GIACOMELLI, CHIARA
 Distribuzione geografica
Continente #
NA - Nord America 7.724
AS - Asia 4.364
EU - Europa 4.248
SA - Sud America 556
AF - Africa 233
OC - Oceania 27
Continente sconosciuto - Info sul continente non disponibili 3
Totale 17.155
Nazione #
US - Stati Uniti d'America 7.422
IT - Italia 2.102
SG - Singapore 1.287
CN - Cina 1.178
VN - Vietnam 690
HK - Hong Kong 536
BR - Brasile 475
DE - Germania 397
SE - Svezia 386
CA - Canada 230
FR - Francia 226
BG - Bulgaria 192
GB - Regno Unito 181
FI - Finlandia 149
AT - Austria 136
RU - Federazione Russa 126
TR - Turchia 110
IN - India 107
JP - Giappone 105
KR - Corea 68
UA - Ucraina 62
NL - Olanda 55
SN - Senegal 52
NG - Nigeria 50
PL - Polonia 45
IQ - Iraq 42
EE - Estonia 38
BD - Bangladesh 37
PK - Pakistan 37
MX - Messico 36
CI - Costa d'Avorio 35
CH - Svizzera 32
ID - Indonesia 29
ZA - Sudafrica 28
AU - Australia 26
ES - Italia 26
BE - Belgio 24
AR - Argentina 21
EG - Egitto 20
UZ - Uzbekistan 16
EC - Ecuador 15
MA - Marocco 15
SA - Arabia Saudita 14
MY - Malesia 12
KE - Kenya 11
LT - Lituania 11
CO - Colombia 10
IR - Iran 10
JO - Giordania 10
PH - Filippine 10
VE - Venezuela 10
AZ - Azerbaigian 9
CZ - Repubblica Ceca 9
JM - Giamaica 9
IE - Irlanda 8
AE - Emirati Arabi Uniti 7
IL - Israele 7
PT - Portogallo 7
TW - Taiwan 7
CL - Cile 6
GR - Grecia 6
RO - Romania 6
RS - Serbia 6
TN - Tunisia 6
UY - Uruguay 6
KG - Kirghizistan 5
NP - Nepal 5
PA - Panama 5
BH - Bahrain 4
BO - Bolivia 4
CR - Costa Rica 4
ET - Etiopia 4
GT - Guatemala 4
PE - Perù 4
TT - Trinidad e Tobago 4
AL - Albania 3
HR - Croazia 3
LB - Libano 3
QA - Qatar 3
SK - Slovacchia (Repubblica Slovacca) 3
TH - Thailandia 3
A1 - Anonimo 2
BA - Bosnia-Erzegovina 2
DO - Repubblica Dominicana 2
DZ - Algeria 2
GE - Georgia 2
GY - Guiana 2
HN - Honduras 2
HU - Ungheria 2
KW - Kuwait 2
KZ - Kazakistan 2
NI - Nicaragua 2
OM - Oman 2
PR - Porto Rico 2
PS - Palestinian Territory 2
PY - Paraguay 2
SI - Slovenia 2
AM - Armenia 1
AO - Angola 1
BB - Barbados 1
Totale 17.137
Città #
Ashburn 742
Serra 742
Singapore 648
Dallas 625
Woodbridge 546
Hong Kong 518
Ann Arbor 497
Fairfield 467
San Jose 434
Santa Clara 405
Houston 372
Chandler 351
Beijing 250
Shanghai 227
Ho Chi Minh City 201
Seattle 197
Sofia 192
Los Angeles 177
New York 177
Milan 171
Wilmington 161
Ottawa 159
Hanoi 155
Boardman 145
Cambridge 142
Pisa 140
Vienna 119
Council Bluffs 114
Princeton 111
Tokyo 90
Hefei 85
Florence 80
Lauterbourg 74
Frankfurt am Main 73
Lawrence 73
Medford 72
Helsinki 71
Des Moines 62
London 57
Lucca 54
Dakar 52
Munich 52
Nanjing 49
Seoul 49
Livorno 47
Lagos 45
Rho 44
Bremen 42
Dong Ket 41
São Paulo 41
Redondo Beach 40
Buffalo 39
Chicago 38
Istanbul 38
Tallinn 38
Abidjan 35
Dearborn 34
Guangzhou 34
Rome 34
Alessandria 32
Warsaw 32
Da Nang 29
Orem 29
Redwood City 29
Boulder 28
Columbus 28
Haiphong 27
Turku 26
Brussels 23
Kent 22
Ogden 21
Pistoia 21
Jacksonville 20
Nuremberg 20
Phoenix 19
San Giuliano Terme 19
The Dalles 19
Toronto 19
Zurich 19
Montreal 18
Nanchang 18
Amsterdam 16
Chennai 16
Denver 16
Johannesburg 16
Kunming 16
Rio de Janeiro 16
Washington 16
Baltimore 15
Paris 15
Atlanta 14
Baghdad 14
Naples 14
San Diego 14
Tashkent 14
Fuzhou 13
Manchester 13
Pune 13
Sydney 13
Düsseldorf 12
Totale 11.562
Nome #
TSPO ligand residence time influences human glioblastoma multiforme cell death/life balance 333
G PROTEIN-COUPLED RECEPTOR DESENSITISATION REGULATES STEM CELL DIFFERENTIATION 333
Apoptosis Therapy in Cancer: The First Single-molecule Co-activating p53 and the Translocator Protein in Glioblastoma 275
α-Synuclein Aggregated with Tau and β-Amyloid in Human Platelets from Healthy Subjects: Correlation with Physical Exercise 273
Force induces axon growth in inhibitory conditions 265
