konya 9
Shenyang 9
Warsaw 9
Changsha 8
Jiaxing 8
San Giuliano Terme 8
Toronto 8
Auburn Hills 7
Hebei 7
Lancaster 7
Massa 7
Naples 7
Paris 7
Pune 7
Tianjin 6
Catania 5
Garbagnate Milanese 5
Helsinki 5
Jinan 5
Norwalk 5
Padova 5
Santa Margherita Ligure 5
Bern 4
Bologna 4
Capannori 4
Caserta 4
Dortmund 4
Genova 4
Guwahati 4
Hangzhou 4
Leawood 4
Maidstone 4
Pian Camuno 4
Tangerang 4
Altopascio 3
Amantea 3
Bonn 3
Totale 6.470
Nome #
TSPO ligand residence time influences human glioblastoma multiforme cell death/life balance 252
Apoptosis Therapy in Cancer: The First Single-molecule Co-activating p53 and the Translocator Protein in Glioblastoma 216
Bax Activation Blocks Self-Renewal and Induces Apoptosis of Human Glioblastoma Stem Cells 185
Osteogenesis Is Improved by Low Tumor Necrosis Factor Alpha Concentration through the Modulation of Gs-Coupled Receptor Signals 181
Allosteric modulators of human A2B adenosine receptor. 180
New insights into the anticancer activity of carnosol: P53 reactivation in the U87MG human glioblastoma cell line 170
Deepening the Topology of the Translocator Protein Binding Site by Novel N,N-Dialkyl-2-arylindol-3-ylglyoxylamides 166
Bifunctional Inhibitors as a New Tool To Reduce Cancer Cell Invasion by Impairing MMP-9 Homodimerization 165
Dual inhibition of PDK1 and Aurora Kinase A: an effective strategy to induce differentiation and apoptosis of human glioblastoma multiforme stem cells 165
Phytochemical analysis and antisenescence activity of Sorbus torminalis (L.) Crantz and Elaeagnus umbellata Thunb fruits 165
TSPO ligand residence time: a new parameter to predict compound neurosteroidogenic efficacy 163
TSPO PIGA ligands promote neurosteroidogenesis and human astrocyte well-being 162
G PROTEIN-COUPLED RECEPTOR DESENSITISATION REGULATES STEM CELL DIFFERENTIATION 153
Drug-target Residence Time: a key parameter in glial responses to TSPO ligands 149
α-Synuclein Heterocomplexes with β-Amyloid Are Increased in Red Blood Cells of Parkinson's Disease Patients and Correlate with Disease Severity 146
α-Synuclein Aggregated with Tau and β-Amyloid in Human Platelets from Healthy Subjects: Correlation with Physical Exercise 144
Further studies on pyrazolo[1',5':1,6]pyrimido[4,5-d]pyridazin-4(3H)-ones as potent and selective human A1 adenosine receptor antagonists. 142
A new D2 dopamine receptor agonist allosterically modulates A2A adenosine receptor signalling by interacting with the A2A/D2 receptor heteromer 140
Lactate dehydrogenase-A inhibition induces human glioblastoma multiforme stem cell differentiation and death 139
Discovery of N-Hydroxyindole-Based Inhibitors of Human Lactate Dehydrogenase Isoform a (LDH-A) as Starvation Agents against Cancer Cells 138
Epigenetic Modifications of the α-Synuclein Gene and Relative Protein Content Are Affected by Ageing and Physical Exercise in Blood from Healthy Subjects 138
Carnosol controls the human glioblastoma stemness features through the epithelial-mesenchymal transition modulation and the induction of cancer stem cell apoptosis 137
Modulation of A2B Adenosine Receptor by 1-Benzyl-3-ketoindole Derivatives 136
Targeting the 18-kDa translocator protein: Recent perspectives for neuroprotection 134
Osteoblast differentiation and survival: A role for A2B adenosine receptor allosteric modulators. 132
Effect of Ribes nigrum bud extract on human gingival mesenchymal stem cell cytokine release: a role on regenerative processes 130
Long lasting inhibition of Mdm2-p53 interaction potentiates mesenchymal stem cell differentiation into osteoblasts 130
Modulation of A2B adenosine receptor by 1-benzyl-3-ketoindole derivatives 129
p53 Functional Inhibitors Behaving Like Pifithrin-β Counteract the Alzheimer Peptide Non-β-amyloid Component Effects in Human SH-SY5Y Cells. 128
Negative effects of a high tumour necrosis factor-α concentration on human gingival mesenchymal stem cell trophism: The use of natural compounds as modulatory agents 128