TSPO PIGA ligands promote neurosteroidogenesis and human astrocyte well-being 263
New insights into the anticancer activity of carnosol: P53 reactivation in the U87MG human glioblastoma cell line 263
Phytochemical analysis and antisenescence activity of Sorbus torminalis (L.) Crantz and Elaeagnus umbellata Thunb fruits 262
Bax Activation Blocks Self-Renewal and Induces Apoptosis of Human Glioblastoma Stem Cells 253
Deepening the Topology of the Translocator Protein Binding Site by Novel N,N-Dialkyl-2-arylindol-3-ylglyoxylamides 243
Osteogenesis Is Improved by Low Tumor Necrosis Factor Alpha Concentration through the Modulation of Gs-Coupled Receptor Signals 235
Apolipoprotein E ε4 triggers neurotoxicity via cholesterol accumulation, acetylcholine dyshomeostasis, and PKCε mislocalization in cholinergic neuronal cells 234
α-Synuclein Heterocomplexes with β-Amyloid Are Increased in Red Blood Cells of Parkinson's Disease Patients and Correlate with Disease Severity 232
Allosteric modulators of human A2B adenosine receptor. 231
Dual inhibition of PDK1 and Aurora Kinase A: an effective strategy to induce differentiation and apoptosis of human glioblastoma multiforme stem cells 231
Effect of Ribes nigrum bud extract on human gingival mesenchymal stem cell cytokine release: a role on regenerative processes 231
TSPO ligand residence time: a new parameter to predict compound neurosteroidogenic efficacy 231
Carnosol controls the human glioblastoma stemness features through the epithelial-mesenchymal transition modulation and the induction of cancer stem cell apoptosis 217
p53 Functional Inhibitors Behaving Like Pifithrin-β Counteract the Alzheimer Peptide Non-β-amyloid Component Effects in Human SH-SY5Y Cells. 216
Bifunctional Inhibitors as a New Tool To Reduce Cancer Cell Invasion by Impairing MMP-9 Homodimerization 214
Long lasting inhibition of Mdm2-p53 interaction potentiates mesenchymal stem cell differentiation into osteoblasts 213
Synthesis, chemical characterization, and biological evaluation of a novel auranofin derivative as an anticancer agent 208
Lactate dehydrogenase-A inhibition induces human glioblastoma multiforme stem cell differentiation and death 207
Neurotrophic Activity and Its Modulation by Zinc Ion of a Dimeric Peptide Mimicking the Brain-Derived Neurotrophic Factor N-Terminal Region 204
Epigenetic Modifications of the α-Synuclein Gene and Relative Protein Content Are Affected by Ageing and Physical Exercise in Blood from Healthy Subjects 202
Discovery of N-Hydroxyindole-Based Inhibitors of Human Lactate Dehydrogenase Isoform a (LDH-A) as Starvation Agents against Cancer Cells 199
Drug-target Residence Time: a key parameter in glial responses to TSPO ligands 196
Negative effects of a high tumour necrosis factor-α concentration on human gingival mesenchymal stem cell trophism: The use of natural compounds as modulatory agents 194
Antioxidant activity of compounds isolated from Elaeagnus umbellata promotes human gingival fibroblast well-being 194
Osteoblast differentiation and survival: A role for A2B adenosine receptor allosteric modulators. 190
Novel positive allosteric modulators of A2B adenosine receptor acting as bone mineralisation promoters 189
Novel fluorescent triazinobenzimidazole derivatives as probes for labelling human A1 and A2B adenosine receptor subtypes 188
The A2B adenosine receptor modulates the epithelial- mesenchymal transition through the balance of cAMP/PKA and MAPK/ERK pathway activation in human epithelial lung cells 187
A new D2 dopamine receptor agonist allosterically modulates A2A adenosine receptor signalling by interacting with the A2A/D2 receptor heteromer 187
An irreversible ligand of the 18 kDa Translocator Protein induces rapidly ΔΨm collapse and activates apoptosis in human glioblastoma multiforme cells. 186
Further studies on pyrazolo[1',5':1,6]pyrimido[4,5-d]pyridazin-4(3H)-ones as potent and selective human A1 adenosine receptor antagonists. 185
Modulation of A2B adenosine receptor by 1-benzyl-3-ketoindole derivatives 183
Targeting the 18-kDa translocator protein: Recent perspectives for neuroprotection 180
Modulation of A2B Adenosine Receptor by 1-Benzyl-3-ketoindole Derivatives 179
Multimaterial and multiscale scaffold for engineering enthesis organ 178
De novo neurosteroidogenesis in human microglia: Involvement of the 18 kda translocator protein 174
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Cornus sanguinea Fruits: a Source of Antioxidant and Antisenescence Compounds Acting on Aged Human Dermal and Gingival Fibroblasts 172
Copper (II) ions modulate Angiogenin activity in human endothelial cells 168
Allosteric modulation of A2B adenosine receptors potentiate the effects of orthosteric receptor agonists to promote mesenchymal stem cell differentiation to osteoblasts. 167
Cytokine secretion responsiveness of lymphomonocytes following cortisol cell exposure: Sex differences 167
Intracellular bioinorganic chemistry and cross talk among different - omics 167
Compounds with a benzo [a]carbazole structure for use in the prevention and/or treatment of infectious diseases 164
Microglial pro-inflammatory and anti-inflammatory phenotypes are modulated by translocator protein activation 164
TUMOR NECROSIS FACTOR ALPHA TRIGGERS OSTEOGENESIS THROUGH THE INVOVLVEMENT OF Gs-COUPLED RECEPTOR SIGNALS 163
Potential biomarkers and novel pharmacological targets in protein aggregation-related neurodegenerative diseases 158
Human gingival mesenchymal stem cell trophism is modulated by inflammatory microenvironment: effects of ribes nigrum bud extract 158
Copper binding to naturally occurring, lactam form of angiogenin differs from that to recombinant protein, affecting their activity 157
Powerful twin carboxylic inhibitors for MMP homodimerization 155
Intermittent hypoxia treatments cause cellular priming in human microglia 155
Extracellular adenosine oppositely regulates the purinome machinery in glioblastoma and mesenchymal stem cells 153
Allosteric Modulators of Adenosine Receptors 152
The mesenchymal stem cell differentiation to osteoblasts is potentiate by the allosteric modulation of A2B adenosine receptors. 152
GFP Farnesylation as a Suitable Strategy for Selectively Tagging Exosomes 151
ROLE OF ADENOSINE RECEPTORS IN SURVIVAL AND DIFFERENTIATION OF GLIOBLASTOMA STEM CELLS 151
Advances in microglia cellular models: Focus on extracellular vesicle production 148
Interaction of the irreversible ligand IRDE-MPIGA with TSPO (18 KDa): new insight on TSPO role in tumor cells. 147
Allosterism vs. Orthosterism: Recent Findings and Future Perspectives on A2B AR Physio-Pathological Implications 146
18 kDa TSPO targeting drives polarized human microglia towards a protective and restorative neurosteroidome profile 142
Human Microglia Extracellular Vesicles Derived from Different Microglia Cell Lines: Similarities and Differences 141
Refinement of the Mitochondrial Translocator Protein Pharmacophore/Receptor Model via Structure-activity Relationships of Novel N,N-Dialkylindolylglyoxylamides 140
N,N-dialkyl-5-isothiocyanato-2-phenylindol-3-ylglyoxylamide: an irreversible ligand to study the translocator protein 134
High adenosine extracellular levels induce glioblastoma aggressive traits modulating the mesenchymal stromal cell secretome 133
Brain ageing and neurodegenerative disease: The role of cellular waste management 131
Glioblastoma multiforme: induction of mitochondria-mediated apoptotic pathway by simultaneous pharmacological activation of TSPO (18KDa) and p53. 130