Intracellular bioinorganic chemistry and cross talk among different - omics 126
The A2B adenosine receptor modulates the epithelial- mesenchymal transition through the balance of cAMP/PKA and MAPK/ERK pathway activation in human epithelial lung cells 124
null 122
Potential biomarkers and novel pharmacological targets in protein aggregation-related neurodegenerative diseases 120
Antioxidant activity of compounds isolated from Elaeagnus umbellata promotes human gingival fibroblast well-being 120
Molecular insight on the altered membrane trafficking of TrkA kinase dead mutants 114
An irreversible ligand of the 18 kDa Translocator Protein induces rapidly ΔΨm collapse and activates apoptosis in human glioblastoma multiforme cells. 111
Novel fluorescent triazinobenzimidazole derivatives as probes for labelling human A1 and A2B adenosine receptor subtypes 111
Powerful twin carboxylic inhibitors for MMP homodimerization 106
Copper (II) ions modulate Angiogenin activity in human endothelial cells 106
Copper binding to naturally occurring, lactam form of angiogenin differs from that to recombinant protein, affecting their activity 106
Novel positive allosteric modulators of A2B adenosine receptor acting as bone mineralisation promoters 101
Cornus sanguinea Fruits: a Source of Antioxidant and Antisenescence Compounds Acting on Aged Human Dermal and Gingival Fibroblasts 101
Allosteric modulation of A2B adenosine receptors potentiate the effects of orthosteric receptor agonists to promote mesenchymal stem cell differentiation to osteoblasts. 100
Human gingival mesenchymal stem cell trophism is modulated by inflammatory microenvironment: effects of ribes nigrum bud extract 99
Cytokine secretion responsiveness of lymphomonocytes following cortisol cell exposure: Sex differences 97
The mesenchymal stem cell differentiation to osteoblasts is potentiate by the allosteric modulation of A2B adenosine receptors. 95
Microglial pro-inflammatory and anti-inflammatory phenotypes are modulated by translocator protein activation 92
The ionophoric activity of a pro-apoptotic vegf165 fragment on huvec cells 92
De novo neurosteroidogenesis in human microglia: Involvement of the 18 kda translocator protein 91
Brain ageing and neurodegenerative disease: The role of cellular waste management 88
Agonist-induced desensitization of GPR17 in oligodendrocyte precursor cells:a role in the maturation to myelinating cells 87
null 85
Glioblastoma multiforme: induction of mitochondria-mediated apoptotic pathway by simultaneous pharmacological activation of TSPO (18KDa) and p53. 84
Dual MET and SMO Negative Modulators Overcome Resistance to EGFR Inhibitors in Human Nonsmall Cell Lung Cancer 84
ROLE OF ADENOSINE RECEPTORS IN SURVIVAL AND DIFFERENTIATION OF GLIOBLASTOMA STEM CELLS 81
TUMOR NECROSIS FACTOR ALPHA TRIGGERS OSTEOGENESIS THROUGH THE INVOVLVEMENT OF Gs-COUPLED RECEPTOR SIGNALS 79
Refinement of the Mitochondrial Translocator Protein Pharmacophore/Receptor Model via Structure-activity Relationships of Novel N,N-Dialkylindolylglyoxylamides 77
Allosterism vs. Orthosterism: Recent Findings and Future Perspectives on A2B AR Physio-Pathological Implications 73
null 71
Interaction of the irreversible ligand IRDE-MPIGA with TSPO (18 KDa): new insight on TSPO role in tumor cells. 70
Allosteric modulation of A2B adenosine receptors favours mesenchymal stem cell differentiation to osteoblasts. 69
Neurotrophic Activity and Its Modulation by Zinc Ion of a Dimeric Peptide Mimicking the Brain-Derived Neurotrophic Factor N-Terminal Region 68
Regulation of the P2Y-like receptor by agonist-induced desensitization in transfected 1321N1 cells. 68
New insights on the human bone-marrow and gingival mesenchymal stem cell responses to senescence induction 66
Synthetic agents for protein dimerization, a bridge between chemistry and biology for protein characterization and potential drug development. 64