Dual MET and SMO Negative Modulators Overcome Resistance to EGFR Inhibitors in Human Nonsmall Cell Lung Cancer 130
New insights on the human bone-marrow and gingival mesenchymal stem cell responses to senescence induction 129
The ionophoric activity of a pro-apoptotic vegf165 fragment on huvec cells 128
Blood oxygenation state in COVID-19 patients: Unexplored role of 2,3-bisphosphoglycerate 127
Oxaliplatin(IV) Prodrugs Functionalized with Gemcitabine and Capecitabine Induce Blockage of Colorectal Cancer Cell Growth - An Investigation of the Activation Mechanism and Their Nanoformulation 126
Allosteric modulation of A2B adenosine receptors favours mesenchymal stem cell differentiation to osteoblasts. 125
Refinement of the Mitochondrial Translocator Protein Pharmacophore/Receptor Model via Structure-activity Relationships of Novel N,N-Dialkylindolylglyoxylamides 125
Agonist-induced desensitization of GPR17 in oligodendrocyte precursor cells:a role in the maturation to myelinating cells 123
Ruthenium(II) 1,4,7-trithiacyclononane complexes of curcumin and bisdemethoxycurcumin: Synthesis, characterization, and biological activity 123
Identification of a Novel p53 Modulator Endowed with Antitumoural and Antibacterial Activity through a Scaffold Repurposing Approach 122
From conventional therapy to novel nano-based approaches. A focus on prostate cancer 122
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Microglia extracellular vesicles: Focus on molecular composition and biological function 112
Regulation of the P2Y-like receptor by agonist-induced desensitization in transfected 1321N1 cells. 108
Synthetic agents for protein dimerization, a bridge between chemistry and biology for protein characterization and potential drug development. 107
Interaction of graphene and WS2 with neutrophils and mesenchymal stem cells: implications for peripheral nerve regeneration 105
INTERMITTENT HYPOXIA PROMOTES CELLULAR PRIMING AND EXAGGERATED INFLAMMATORY RESPONSE OF HUMAN MICROGLIA IN VITRO 105
Angiogenin-mimetic peptide functionalised gold nanoparticles for cancer therapy applications 101
COMPOUNDS WITH A BENZO[A]CARBAZOLE STRUCTURE AND USE THEREOF 101
New Pyrazolo[1',5':1,6]pyrimido[4,5-d]pyridazin-4(3H)-ones Fluoroderivatives as Human A1 Adenosine Receptor Ligands. 100
Pulmonary fibrosis from molecular mechanisms to therapeutic interventions: lessons from post-COVID-19 patients 96
Inhibition of metalloproteases with dimeric ligands – A Crystallographic study 95
Editorial: Molecular Insights Into Ligand-Receptor Interactions on the Cell Surface 90
4-amino-6-alkyloxy-2-alkylthiopyrimidine derivatives as novel non-nucleoside agonists for the adenosine A1 receptor 89
Dimolybdenum (II,II) paddlewheel complexes bearing non-steroidal anti-inflammatory drug ligands: Insights into the chemico-physical profile and first biological assessment 89
Extracellular vesicles as vehicles for small non-coding RNA therapeutics: standardization challenges for clinical translation 85
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Graphene-based nanomaterials for peripheral nerve regeneration 82
Serum Lactate Dehydrogenase Levels Reflect the Lung Injury Extension in COVID-19 Patients at Hospital Admission 82
Totale 16.751
Categoria #
all - tutte 45.440
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 45.440


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021126 0 0 0 0 0 0 0 0 0 0 0 126
2021/2022997 33 63 26 51 152 156 56 56 44 40 40 280
2022/20231.518 175 184 118 142 158 188 23 118 279 12 86 35
2023/20241.192 89 91 162 73 159 193 77 32 25 42 99 150
2024/20253.437 27 121 52 242 333 361 266 133 382 394 351 775
2025/20265.221 261 527 621 489 540 359 1.052 250 329 457 319 17
Totale 17.541