New Pyrazolo[1',5':1,6]pyrimido[4,5-d]pyridazin-4(3H)-ones Fluoroderivatives as Human A1 Adenosine Receptor Ligands. 63
null 63
N,N-dialkyl-5-isothiocyanato-2-phenylindol-3-ylglyoxylamide: an irreversible ligand to study the translocator protein 57
Synthesis, chemical characterization, and biological evaluation of a novel auranofin derivative as an anticancer agent 56
Refinement of the Mitochondrial Translocator Protein Pharmacophore/Receptor Model via Structure-activity Relationships of Novel N,N-Dialkylindolylglyoxylamides 52
High adenosine extracellular levels induce glioblastoma aggressive traits modulating the mesenchymal stromal cell secretome 52
Advances in microglia cellular models: Focus on extracellular vesicle production 46
Editorial: Physical Activity: Epigenetic and Metabolic Regulation of Brain Aging 44
Intermittent hypoxia treatments cause cellular priming in human microglia 44
Apolipoprotein E ε4 triggers neurotoxicity via cholesterol accumulation, acetylcholine dyshomeostasis, and PKCε mislocalization in cholinergic neuronal cells 43
Inhibition of metalloproteases with dimeric ligands – A Crystallographic study 43
COMPOUNDS WITH A BENZO[A]CARBAZOLE STRUCTURE AND USE THEREOF 43
Ruthenium(II) 1,4,7-trithiacyclononane complexes of curcumin and bisdemethoxycurcumin: Synthesis, characterization, and biological activity 43
N,N-dialkyl-5-isothiocyanato-2-phenylindol-3-ylglyoxylamide: an irreversible ligand to study the translocator protein 40
Regulation Of The P2Y-Like Receptor GPR17 By Agonist-Induced Desensitization 37
4-amino-6-alkyloxy-2-alkylthiopyrimidine derivatives as novel non-nucleoside agonists for the adenosine A1 receptor 36
Microglia extracellular vesicles: Focus on molecular composition and biological function 35
Compounds with a benzo [a]carbazole structure for use in the prevention and/or treatment of infectious diseases 33
Angiogenin-mimetic peptide functionalised gold nanoparticles for cancer therapy applications 33
Pulmonary fibrosis from molecular mechanisms to therapeutic interventions: lessons from post-COVID-19 patients 31
Multimaterial and multiscale scaffold for engineering enthesis organ 26
Identification of a Novel p53 Modulator Endowed with Antitumoural and Antibacterial Activity through a Scaffold Repurposing Approach 25
INTERMITTENT HYPOXIA PROMOTES CELLULAR PRIMING AND EXAGGERATED INFLAMMATORY RESPONSE OF HUMAN MICROGLIA IN VITRO 25
Human Microglia Extracellular Vesicles Derived from Different Microglia Cell Lines: Similarities and Differences 24
Allosteric Modulators of Adenosine Receptors 23
Toward PET imaging of A2B adenosine receptors: A carbon-11 labeled triazinobenzimidazole tracer. Synthesis and imaging of a new A2B PET tracer 22
Interaction of graphene and WS2 with neutrophils and mesenchymal stem cells: implications for peripheral nerve regeneration 19
Editorial: Molecular Insights Into Ligand-Receptor Interactions on the Cell Surface 17
Human oligodendrocyte-like cell differentiation is promoted by TSPO-mediated endogenous steroidogenesis 13
Oxaliplatin(IV) Prodrugs Functionalized with Gemcitabine and Capecitabine Induce Blockage of Colorectal Cancer Cell Growth - An Investigation of the Activation Mechanism and Their Nanoformulation 12
Dimolybdenum (II,II) paddlewheel complexes bearing non-steroidal anti-inflammatory drug ligands: Insights into the chemico-physical profile and first biological assessment 8
Graphene-based nanomaterials for peripheral nerve regeneration 4
Totale 9.103
Categoria #
all - tutte 24.501
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 24.501


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20201.045 0 0 0 75 107 143 158 121 169 114 117 41
2020/20211.005 121 63 50 25 52 52 39 90 204 139 44 126
2021/2022997 33 63 26 51 152 156 56 56 44 40 40 280
2022/20231.518 175 184 118 142 158 188 23 118 279 12 86 35
2023/20241.192 89 91 162 73 159 193 77 32 25 42 99 150
2024/2025220 27 121 52 20 0 0 0 0 0 0 0 0
Totale 9.103